a 2018

Assesment of Important Analytical Parameters of Peptest Immunoassay for its use in Diagnosis of Esophageal Reflux Disease

KONEČNÝ, Štefan, Jiří DOLINA, Pavol ĎURČ, Júlia LAČNÁ, Michal GREGUŠ et. al.

Basic information

Original name

Assesment of Important Analytical Parameters of Peptest Immunoassay for its use in Diagnosis of Esophageal Reflux Disease

Authors

KONEČNÝ, Štefan (703 Slovakia, belonging to the institution), Jiří DOLINA (203 Czech Republic, belonging to the institution), Pavol ĎURČ (703 Slovakia), Júlia LAČNÁ (703 Slovakia), Michal GREGUŠ (703 Slovakia), František FORET (203 Czech Republic), Jana SKŘIČKOVÁ (203 Czech Republic), Martina DOUBKOVÁ (203 Czech Republic), Dagmar KINDLOVÁ (203 Czech Republic), Eva POKOJOVÁ (203 Czech Republic) and Petr KUBÁŇ (203 Czech Republic)

Edition

Digestive Disease Week, Washington DC, USA, 2018

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30219 Gastroenterology and hepatology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14110/18:00106970

Organization unit

Faculty of Medicine

Keywords in English

GERD; extraesophageal reflux; pepsin; bile acids; noninvasive tests
Změněno: 10/2/2019 17:23, MUDr. Petr Litzman

Abstract

V originále

Introduction: Gastroesophageal reflux disease (GERD) can lead to esophageal and extraesophageal symptomatology. Extraesophageal reflux (EER) is a condition where refluxate penetrate above the upper esophageal sphincter into the oral cavity, pharynx, upper and lower respiratory tract. Prolonged or repeated exposure to gastric contents leads to mucosal damage and pathological changes. Experimental studies suggested that the damage caused by reflux is not only due to acidic nature of the refluxate, but is caused also by pepsin and bile acids

Links

NV17-31945A, research and development project
Name: Vývoj neinvazivní diagnostiky extraezofageálních projevů refluxní choroby jícnu