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@article{1531316,
author = {Vaníček, Jiří and Cimflová, Petra and Bulik, Martin and Jarkovský, Jiří and Prelecová, Veronika and Szeder, Viktor and Volný, Ondřej},
article_location = {AMSTERDAM},
article_number = {4},
doi = {http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.041},
keywords = {Mechanical thrombectomy; CT perfusion; RAPID; single-centre experience},
language = {eng},
issn = {1052-3057},
journal = {JOURNAL OF STROKE & CEREBROVASCULAR DISEASES},
title = {Single-Centre Experience with Patients Selection for Mechanical Thrombectomy Based on Automated Computed Tomography Perfusion Analysis-A Comparison with Computed TomographyCT Perfusion Thrombectomy Trials},
url = {http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.041},
volume = {28},
year = {2019}
}
TY - JOUR
ID - 1531316
AU - Vaníček, Jiří - Cimflová, Petra - Bulik, Martin - Jarkovský, Jiří - Prelecová, Veronika - Szeder, Viktor - Volný, Ondřej
PY - 2019
TI - Single-Centre Experience with Patients Selection for Mechanical Thrombectomy Based on Automated Computed Tomography Perfusion Analysis-A Comparison with Computed TomographyCT Perfusion Thrombectomy Trials
JF - JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
VL - 28
IS - 4
SP - 1085-1092
EP - 1085-1092
PB - ELSEVIER SCIENCE BV
SN - 10523057
KW - Mechanical thrombectomy
KW - CT perfusion
KW - RAPID
KW - single-centre experience
UR - http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.041
L2 - http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.041
N2 - Background: In randomized clinical trials, mechanical thrombectomy (MT) was proved to be a highly effective treatment of acute ischemic stroke which improved clinical outcomes. Some of the trials used automated computed tomography perfusion (CTP) analysis for selection of participants. We present a single-center experience with CTP selection and comparison with CTP trials. Methods: Data of consecutive MT patients (from January 2016 to December 2017) were retrospectively reviewed. All patients with multiphase CT angiography confirmed the presence of anterior circulation large vessel occlusion/s in the intracranial internal carotid artery and/or middle cerebral artery (M1 orM2) and with admission brain CTP analyzed by RAPID software were included into the analysis. Results: Sixty-two patients fulfilled the inclusion criteria (mean age was 70.1 +/- 13.6 years, females 48.5%). At baseline, National Institutes of Health Stroke Scale score was 16 (IQR = 13-20), Alberta Stroke Program Early CT Score (ASPECTS) was 8 (IQR = 7-9), CTP core volume was 20 mL (IQR = 2-36), and CTP penumbra volume was 145.5 mL (IQR = 107-184). Time from stroke onset to imaging was 1 hour 32 minutes, time from stroke onset to reperfusion was 3 hours 50minutes, and median time from CT to reperfusion was 1 hour 56 minutes. Modified thrombolysis in cerebral infarction 2b/3 was achieved in 42 patients (67.7%). Twenty-three patients (37%) had modified Rankin scale 0-2 at 90 days. Conclusions: Our analysis of CTP-selected patients for MT supports clinical applicability of automated CTP analysis into everyday clinical practice.
ER -
VANÍČEK, Jiří, Petra CIMFLOVÁ, Martin BULIK, Jiří JARKOVSKÝ, Veronika PRELECOVÁ, Viktor SZEDER a Ondřej VOLNÝ. Single-Centre Experience with Patients Selection for Mechanical Thrombectomy Based on Automated Computed Tomography Perfusion Analysis-A Comparison with Computed TomographyCT Perfusion Thrombectomy Trials. \textit{JOURNAL OF STROKE \&{}amp; CEREBROVASCULAR DISEASES}. AMSTERDAM: ELSEVIER SCIENCE BV, 2019, roč.~28, č.~4, s.~1085-1092. ISSN~1052-3057. Dostupné z: https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.041.
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