Imaging of Bronchial Pathology in Antibody Deficiency: Data
from the European Chest CT Group

J 2019

Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group

SCHUTZ, Katharina, Diana ALECSANDRU, Bodo GRIMBACHER, Jamanda HADDOCK, Annemarie BRUINING et. al.

Základní údaje

Originální název

Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group

Autoři

SCHUTZ, Katharina (276 Německo), Diana ALECSANDRU (826 Velká Británie a Severní Irsko), Bodo GRIMBACHER (276 Německo), Jamanda HADDOCK (826 Velká Británie a Severní Irsko), Annemarie BRUINING (528 Nizozemské království), Gertjan DRIESSEN (528 Nizozemské království), Esther DE VRIES (528 Nizozemské království), Peter M. VAN HAGEN, Ieneke HARTMANN (528 Nizozemské království), Francesco FRAIOLI (380 Itálie), Cinzia MILITO (380 Itálie), Milica MITREVSKI (380 Itálie), Isabella QUINTI (380 Itálie), Goffredo SERRA (380 Itálie), Peter KELLEHER (826 Velká Británie a Severní Irsko), Michael LOEBINGER (826 Velká Británie a Severní Irsko), Jiří LITZMAN (203 Česká republika, domácí), Věra POSTRÁNECKÁ (203 Česká republika), Vojtěch THON (203 Česká republika, garant, domácí), Judith BABAR (826 Velká Británie a Severní Irsko), Alison M. CONDLIFFE (826 Velká Británie a Severní Irsko), Andrew EXLEY (826 Velká Británie a Severní Irsko), Dinakantha KUMARARATNE (826 Velká Británie a Severní Irsko), Nick SCREATON (826 Velká Británie a Severní Irsko), Alison JONES (826 Velká Británie a Severní Irsko), Maria P. BONDIONI (380 Itálie), Vassilios LOUGARIS (380 Itálie), Alessandro PLEBANI (380 Itálie), Annarosa SORESINA (380 Itálie), Cesare SIRIGNANO (380 Itálie), Giuseppe SPADARO (380 Itálie), Nermeen GALAL (818 Egypt), Luis I. GONZALEZ-GRANADO (724 Španělsko), Sabine DETTMER (276 Německo), Robert STIRLING (36 Austrálie), Helen CHAPEL (826 Velká Británie a Severní Irsko), Mary LUCAS (826 Velká Británie a Severní Irsko), Smita PATEL (826 Velká Británie a Severní Irsko), Claire-Michele FARBER (56 Belgie), Isabelle MEYTS (56 Belgie), Arpan K. BANERJEE (826 Velká Británie a Severní Irsko), Scott HACKETT (826 Velká Británie a Severní Irsko), John R. HURST (826 Velká Británie a Severní Irsko), Klaus WARNATZ (276 Německo), Benjamin GATHMANN (276 Německo) a Ulrich BAUMANN (276 Německo)

Vydání

Journal of Clinical Immunology, New York, Springer, 2019, 0271-9142

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30102 Immunology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.780

Kód RIV

RIV/00216224:14110/19:00110433

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s10875-018-0577-9

UT WoS

000458867500011

Klíčová slova anglicky

Chest CT; CVID; primary antibody deficiency; bronchiectasis; bronchial pathology

Štítky

14110114, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 1. 2020 07:03, Mgr. Tereza Miškechová

Anotace

V originále

Studies of chest computed tomography (CT) in patients with primary antibody deficiency syndromes (ADS) suggest a broad range of bronchial pathology. However, there are as yet no multicentre studies to assess the variety of bronchial pathology in this patient group. One of the underlying reasons is the lack of a consensus methodology, a prerequisite to jointly document chest CT findings. We aimed to establish an international platform for the evaluation of bronchial pathology as assessed by chest CT and to describe the range of bronchial pathologies in patients with antibody deficiency. Ffteen immunodeficiency centres from 9 countries evaluated chest CT scans of patients with ADS using a predefined list of potential findings including an extent score for bronchiectasis. Data of 282 patients with ADS were collected. Patients with common variable immunodeficiency disorders (CVID) comprised the largest subgroup (232 patients, 82.3%). Eighty percent of CVID patients had radiological evidence of bronchial pathology including bronchiectasis in 61%, bronchial wall thickening in 44% and mucus plugging in 29%. Bronchiectasis was detected in 44% of CVID patients aged less than 20years. Cough was a better predictor for bronchiectasis than spirometry values. Delay of diagnosis as well as duration of disease correlated positively with presence of bronchiectasis. The use of consensus diagnostic criteria and a pre-defined list of bronchial pathologies allows for comparison of chest CT data in multicentre studies. Our data suggest a high prevalence of bronchial pathology in CVID due to late diagnosis or duration of disease.

