ŘEHULKA, Pavel, Jan CIMBALNIK, Martin PAIL, Jan CHRASTINA, Markéta HERMANOVÁ a Milan BRÁZDIL. Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. Clinical Neurophysiology. Clare: Elsevier Ireland, 2019, roč. 130, č. 7, s. 1151-1159. ISSN 1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2019.03.026. |
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@article{1546028, author = {Řehulka, Pavel and Cimbalnik, Jan and Pail, Martin and Chrastina, Jan and Hermanová, Markéta and Brázdil, Milan}, article_location = {Clare}, article_number = {7}, doi = {http://dx.doi.org/10.1016/j.clinph.2019.03.026}, keywords = {High frequency oscillations; Hippocampus; Hippocampal sclerosis; Temporal lobe epilepsy; Bitemporal epilepsy}, language = {eng}, issn = {1388-2457}, journal = {Clinical Neurophysiology}, title = {Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy}, url = {http://dx.doi.org/10.1016/j.clinph.2019.03.026}, volume = {130}, year = {2019} }
TY - JOUR ID - 1546028 AU - Řehulka, Pavel - Cimbalnik, Jan - Pail, Martin - Chrastina, Jan - Hermanová, Markéta - Brázdil, Milan PY - 2019 TI - Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy JF - Clinical Neurophysiology VL - 130 IS - 7 SP - 1151-1159 EP - 1151-1159 PB - Elsevier Ireland SN - 13882457 KW - High frequency oscillations KW - Hippocampus KW - Hippocampal sclerosis KW - Temporal lobe epilepsy KW - Bitemporal epilepsy UR - http://dx.doi.org/10.1016/j.clinph.2019.03.026 L2 - http://dx.doi.org/10.1016/j.clinph.2019.03.026 N2 - Objective: The main aim of this study was to investigate the potential differences in terms of interictal high frequency oscillations (HFOs) between both hippocampi in unilateral (U-MTLE) and bilateral mesial temporal lobe epilepsy (B-MTLE). Methods: Sixteen patients with MTLE underwent bilateral hippocampal depth electrode implantation as part of epilepsy surgery evaluation. Interictal HFOs were detected automatically. The analyses entail comparisons of the rates and spatial distributions of ripples and fast ripples (FR) in hippocampi and amygdalae, with respect to the eventual finding of hippocampal sclerosis (HS). Results: In U-MTLE, higher ripple and FR rates were found in the hippocampi ipsilateral to the seizure onset than in the contralateral hippocampi. Non-epileptic hippocampi in U-MTLE were distinguished by significantly lower ripple rate than in the remaining analyzed hippocampi. There were not differences between the hippocampi in B-MTLE. In the hippocampi with proven HS, higher FR rates were observed in the ventral than in the dorsal parts. Conclusions: Non-epileptic hippocampi in U-MTLE demonstrated significantly lower ripple rates than those epileptic in U-MTLE and B-MTLE. Significance: Low interictal HFO occurrence might be considered as a marker of the non-epileptic hippocampi in MTLE. (C) 2019 Published by Elsevier B.V. on behalf of International Federation of Clinical Neurophysiology. ER -
ŘEHULKA, Pavel, Jan CIMBALNIK, Martin PAIL, Jan CHRASTINA, Markéta HERMANOVÁ a Milan BRÁZDIL. Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. \textit{Clinical Neurophysiology}. Clare: Elsevier Ireland, 2019, roč.~130, č.~7, s.~1151-1159. ISSN~1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2019.03.026.
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