Do lumbar magnetic resonance imaging changes predict
neuropathic pain in patients with chronic non-specific low back
pain?

J 2019

Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

VAGASKÁ, Eva, Alexandra LITAVCOVÁ, Iva ŠROTOVÁ, Eva VLČKOVÁ, Miloš KEŘKOVSKÝ et. al.

Základní údaje

Originální název

Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

Autoři

VAGASKÁ, Eva (703 Slovensko, domácí), Alexandra LITAVCOVÁ (703 Slovensko, domácí), Iva ŠROTOVÁ (203 Česká republika, domácí), Eva VLČKOVÁ (203 Česká republika, domácí), Miloš KEŘKOVSKÝ (203 Česká republika, domácí), Jiří JARKOVSKÝ (203 Česká republika, domácí), Josef BEDNAŘÍK (203 Česká republika, domácí) a Blanka ADAMOVÁ (203 Česká republika, garant, domácí)

Vydání

Medicine, Philadelphia, Lippincott Williams & Wilkins, 2019, 0025-7974

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.552

Kód RIV

RIV/00216224:14110/19:00109783

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1097/MD.0000000000015377

UT WoS

000467337400079

Klíčová slova anglicky

DN4; low back pain; magnetic resonance imaging; neuropathic pain

Štítky

110216, 110221, 14110216, 14110221, 14119612, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 3. 2020 22:20, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP -female sex (odds ratio [OR]=11.9) and a mean pain intensity of >= 4.5 in the previous 4 weeks (OR=13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP.

Návaznosti

MUNI/A/1072/2017, interní kód MU

Název: Diagnostika a patofyziologie neuropatické bolesti (Akronym: PNB)

Investor: Masarykova univerzita, Diagnostika a patofyziologie neuropatické bolesti, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

MUNI/A/1419/2018, interní kód MU

Název: Diagnostika a patofyziologie neuropatické bolesti (Akronym: PNB)

Investor: Masarykova univerzita, Diagnostika a patofyziologie neuropatické bolesti, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

ROZV/24/LF/2018, interní kód MU

Název: LF - Příspěvek na IP 2108

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, LF - Příspěvek na IP 2108, Interní rozvojové projekty

Citovat

VAGASKÁ, Eva, Alexandra LITAVCOVÁ, Iva ŠROTOVÁ, Eva VLČKOVÁ, Miloš KEŘKOVSKÝ, Jiří JARKOVSKÝ, Josef BEDNAŘÍK a Blanka ADAMOVÁ. Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain? Medicine. Philadelphia: Lippincott Williams & Wilkins, 2019, roč. 98, č. 17, s. 1-9. ISSN 0025-7974. Dostupné z: https://dx.doi.org/10.1097/MD.0000000000015377.

@article{1535325,
   author = {Vagaská, Eva and Litavcová, Alexandra and Šrotová, Iva and Vlčková, Eva and Keřkovský, Miloš and Jarkovský, Jiří and Bednařík, Josef and Adamová, Blanka},
   article_location = {Philadelphia},
   article_number = {17},
   doi = {http://dx.doi.org/10.1097/MD.0000000000015377},
   keywords = {DN4; low back pain; magnetic resonance imaging; neuropathic pain},
   language = {eng},
   issn = {0025-7974},
   journal = {Medicine},
   title = {Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?},
   url = {https://journals.lww.com/md-journal/Fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx},
   volume = {98},
   year = {2019}
}

TY  - JOUR
ID  - 1535325
AU  - Vagaská, Eva - Litavcová, Alexandra - Šrotová, Iva - Vlčková, Eva - Keřkovský, Miloš - Jarkovský, Jiří - Bednařík, Josef - Adamová, Blanka
PY  - 2019
TI  - Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?
JF  - Medicine
VL  - 98
IS  - 17
SP  - 1-9
EP  - 1-9
PB  - Lippincott Williams & Wilkins
SN  - 00257974
KW  - DN4
KW  - low back pain
KW  - magnetic resonance imaging
KW  - neuropathic pain
UR  - https://journals.lww.com/md-journal/Fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx
L2  - https://journals.lww.com/md-journal/Fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx
N2  - The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP -female sex (odds ratio [OR]=11.9) and a mean pain intensity of >= 4.5 in the previous 4 weeks (OR=13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP.
ER  -

VAGASKÁ, Eva, Alexandra LITAVCOVÁ, Iva ŠROTOVÁ, Eva VLČKOVÁ, Miloš KEŘKOVSKÝ, Jiří JARKOVSKÝ, Josef BEDNAŘÍK a Blanka ADAMOVÁ. Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain? \textit{Medicine}. Philadelphia: Lippincott Williams \&{} Wilkins, 2019, roč.~98, č.~17, s.~1-9. ISSN~0025-7974. Dostupné z: https://dx.doi.org/10.1097/MD.0000000000015377.

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