Návaznosti

EF15_003/0000469, projekt VaV

Název: Cetocoen Plus

Citovat

SCHUTZ, Katharina, Diana ALECSANDRU, Bodo GRIMBACHER, Jamanda HADDOCK, Annemarie BRUINING, Gertjan DRIESSEN, Esther DE VRIES, Peter M. VAN HAGEN, Ieneke HARTMANN, Francesco FRAIOLI, Cinzia MILITO, Milica MITREVSKI, Isabella QUINTI, Goffredo SERRA, Peter KELLEHER, Michael LOEBINGER, Jiří LITZMAN, Věra POSTRÁNECKÁ, Vojtěch THON, Judith BABAR, Alison M. CONDLIFFE, Andrew EXLEY, Dinakantha KUMARARATNE, Nick SCREATON, Alison JONES, Maria P. BONDIONI, Vassilios LOUGARIS, Alessandro PLEBANI, Annarosa SORESINA, Cesare SIRIGNANO, Giuseppe SPADARO, Nermeen GALAL, Luis I. GONZALEZ-GRANADO, Sabine DETTMER, Robert STIRLING, Helen CHAPEL, Mary LUCAS, Smita PATEL, Claire-Michele FARBER, Isabelle MEYTS, Arpan K. BANERJEE, Scott HACKETT, John R. HURST, Klaus WARNATZ, Benjamin GATHMANN a Ulrich BAUMANN. Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. Journal of Clinical Immunology. New York: Springer, 2019, roč. 39, č. 1, s. 45-54. ISSN 0271-9142. Dostupné z: https://dx.doi.org/10.1007/s10875-018-0577-9.

@article{1549656,
   author = {Schutz, Katharina and Alecsandru, Diana and Grimbacher, Bodo and Haddock, Jamanda and Bruining, Annemarie and Driessen, Gertjan and de Vries, Esther and van Hagen, Peter M. and Hartmann, Ieneke and Fraioli, Francesco and Milito, Cinzia and Mitrevski, Milica and Quinti, Isabella and Serra, Goffredo and Kelleher, Peter and Loebinger, Michael and Litzman, Jiří and Postránecká, Věra and Thon, Vojtěch and Babar, Judith and Condliffe, Alison M. and Exley, Andrew and Kumararatne, Dinakantha and Screaton, Nick and Jones, Alison and Bondioni, Maria P. and Lougaris, Vassilios and Plebani, Alessandro and Soresina, Annarosa and Sirignano, Cesare and Spadaro, Giuseppe and Galal, Nermeen and GonzalezandGranado, Luis I. and Dettmer, Sabine and Stirling, Robert and Chapel, Helen and Lucas, Mary and Patel, Smita and Farber, ClaireandMichele and Meyts, Isabelle and Banerjee, Arpan K. and Hackett, Scott and Hurst, John R. and Warnatz, Klaus and Gathmann, Benjamin and Baumann, Ulrich},
   article_location = {New York},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s10875-018-0577-9},
   keywords = {Chest CT; CVID; primary antibody deficiency; bronchiectasis; bronchial pathology},
   language = {eng},
   issn = {0271-9142},
   journal = {Journal of Clinical Immunology},
   title = {Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group},
   url = {https://link.springer.com/article/10.1007%2Fs10875-018-0577-9},
   volume = {39},
   year = {2019}
}

