Hippocampal high frequency oscillations in unilateral and
bilateral mesial temporal lobe epilepsy

J 2019

Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy

ŘEHULKA, Pavel, Jan CIMBALNIK, Martin PAIL, Jan CHRASTINA, Markéta HERMANOVÁ et. al.

Základní údaje

Originální název

Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy

Autoři

ŘEHULKA, Pavel (203 Česká republika, garant, domácí), Jan CIMBALNIK (203 Česká republika), Martin PAIL (203 Česká republika, domácí), Jan CHRASTINA (203 Česká republika, domácí), Markéta HERMANOVÁ (203 Česká republika, domácí) a Milan BRÁZDIL (203 Česká republika, domácí)

Vydání

Clinical Neurophysiology, Clare, Elsevier Ireland, 2019, 1388-2457

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.214

Kód RIV

RIV/00216224:14110/19:00110199

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.clinph.2019.03.026

UT WoS

000469338500008

Klíčová slova anglicky

High frequency oscillations; Hippocampus; Hippocampal sclerosis; Temporal lobe epilepsy; Bitemporal epilepsy

Štítky

14110112, 14110127, 14110131, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 3. 2020 22:19, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

Objective: The main aim of this study was to investigate the potential differences in terms of interictal high frequency oscillations (HFOs) between both hippocampi in unilateral (U-MTLE) and bilateral mesial temporal lobe epilepsy (B-MTLE). Methods: Sixteen patients with MTLE underwent bilateral hippocampal depth electrode implantation as part of epilepsy surgery evaluation. Interictal HFOs were detected automatically. The analyses entail comparisons of the rates and spatial distributions of ripples and fast ripples (FR) in hippocampi and amygdalae, with respect to the eventual finding of hippocampal sclerosis (HS). Results: In U-MTLE, higher ripple and FR rates were found in the hippocampi ipsilateral to the seizure onset than in the contralateral hippocampi. Non-epileptic hippocampi in U-MTLE were distinguished by significantly lower ripple rate than in the remaining analyzed hippocampi. There were not differences between the hippocampi in B-MTLE. In the hippocampi with proven HS, higher FR rates were observed in the ventral than in the dorsal parts. Conclusions: Non-epileptic hippocampi in U-MTLE demonstrated significantly lower ripple rates than those epileptic in U-MTLE and B-MTLE. Significance: Low interictal HFO occurrence might be considered as a marker of the non-epileptic hippocampi in MTLE. (C) 2019 Published by Elsevier B.V. on behalf of International Federation of Clinical Neurophysiology.

Návaznosti

ROZV/24/LF/2018, interní kód MU

Název: LF - Příspěvek na IP 2108

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, LF - Příspěvek na IP 2108, Interní rozvojové projekty

Citovat

ŘEHULKA, Pavel, Jan CIMBALNIK, Martin PAIL, Jan CHRASTINA, Markéta HERMANOVÁ a Milan BRÁZDIL. Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. Clinical Neurophysiology. Clare: Elsevier Ireland, 2019, roč. 130, č. 7, s. 1151-1159. ISSN 1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2019.03.026.

@article{1546028,
   author = {Řehulka, Pavel and Cimbalnik, Jan and Pail, Martin and Chrastina, Jan and Hermanová, Markéta and Brázdil, Milan},
   article_location = {Clare},
   article_number = {7},
   doi = {http://dx.doi.org/10.1016/j.clinph.2019.03.026},
   keywords = {High frequency oscillations; Hippocampus; Hippocampal sclerosis; Temporal lobe epilepsy; Bitemporal epilepsy},
   language = {eng},
   issn = {1388-2457},
   journal = {Clinical Neurophysiology},
   title = {Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy},
   url = {http://dx.doi.org/10.1016/j.clinph.2019.03.026},
   volume = {130},
   year = {2019}
}

TY  - JOUR
ID  - 1546028
AU  - Řehulka, Pavel - Cimbalnik, Jan - Pail, Martin - Chrastina, Jan - Hermanová, Markéta - Brázdil, Milan
PY  - 2019
TI  - Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy
JF  - Clinical Neurophysiology
VL  - 130
IS  - 7
SP  - 1151-1159
EP  - 1151-1159
PB  - Elsevier Ireland
SN  - 13882457
KW  - High frequency oscillations
KW  - Hippocampus
KW  - Hippocampal sclerosis
KW  - Temporal lobe epilepsy
KW  - Bitemporal epilepsy
UR  - http://dx.doi.org/10.1016/j.clinph.2019.03.026
L2  - http://dx.doi.org/10.1016/j.clinph.2019.03.026
N2  - Objective: The main aim of this study was to investigate the potential differences in terms of interictal high frequency oscillations (HFOs) between both hippocampi in unilateral (U-MTLE) and bilateral mesial temporal lobe epilepsy (B-MTLE). Methods: Sixteen patients with MTLE underwent bilateral hippocampal depth electrode implantation as part of epilepsy surgery evaluation. Interictal HFOs were detected automatically. The analyses entail comparisons of the rates and spatial distributions of ripples and fast ripples (FR) in hippocampi and amygdalae, with respect to the eventual finding of hippocampal sclerosis (HS). Results: In U-MTLE, higher ripple and FR rates were found in the hippocampi ipsilateral to the seizure onset than in the contralateral hippocampi. Non-epileptic hippocampi in U-MTLE were distinguished by significantly lower ripple rate than in the remaining analyzed hippocampi. There were not differences between the hippocampi in B-MTLE. In the hippocampi with proven HS, higher FR rates were observed in the ventral than in the dorsal parts. Conclusions: Non-epileptic hippocampi in U-MTLE demonstrated significantly lower ripple rates than those epileptic in U-MTLE and B-MTLE. Significance: Low interictal HFO occurrence might be considered as a marker of the non-epileptic hippocampi in MTLE. (C) 2019 Published by Elsevier B.V. on behalf of International Federation of Clinical Neurophysiology.
ER  -

ŘEHULKA, Pavel, Jan CIMBALNIK, Martin PAIL, Jan CHRASTINA, Markéta HERMANOVÁ a Milan BRÁZDIL. Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy. \textit{Clinical Neurophysiology}. Clare: Elsevier Ireland, 2019, roč.~130, č.~7, s.~1151-1159. ISSN~1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2019.03.026.

Podrobný výpis o publikaci