Comparative analysis of high butanol tolerance and production
in clostridia

J 2018

Comparative analysis of high butanol tolerance and production in clostridia

PATAKOVA, Petra, Jan KOLEK, Karel SEDLAR, Pavlina KOSCOVA, Barbora BRANSKA et. al.

Základní údaje

Originální název

Comparative analysis of high butanol tolerance and production in clostridia

Autoři

PATAKOVA, Petra (203 Česká republika, garant), Jan KOLEK (203 Česká republika), Karel SEDLAR (203 Česká republika), Pavlina KOSCOVA (203 Česká republika), Barbora BRANSKA (203 Česká republika), Kristyna KUPKOVA (203 Česká republika), Leona PAULOVA (203 Česká republika) a Ivo PROVAZNÍK (203 Česká republika, domácí)

Vydání

BIOTECHNOLOGY ADVANCES, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2018, 0734-9750

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 12.831

Kód RIV

RIV/00216224:14110/18:00106536

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.biotechadv.2017.12.004

UT WoS

000432104800013

Klíčová slova anglicky

Clostridium; ABE fermentation; Butanol tolerance; Butanol production; Genome mining; Transcriptomics

Štítky

14110515, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 3. 2019 09:40, Soňa Böhmová

Anotace

V originále

2016, was the 100 years anniversary from launching of the first industrial acetone-butanol-ethanol (ABE) microbial production process. Despite this long period and also revival of scientific interest in this fermentative process over the last 20 years, solventogenic clostridia, mainly Clostridium acetobutylicum, Clostridium beijerinckii, Clostridium saccharoperbutylacetonicum and Clostridium pasteurianum, still have most of their secrets. One such poorly understood mechanism is butanol tolerance, which seems to be one of the most significant bottlenecks obstructing industrial exploitation of the process because the maximum achievable butanol concentration is only about 21 g/L. This review describes all the known cellular responses elicited by butanol, such as modifications of cell membrane and cell wall, formation of stress proteins, extrusion of butanol by efflux pumps, response of regulatory pathways, and also maps both random and targeted mutations resulting in high butanol production phenotypes. As progress in the field is inseparably associated with emerging methods, enabling a deeper understanding of butanol tolerance and production, progress in these methods, including genome mining, RNA sequencing and constructing of genome scale models are also reviewed. In conclusion, a comparative analysis of both phenomena is presented and a theoretical relationship is described between butanol tolerance/high production and common features including efflux pump formation/activity, stress protein production, membrane modifications and biofilm growth.

Citovat

PATAKOVA, Petra, Jan KOLEK, Karel SEDLAR, Pavlina KOSCOVA, Barbora BRANSKA, Kristyna KUPKOVA, Leona PAULOVA a Ivo PROVAZNÍK. Comparative analysis of high butanol tolerance and production in clostridia. BIOTECHNOLOGY ADVANCES. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2018, roč. 36, č. 3, s. 721-738. ISSN 0734-9750. Dostupné z: https://dx.doi.org/10.1016/j.biotechadv.2017.12.004.

@article{1504231,
   author = {Patakova, Petra and Kolek, Jan and Sedlar, Karel and Koscova, Pavlina and Branska, Barbora and Kupkova, Kristyna and Paulova, Leona and Provazník, Ivo},
   article_location = {OXFORD},
   article_number = {3},
   doi = {http://dx.doi.org/10.1016/j.biotechadv.2017.12.004},
   keywords = {Clostridium; ABE fermentation; Butanol tolerance; Butanol production; Genome mining; Transcriptomics},
   language = {eng},
   issn = {0734-9750},
   journal = {BIOTECHNOLOGY ADVANCES},
   title = {Comparative analysis of high butanol tolerance and production in clostridia},
   volume = {36},
   year = {2018}
}

TY  - JOUR
ID  - 1504231
AU  - Patakova, Petra - Kolek, Jan - Sedlar, Karel - Koscova, Pavlina - Branska, Barbora - Kupkova, Kristyna - Paulova, Leona - Provazník, Ivo
PY  - 2018
TI  - Comparative analysis of high butanol tolerance and production in clostridia
JF  - BIOTECHNOLOGY ADVANCES
VL  - 36
IS  - 3
SP  - 721-738
EP  - 721-738
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 07349750
KW  - Clostridium
KW  - ABE fermentation
KW  - Butanol tolerance
KW  - Butanol production
KW  - Genome mining
KW  - Transcriptomics
N2  - 2016, was the 100 years anniversary from launching of the first industrial acetone-butanol-ethanol (ABE) microbial production process. Despite this long period and also revival of scientific interest in this fermentative process over the last 20 years, solventogenic clostridia, mainly Clostridium acetobutylicum, Clostridium beijerinckii, Clostridium saccharoperbutylacetonicum and Clostridium pasteurianum, still have most of their secrets. One such poorly understood mechanism is butanol tolerance, which seems to be one of the most significant bottlenecks obstructing industrial exploitation of the process because the maximum achievable butanol concentration is only about 21 g/L. This review describes all the known cellular responses elicited by butanol, such as modifications of cell membrane and cell wall, formation of stress proteins, extrusion of butanol by efflux pumps, response of regulatory pathways, and also maps both random and targeted mutations resulting in high butanol production phenotypes. As progress in the field is inseparably associated with emerging methods, enabling a deeper understanding of butanol tolerance and production, progress in these methods, including genome mining, RNA sequencing and constructing of genome scale models are also reviewed. In conclusion, a comparative analysis of both phenomena is presented and a theoretical relationship is described between butanol tolerance/high production and common features including efflux pump formation/activity, stress protein production, membrane modifications and biofilm growth.
ER  -

PATAKOVA, Petra, Jan KOLEK, Karel SEDLAR, Pavlina KOSCOVA, Barbora BRANSKA, Kristyna KUPKOVA, Leona PAULOVA a Ivo PROVAZNÍK. Comparative analysis of high butanol tolerance and production in clostridia. \textit{BIOTECHNOLOGY ADVANCES}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2018, roč.~36, č.~3, s.~721-738. ISSN~0734-9750. Dostupné z: https://dx.doi.org/10.1016/j.biotechadv.2017.12.004.

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