TY  - JOUR
ID  - 1549656
AU  - Schutz, Katharina - Alecsandru, Diana - Grimbacher, Bodo - Haddock, Jamanda - Bruining, Annemarie - Driessen, Gertjan - de Vries, Esther - van Hagen, Peter M. - Hartmann, Ieneke - Fraioli, Francesco - Milito, Cinzia - Mitrevski, Milica - Quinti, Isabella - Serra, Goffredo - Kelleher, Peter - Loebinger, Michael - Litzman, Jiří - Postránecká, Věra - Thon, Vojtěch - Babar, Judith - Condliffe, Alison M. - Exley, Andrew - Kumararatne, Dinakantha - Screaton, Nick - Jones, Alison - Bondioni, Maria P. - Lougaris, Vassilios - Plebani, Alessandro - Soresina, Annarosa - Sirignano, Cesare - Spadaro, Giuseppe - Galal, Nermeen - Gonzalez-Granado, Luis I. - Dettmer, Sabine - Stirling, Robert - Chapel, Helen - Lucas, Mary - Patel, Smita - Farber, Claire-Michele - Meyts, Isabelle - Banerjee, Arpan K. - Hackett, Scott - Hurst, John R. - Warnatz, Klaus - Gathmann, Benjamin - Baumann, Ulrich
PY  - 2019
TI  - Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group
JF  - Journal of Clinical Immunology
VL  - 39
IS  - 1
SP  - 45-54
EP  - 45-54
PB  - Springer
SN  - 02719142
KW  - Chest CT
KW  - CVID
KW  - primary antibody deficiency
KW  - bronchiectasis
KW  - bronchial pathology
UR  - https://link.springer.com/article/10.1007%2Fs10875-018-0577-9
L2  - https://link.springer.com/article/10.1007%2Fs10875-018-0577-9
N2  - Studies of chest computed tomography (CT) in patients with primary antibody deficiency syndromes (ADS) suggest a broad range of bronchial pathology. However, there are as yet no multicentre studies to assess the variety of bronchial pathology in this patient group. One of the underlying reasons is the lack of a consensus methodology, a prerequisite to jointly document chest CT findings. We aimed to establish an international platform for the evaluation of bronchial pathology as assessed by chest CT and to describe the range of bronchial pathologies in patients with antibody deficiency. Ffteen immunodeficiency centres from 9 countries evaluated chest CT scans of patients with ADS using a predefined list of potential findings including an extent score for bronchiectasis. Data of 282 patients with ADS were collected. Patients with common variable immunodeficiency disorders (CVID) comprised the largest subgroup (232 patients, 82.3%). Eighty percent of CVID patients had radiological evidence of bronchial pathology including bronchiectasis in 61%, bronchial wall thickening in 44% and mucus plugging in 29%. Bronchiectasis was detected in 44% of CVID patients aged less than 20years. Cough was a better predictor for bronchiectasis than spirometry values. Delay of diagnosis as well as duration of disease correlated positively with presence of bronchiectasis. The use of consensus diagnostic criteria and a pre-defined list of bronchial pathologies allows for comparison of chest CT data in multicentre studies. Our data suggest a high prevalence of bronchial pathology in CVID due to late diagnosis or duration of disease.
ER  -

SCHUTZ, Katharina, Diana ALECSANDRU, Bodo GRIMBACHER, Jamanda HADDOCK, Annemarie BRUINING, Gertjan DRIESSEN, Esther DE VRIES, Peter M. VAN HAGEN, Ieneke HARTMANN, Francesco FRAIOLI, Cinzia MILITO, Milica MITREVSKI, Isabella QUINTI, Goffredo SERRA, Peter KELLEHER, Michael LOEBINGER, Jiří LITZMAN, Věra POSTRÁNECKÁ, Vojtěch THON, Judith BABAR, Alison M. CONDLIFFE, Andrew EXLEY, Dinakantha KUMARARATNE, Nick SCREATON, Alison JONES, Maria P. BONDIONI, Vassilios LOUGARIS, Alessandro PLEBANI, Annarosa SORESINA, Cesare SIRIGNANO, Giuseppe SPADARO, Nermeen GALAL, Luis I. GONZALEZ-GRANADO, Sabine DETTMER, Robert STIRLING, Helen CHAPEL, Mary LUCAS, Smita PATEL, Claire-Michele FARBER, Isabelle MEYTS, Arpan K. BANERJEE, Scott HACKETT, John R. HURST, Klaus WARNATZ, Benjamin GATHMANN a Ulrich BAUMANN. Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. \textit{Journal of Clinical Immunology}. New York: Springer, 2019, roč.~39, č.~1, s.~45-54. ISSN~0271-9142. Dostupné z: https://dx.doi.org/10.1007/s10875-018-0577-9.

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