| HAMERS, Timo, Jessica LEGRADI, Nick ZWART, Foppe SMEDES, Jasperien DE WEERT, Evert-Jan VAN DEN BRANDHOF, Dik van DE MEENT a Dick DE ZWART. Time-Integrative Passive sampling combined with TOxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, roč. 64, December, s. 48-59. ISSN 1382-6689. Dostupné z: https://dx.doi.org/10.1016/j.etap.2018.09.005. |
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@article{1495625,
author = {Hamers, Timo and Legradi, Jessica and Zwart, Nick and Smedes, Foppe and de Weert, Jasperien and van den Brandhof, EvertandJan and de Meent, Dik van and de Zwart, Dick},
article_location = {AMSTERDAM},
article_number = {December},
doi = {http://dx.doi.org/10.1016/j.etap.2018.09.005},
keywords = {Speedisk; silicone rubber; in vitro bioassay; in vivo bioassay; species-sensitivity distribution (SSD); multiple substance potentially affected fraction of species (msPAF); priority compounds; River Meuse},
language = {eng},
issn = {1382-6689},
journal = {ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY},
title = {Time-Integrative Passive sampling combined with TOxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment},
url = {https://www.sciencedirect.com/science/article/pii/S1382668918303806?via%3Dihub},
volume = {64},
year = {2018}
}
TY - JOUR
ID - 1495625
AU - Hamers, Timo - Legradi, Jessica - Zwart, Nick - Smedes, Foppe - de Weert, Jasperien - van den Brandhof, Evert-Jan - de Meent, Dik van - de Zwart, Dick
PY - 2018
TI - Time-Integrative Passive sampling combined with TOxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment
JF - ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
VL - 64
IS - December
SP - 48-59
EP - 48-59
PB - ELSEVIER SCIENCE BV
SN - 13826689
KW - Speedisk
KW - silicone rubber
KW - in vitro bioassay
KW - in vivo bioassay
KW - species-sensitivity distribution (SSD)
KW - multiple substance potentially affected fraction of species (msPAF)
KW - priority compounds
KW - River Meuse
UR - https://www.sciencedirect.com/science/article/pii/S1382668918303806?via%3Dihub
L2 - https://www.sciencedirect.com/science/article/pii/S1382668918303806?via%3Dihub
N2 - This study aimed at demonstrating that effect-based monitoring with passive sampling followed by toxicity profiling is more protective and cost-effective than the current chemical water quality assessment strategy consisting of compound-by-compound chemical analysis of selected substances in grab samples. Passive samplers were deployed in the Dutch river delta and in WWTP effluents. Their extracts were tested in a battery of bioassays and chemically analyzed to obtain toxicity and chemical profiles, respectively. Chemical concentrations in water were retrieved from publicly available databases. Seven different strategies were used to interpret the chemical and toxicity profiles in terms of ecological risk. They all indicated that the river sampling locations were relatively clean. Chemical-based monitoring resulted for many substances in measurements below detection limit and could only explain < 20% of the observed in vitro toxicity. Effect-based monitoring yielded more informative conclusions as it allowed for ranking the sampling sites and for estimating a margin-of-exposure towards chronic effect ranges. Effect-based monitoring was also cheaper and more cost-effective (Le. yielding more information per euro spent). Based on its identified strengths, weaknesses, opportunities, and threats (SWOT), a future strategy for effect-based monitoring has been proposed.
ER -
HAMERS, Timo, Jessica LEGRADI, Nick ZWART, Foppe SMEDES, Jasperien DE WEERT, Evert-Jan VAN DEN BRANDHOF, Dik van DE MEENT a Dick DE ZWART. Time-Integrative Passive sampling combined with TOxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment. \textit{ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY}. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, roč.~64, December, s.~48-59. ISSN~1382-6689. Dostupné z: https://dx.doi.org/10.1016/j.etap.2018.09.005.
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