Impact of drugs on venous thromboembolism risk in surgical
patients

J 2019

Impact of drugs on venous thromboembolism risk in surgical patients

KOVACIC, Alenka Premuš Marušič, Martin CAPRNDA, Aleš MRHAR, Peter KUBATKA, Igor LOCATELLI et. al.

Základní údaje

Originální název

Impact of drugs on venous thromboembolism risk in surgical patients

Autoři

KOVACIC, Alenka Premuš Marušič (705 Slovinsko), Martin CAPRNDA (703 Slovensko), Aleš MRHAR (705 Slovinsko), Peter KUBATKA (703 Slovensko), Igor LOCATELLI (705 Slovinsko), Barbora ZOLAKOVA (703 Slovensko), Ludovit GASPAR (703 Slovensko), Robert PROSECKÝ (203 Česká republika), Peter KRUŽLIAK (703 Slovensko, domácí), Robert STAFFA (203 Česká republika, domácí), Luis RODRIGO (724 Španělsko), Jozef RADONAK (703 Slovensko) a Danijel PETROVIC (705 Slovinsko)

Vydání

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, HEIDELBERG, SPRINGER HEIDELBERG, 2019, 0031-6970

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30212 Surgery

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.641

Kód RIV

RIV/00216224:14110/19:00108494

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s00228-019-02636-x

UT WoS

000469367900002

Klíčová slova anglicky

Venous thromboembolism; Analgesics; Diuretics; Antidepressants; Antipsychotics; Oral contraceptives; Surgery; Bridging anticoagulation; Transfusion; Thromboprophylaxis

Štítky

14110121, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 7. 2019 15:40, Soňa Böhmová

Anotace

V originále

PurposeThis review focuses on the most common drugs administered to surgical patients during the perioperative period that affect the risk of venous thromboembolism (VTE).ResultsAmong analgesics, the risk of VTE is increased in patients treated with diclofenac, ibuprofen, and rofecoxib, but not naproxen, while metamizole can confer a protective effect. The relationship between sedatives and VTE has not been sufficiently studied. Tricyclic antidepressants, low-potency serotonin reuptake inhibitors, and antipsychotics have been associated with increased risk of VTE. The use of diuretics in the perioperative period is poorly researched; however, hyponatremia is considered a risk factor. Other factors that may influence the risk of VTE include bridging anticoagulation, allogeneic transfusion, and hemostatic management before surgery. Pharmacotherapy for HIV or cancer may also increase VTE risk.ConclusionIncreased monitoring for VTE is therefore advisable in surgical patients and those receiving antipsychotics, antidepressants, diuretics, or analgesics.

Návaznosti

NV15-33437A, projekt VaV

Název: Vliv edukace na vybrané psychosomatické faktory u pacientů indikovaných k implantaci cévní protézy

Citovat

KOVACIC, Alenka Premuš Marušič, Martin CAPRNDA, Aleš MRHAR, Peter KUBATKA, Igor LOCATELLI, Barbora ZOLAKOVA, Ludovit GASPAR, Robert PROSECKÝ, Peter KRUŽLIAK, Robert STAFFA, Luis RODRIGO, Jozef RADONAK a Danijel PETROVIC. Impact of drugs on venous thromboembolism risk in surgical patients. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. HEIDELBERG: SPRINGER HEIDELBERG, 2019, roč. 75, č. 6, s. 751-767. ISSN 0031-6970. Dostupné z: https://dx.doi.org/10.1007/s00228-019-02636-x.

@article{1545961,
   author = {Kovacic, Alenka Premuš Marušič and Caprnda, Martin and Mrhar, Aleš and Kubatka, Peter and Locatelli, Igor and Zolakova, Barbora and Gaspar, Ludovit and Prosecký, Robert and Kružliak, Peter and Staffa, Robert and Rodrigo, Luis and Radonak, Jozef and Petrovic, Danijel},
   article_location = {HEIDELBERG},
   article_number = {6},
   doi = {http://dx.doi.org/10.1007/s00228-019-02636-x},
   keywords = {Venous thromboembolism; Analgesics; Diuretics; Antidepressants; Antipsychotics; Oral contraceptives; Surgery; Bridging anticoagulation; Transfusion; Thromboprophylaxis},
   language = {eng},
   issn = {0031-6970},
   journal = {EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY},
   title = {Impact of drugs on venous thromboembolism risk in surgical patients},
   url = {http://dx.doi.org/10.1007/s00228-019-02636-x},
   volume = {75},
   year = {2019}
}

TY  - JOUR
ID  - 1545961
AU  - Kovacic, Alenka Premuš Marušič - Caprnda, Martin - Mrhar, Aleš - Kubatka, Peter - Locatelli, Igor - Zolakova, Barbora - Gaspar, Ludovit - Prosecký, Robert - Kružliak, Peter - Staffa, Robert - Rodrigo, Luis - Radonak, Jozef - Petrovic, Danijel
PY  - 2019
TI  - Impact of drugs on venous thromboembolism risk in surgical patients
JF  - EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
VL  - 75
IS  - 6
SP  - 751-767
EP  - 751-767
PB  - SPRINGER HEIDELBERG
SN  - 00316970
KW  - Venous thromboembolism
KW  - Analgesics
KW  - Diuretics
KW  - Antidepressants
KW  - Antipsychotics
KW  - Oral contraceptives
KW  - Surgery
KW  - Bridging anticoagulation
KW  - Transfusion
KW  - Thromboprophylaxis
UR  - http://dx.doi.org/10.1007/s00228-019-02636-x
L2  - http://dx.doi.org/10.1007/s00228-019-02636-x
N2  - PurposeThis review focuses on the most common drugs administered to surgical patients during the perioperative period that affect the risk of venous thromboembolism (VTE).ResultsAmong analgesics, the risk of VTE is increased in patients treated with diclofenac, ibuprofen, and rofecoxib, but not naproxen, while metamizole can confer a protective effect. The relationship between sedatives and VTE has not been sufficiently studied. Tricyclic antidepressants, low-potency serotonin reuptake inhibitors, and antipsychotics have been associated with increased risk of VTE. The use of diuretics in the perioperative period is poorly researched; however, hyponatremia is considered a risk factor. Other factors that may influence the risk of VTE include bridging anticoagulation, allogeneic transfusion, and hemostatic management before surgery. Pharmacotherapy for HIV or cancer may also increase VTE risk.ConclusionIncreased monitoring for VTE is therefore advisable in surgical patients and those receiving antipsychotics, antidepressants, diuretics, or analgesics.
ER  -

KOVACIC, Alenka Premuš Marušič, Martin CAPRNDA, Aleš MRHAR, Peter KUBATKA, Igor LOCATELLI, Barbora ZOLAKOVA, Ludovit GASPAR, Robert PROSECKÝ, Peter KRUŽLIAK, Robert STAFFA, Luis RODRIGO, Jozef RADONAK a Danijel PETROVIC. Impact of drugs on venous thromboembolism risk in surgical patients. \textit{EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY}. HEIDELBERG: SPRINGER HEIDELBERG, 2019, roč.~75, č.~6, s.~751-767. ISSN~0031-6970. Dostupné z: https://dx.doi.org/10.1007/s00228-019-02636-x.

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