Detection of Chloroalkanes by Surface-Enhanced Raman
Spectroscopy in Microfluidic Chips

J 2018

Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips

PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA et. al.

Základní údaje

Originální název

Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips

Autoři

PILAT, Z. (203 Česká republika), M. KIZOVSKY (203 Česká republika), J. JEZEK (203 Česká republika), S. KRATKY (203 Česká republika), J. SOBOTA (203 Česká republika), Martin ŠILER (203 Česká republika), O. SAMEK (203 Česká republika), Tomáš BURYŠKA (203 Česká republika, domácí), Pavel VAŇÁČEK (203 Česká republika, domácí), Jiří DAMBORSKÝ (203 Česká republika, garant, domácí), Zbyněk PROKOP (203 Česká republika, domácí) a P. ZEMANEK (203 Česká republika)

Vydání

Sensors, Basel, MDPI AG, 2018, 1424-8220

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10306 Optics

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.031

Kód RIV

RIV/00216224:14310/18:00101751

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.3390/s18103212

UT WoS

000448661500040

Klíčová slova anglicky

surface enhanced Raman spectroscopy; microfluidics; Klarite 312; chloroalkane; 1; 2; 3-trichloropropane

Změněno: 23. 4. 2024 14:19, Mgr. Michal Petr

Anotace

V originále

Optofluidics, a research discipline combining optics with microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g., for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.

Návaznosti

GA16-07965S, projekt VaV

Název: Řízená evoluce dynamických elementů v enzymech s využitím mikrofluidních čipů

Investor: Grantová agentura ČR, Řízená evoluce dynamických elementů v enzymech s využitím mikrofluidních čipů

LM2015051, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX RI)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumná infrastruktura RECETOX

LO1214, projekt VaV

Název: Centrum pro výzkum toxických látek v prostředí (Akronym: RECETOX)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Centrum pro výzkum toxických látek v prostředí

Citovat

PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA, Martin ŠILER, O. SAMEK, Tomáš BURYŠKA, Pavel VAŇÁČEK, Jiří DAMBORSKÝ, Zbyněk PROKOP a P. ZEMANEK. Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips. Sensors. Basel: MDPI AG, 2018, roč. 18, č. 10, s. 1-18. ISSN 1424-8220. Dostupné z: https://dx.doi.org/10.3390/s18103212.

@article{1503339,
   author = {Pilat, Z. and Kizovsky, M. and Jezek, J. and Kratky, S. and Sobota, J. and Šiler, Martin and Samek, O. and Buryška, Tomáš and Vaňáček, Pavel and Damborský, Jiří and Prokop, Zbyněk and Zemanek, P.},
   article_location = {Basel},
   article_number = {10},
   doi = {http://dx.doi.org/10.3390/s18103212},
   keywords = {surface enhanced Raman spectroscopy; microfluidics; Klarite 312; chloroalkane; 1; 2; 3-trichloropropane},
   language = {eng},
   issn = {1424-8220},
   journal = {Sensors},
   title = {Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips},
   url = {https://loschmidt.chemi.muni.cz/peg/wp-content/uploads/2018/09/sensors-18-03212.pdf},
   volume = {18},
   year = {2018}
}

TY  - JOUR
ID  - 1503339
AU  - Pilat, Z. - Kizovsky, M. - Jezek, J. - Kratky, S. - Sobota, J. - Šiler, Martin - Samek, O. - Buryška, Tomáš - Vaňáček, Pavel - Damborský, Jiří - Prokop, Zbyněk - Zemanek, P.
PY  - 2018
TI  - Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips
JF  - Sensors
VL  - 18
IS  - 10
SP  - 1-18
EP  - 1-18
PB  - MDPI AG
SN  - 14248220
KW  - surface enhanced Raman spectroscopy
KW  - microfluidics
KW  - Klarite 312
KW  - chloroalkane
KW  - 1
KW  - 2
KW  - 3-trichloropropane
UR  - https://loschmidt.chemi.muni.cz/peg/wp-content/uploads/2018/09/sensors-18-03212.pdf
N2  - Optofluidics, a research discipline combining optics with microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g., for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.
ER  -

PILAT, Z., M. KIZOVSKY, J. JEZEK, S. KRATKY, J. SOBOTA, Martin ŠILER, O. SAMEK, Tomáš BURYŠKA, Pavel VAŇÁČEK, Jiří DAMBORSKÝ, Zbyněk PROKOP a P. ZEMANEK. Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips. \textit{Sensors}. Basel: MDPI AG, 2018, roč.~18, č.~10, s.~1-18. ISSN~1424-8220. Dostupné z: https://dx.doi.org/10.3390/s18103212.

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