Quantitative myotonia assessment with a commercially available
dynamometer in myotonic dystrophy types 1 and 2

J 2019

Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2

HORÁKOVÁ, Magda, Tomáš HORÁK, Olesja PARMOVÁ, Josef BEDNAŘÍK, Stanislav VOHÁŇKA et. al.

Základní údaje

Originální název

Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2

Autoři

HORÁKOVÁ, Magda (203 Česká republika, garant, domácí), Tomáš HORÁK (203 Česká republika, domácí), Olesja PARMOVÁ (203 Česká republika, domácí), Josef BEDNAŘÍK (203 Česká republika, domácí) a Stanislav VOHÁŇKA (203 Česká republika, domácí)

Vydání

MUSCLE & NERVE, HOBOKEN, WILEY, 2019, 0148-639X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.505

Kód RIV

RIV/00216224:14110/19:00109475

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1002/mus.26401

UT WoS

000461232700012

Klíčová slova anglicky

muscle relaxation; muscle strength dynamometer; myotonia; myotonic dystrophy; outcome measure; warm-up

Štítky

14110221, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 27. 2. 2020 14:59, Mgr. Tereza Miškechová

Anotace

V originále

Introduction: The objective of this study was to develop a simple method for quantitative assessment of myotonia in patients with myotonic dystrophy type 1 (DM1) and DM2, to compare the myotonia severity, and to correlate this objective outcome with a subjective scale, the Myotonia Behaviour Scale (MBS). Methods: A commercially available dynamometer was used for all measurements. The relaxation time after voluntary contraction was measured in 20 patients with DM1, 25 patients with DM2, and 35 healthy controls. Results: The average relaxation time was 0.17 s in controls, 2.96 s in patients with DM1, and 0.4 s in patients with DM2. The correlation between relaxation time and MBS score was significant, 0.627 in patients with DM1 and 0.581 in patients with DM2. Discussion: Our method provides a valid and reliable quantitative measure of grip myotonia suitable as an outcome measure in clinical trials and as part of routine examinations to gather data on the natural history of myotonic disorders. Muscle Nerve 59:431-435, 2019

Návaznosti

MUNI/A/1072/2017, interní kód MU

Název: Diagnostika a patofyziologie neuropatické bolesti (Akronym: PNB)

Investor: Masarykova univerzita, Diagnostika a patofyziologie neuropatické bolesti, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

MUNI/A/1419/2018, interní kód MU

Název: Diagnostika a patofyziologie neuropatické bolesti (Akronym: PNB)

Investor: Masarykova univerzita, Diagnostika a patofyziologie neuropatické bolesti, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

HORÁKOVÁ, Magda, Tomáš HORÁK, Olesja PARMOVÁ, Josef BEDNAŘÍK a Stanislav VOHÁŇKA. Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2. MUSCLE & NERVE. HOBOKEN: WILEY, 2019, roč. 59, č. 4, s. 431-435. ISSN 0148-639X. Dostupné z: https://dx.doi.org/10.1002/mus.26401.

@article{1522136,
   author = {Horáková, Magda and Horák, Tomáš and Parmová, Olesja and Bednařík, Josef and Voháňka, Stanislav},
   article_location = {HOBOKEN},
   article_number = {4},
   doi = {http://dx.doi.org/10.1002/mus.26401},
   keywords = {muscle relaxation; muscle strength dynamometer; myotonia; myotonic dystrophy; outcome measure; warm-up},
   language = {eng},
   issn = {0148-639X},
   journal = {MUSCLE & NERVE},
   title = {Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2},
   url = {http://dx.doi.org/10.1002/mus.26401},
   volume = {59},
   year = {2019}
}

TY  - JOUR
ID  - 1522136
AU  - Horáková, Magda - Horák, Tomáš - Parmová, Olesja - Bednařík, Josef - Voháňka, Stanislav
PY  - 2019
TI  - Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2
JF  - MUSCLE & NERVE
VL  - 59
IS  - 4
SP  - 431-435
EP  - 431-435
PB  - WILEY
SN  - 0148639X
KW  - muscle relaxation
KW  - muscle strength dynamometer
KW  - myotonia
KW  - myotonic dystrophy
KW  - outcome measure
KW  - warm-up
UR  - http://dx.doi.org/10.1002/mus.26401
L2  - http://dx.doi.org/10.1002/mus.26401
N2  - Introduction: The objective of this study was to develop a simple method for quantitative assessment of myotonia in patients with myotonic dystrophy type 1 (DM1) and DM2, to compare the myotonia severity, and to correlate this objective outcome with a subjective scale, the Myotonia Behaviour Scale (MBS). Methods: A commercially available dynamometer was used for all measurements. The relaxation time after voluntary contraction was measured in 20 patients with DM1, 25 patients with DM2, and 35 healthy controls. Results: The average relaxation time was 0.17 s in controls, 2.96 s in patients with DM1, and 0.4 s in patients with DM2. The correlation between relaxation time and MBS score was significant, 0.627 in patients with DM1 and 0.581 in patients with DM2. Discussion: Our method provides a valid and reliable quantitative measure of grip myotonia suitable as an outcome measure in clinical trials and as part of routine examinations to gather data on the natural history of myotonic disorders. Muscle Nerve 59:431-435, 2019
ER  -

HORÁKOVÁ, Magda, Tomáš HORÁK, Olesja PARMOVÁ, Josef BEDNAŘÍK a Stanislav VOHÁŇKA. Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2. \textit{MUSCLE \&{}amp; NERVE}. HOBOKEN: WILEY, 2019, roč.~59, č.~4, s.~431-435. ISSN~0148-639X. Dostupné z: https://dx.doi.org/10.1002/mus.26401.

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