Resistive Pulse Sensing as Particle Counting and Sizing Method
in Microfluidic Systems: Designs and Applications Review

J 2019

Resistive Pulse Sensing as Particle Counting and Sizing Method in Microfluidic Systems: Designs and Applications Review

VÁCLAVEK, Tomáš; Jan PŘIKRYL and František FORET

Basic information

Original name

Resistive Pulse Sensing as Particle Counting and Sizing Method in Microfluidic Systems: Designs and Applications Review

Authors

VÁCLAVEK, Tomáš (203 Czech Republic, belonging to the institution); Jan PŘIKRYL (203 Czech Republic) and František FORET (203 Czech Republic)

Edition

Journal of separation science, Weinheim, WILEY-V C H VERLAG GMBH, 2019, 1615-9306

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10406 Analytical chemistry

Country of publisher

Germany

Confidentiality degree

is not subject to a state or trade secret

References:

Full Text

Impact factor

Impact factor: 2.878

RIV identification code

RIV/00216224:14310/19:00107226

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1002/jssc.201800978

UT WoS

000455258200023

EID Scopus

2-s2.0-85057974685

Keywords in English

bioanalysis;electrical impedance spectroscopy;microfluidics;single cell analysis

Abstract

In the original language

Resistive pulse sensing is a well-known and established method for counting and sizing particles in ionic solutions. Throughout its development the technique has been expanded from detection of biological cells to counting nanoparticles and viruses, and even registering individual molecules, e.g., nucleotides in nucleic acids. This technique combined with microfluidic or nanofluidic systems shows great potential for various bioanalytical applications, which were hardly possible before microfabrication gained the present broad adoption. In this review, we provide a comprehensive overview of microfluidic designs along with electrode arrangements with emphasis on applications focusing on bioanalysis and analysis of single cells that were reported within the past five years.

Links

GBP206/12/G014, research and development project

Name: Centrum pokročilých bioanalytických technologií

Cite

VÁCLAVEK, Tomáš; Jan PŘIKRYL and František FORET. Resistive Pulse Sensing as Particle Counting and Sizing Method in Microfluidic Systems: Designs and Applications Review. Journal of separation science. Weinheim: WILEY-V C H VERLAG GMBH, 2019, vol. 42, No 1, p. 445-457. ISSN 1615-9306. Available from: https://dx.doi.org/10.1002/jssc.201800978.

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   author = {Václavek, Tomáš and Přikryl, Jan and Foret, František},
   article_location = {Weinheim},
   article_number = {1},
   doi = {http://dx.doi.org/10.1002/jssc.201800978},
   keywords = {bioanalysis;electrical impedance spectroscopy;microfluidics;single cell analysis},
   language = {eng},
   issn = {1615-9306},
   journal = {Journal of separation science},
   title = {Resistive Pulse Sensing as Particle Counting and Sizing Method in Microfluidic Systems: Designs and Applications Review},
   url = {https://onlinelibrary.wiley.com/doi/epdf/10.1002/jssc.201800978},
   volume = {42},
   year = {2019}
}

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ID  - 1484698
AU  - Václavek, Tomáš - Přikryl, Jan - Foret, František
PY  - 2019
TI  - Resistive Pulse Sensing as Particle Counting and Sizing Method in Microfluidic Systems: Designs and Applications Review
JF  - Journal of separation science
VL  - 42
IS  - 1
SP  - 445-457
EP  - 445-457
PB  - WILEY-V C H VERLAG GMBH
SN  - 16159306
KW  - bioanalysis;electrical impedance spectroscopy;microfluidics;single cell analysis
UR  - https://onlinelibrary.wiley.com/doi/epdf/10.1002/jssc.201800978
L2  - https://onlinelibrary.wiley.com/doi/epdf/10.1002/jssc.201800978
N2  - Resistive pulse sensing is a well-known and established method for counting and sizing particles in ionic solutions. Throughout its development the technique has been expanded from detection of biological cells to counting nanoparticles and viruses, and even registering individual molecules, e.g., nucleotides in nucleic acids. This technique combined with microfluidic or nanofluidic systems shows great potential for various bioanalytical applications, which were hardly possible before microfabrication gained the present broad adoption. In this review, we provide a comprehensive overview of microfluidic designs along with electrode arrangements with emphasis on applications focusing on bioanalysis and analysis of single cells that were reported within the past five years.
ER  -

VÁCLAVEK, Tomáš; Jan PŘIKRYL and František FORET. Resistive Pulse Sensing as Particle Counting and Sizing Method in Microfluidic Systems: Designs and Applications Review. \textit{Journal of separation science}. Weinheim: WILEY-V C H VERLAG GMBH, 2019, vol.~42, No~1, p.~445-457. ISSN~1615-9306. Available from: https://dx.doi.org/10.1002/jssc.201800978.

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