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@proceedings{1503384,
author = {Hatina, J. and Kripnerova, M. and Parmar, H.S. and Houdek, Z. and Dvorak, P. and Houfkova, K. and Pesta, M. and Kuncova, J. and Šána, Jiří and Slabý, Ondřej},
booktitle = {25th Biennial Congress of the European Association for Cancer Research},
keywords = {soft tissue sarcoma; murine fibrosarcoma},
language = {eng},
title = {Identification of candidate genes underlying soft tissue sarcoma progression using a progression series of murine fibrosarcoma cell lines},
year = {2018}
}
TY - CONF
ID - 1503384
AU - Hatina, J. - Kripnerova, M. - Parmar, H.S. - Houdek, Z. - Dvorak, P. - Houfkova, K. - Pesta, M. - Kuncova, J. - Šána, Jiří - Slabý, Ondřej
PY - 2018
TI - Identification of candidate genes underlying soft tissue sarcoma progression using a progression series of murine fibrosarcoma cell lines
KW - soft tissue sarcoma
KW - murine fibrosarcoma
N2 - ntroduction Soft tissue sarcomas are known for their great variability in clinical behaviour, ranging from almost indolent lesions to rapidly metastasing tumours. Genes responsible for sarcoma progression have been poorly characterised by now. Towards this end, we established a unique single-background progression series of murine sarcoma cell lines, consisting of the slowly proliferating nonmotile and noninvasive cell line JUN-2, rapidly proliferating, motile and invasive cell line JUN-3, and the cell line JUN-2fos-3 that exhibits a unique transformation pattern, with little deregulation of cell growth and proliferation, but pronounced motility and invasiveness.
ER -
HATINA, J., M. KRIPNEROVA, H.S. PARMAR, Z. HOUDEK, P. DVORAK, K. HOUFKOVA, M. PESTA, J. KUNCOVA, Jiří ŠÁNA and Ondřej SLABÝ. Identification of candidate genes underlying soft tissue sarcoma progression using a progression series of murine fibrosarcoma cell lines. In \textit{25th Biennial Congress of the European Association for Cancer Research}. 2018. ISSN~2211-5463.
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