Další formáty:
BibTeX
LaTeX
RIS
@proceedings{1483942,
author = {Lízal, Tomáš and Šindelář, Vladimír},
booktitle = {53rd Advances in Organic, Bioorganic and Pharmaceutical Chemistry "Liblice 2018" 2-4 November 2018, Lázně Bělohrad, Czech Republic},
title = {Xylylene-Glycoluril Macrocycles},
year = {2018}
}
TY - CONF
ID - 1483942
AU - Lízal, Tomáš - Šindelář, Vladimír
PY - 2018
TI - Xylylene-Glycoluril Macrocycles
N2 - Bambusurils1 are potent anion receptors that are synthetized by acidic condensation of 2,4-disubstituted glycolurils and formaldehyde. They were used to detect and quantify anions in a complex mixture by NMR2. In order to allow anion sensing by UV-VIS spectroscopy, we designed a new bambusuril derivative incorporating aromatic groups in its structure. Here we report preparation of xylylene-glycoluril macrocycles. Inspired by work of prof. Shimizu on aromatic-urea macrocycles3, we employed basic synthetic conditions instead of the acid catalyzed condensation. It afforded us with macrocycles of various sizes (Fig. 1), which were separated by reverse-phase flash chromatography. The conformational behavior of separated isomers of two-membered macrocycles were studied by temperature dependent NMR. The three-membered macrocycle was observed in a gas phase to bind anions.
ER -
LÍZAL, Tomáš a Vladimír ŠINDELÁŘ. Xylylene-Glycoluril Macrocycles. In \textit{53rd Advances in Organic, Bioorganic and Pharmaceutical Chemistry ''Liblice 2018'' 2-4 November 2018, Lázně Bělohrad, Czech Republic}. 2018.
|
