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@proceedings{1549680,
author = {Blaho, Martin and Kunovský, Lumír and Bojková, Martina and Dítě, Petr},
booktitle = {The 51st Annual Meeting of the European Pancreatic Club},
doi = {http://dx.doi.org/10.1016/j.pan.2019.05.134},
keywords = {Metabolic syndrome; Chronic pancreatitis; Acute pancreatitis},
language = {eng},
title = {The role of metabolic syndrome in patients with chronic pancreatitis after the first attack of acute pancreatitis},
url = {https://www.sciencedirect.com/science/article/pii/S1424390319302376},
year = {2019}
}
TY - CONF
ID - 1549680
AU - Blaho, Martin - Kunovský, Lumír - Bojková, Martina - Dítě, Petr
PY - 2019
TI - The role of metabolic syndrome in patients with chronic pancreatitis after the first attack of acute pancreatitis
KW - Metabolic syndrome
KW - Chronic pancreatitis
KW - Acute pancreatitis
UR - https://www.sciencedirect.com/science/article/pii/S1424390319302376
L2 - https://www.sciencedirect.com/science/article/pii/S1424390319302376
N2 - Background and Objectives: Acute pancreatitis is one of the diseases which carry a potential risk of developing chronic pancreatitis. Metabolic syndrome is another important risk factor in the induction of pancreatic changes. We examined a set of patients after the first attack of acute pancreatitis and in this set we selected a subset of patients with metabolic syndrome. We then evaluated the role of metabolic syndrome in our patients. Materials and Methods: In the set of 231 individuals with chronic pancreatitis a total of 56 patients were initially treated for acute pancreatitis. In 16 patients of this group the diagnosis of metabolic syndrome was found. Results: The mean age of patients with chronic pancreatitis after the first attack of acute pancreatitis was 54 years (42-64), of which there were 28 men (47.5%) and 31 women (52.5%). The most frequent etiological factor was alcohol (52.5%). Biliary etiology was found in 40.7%. In patients with metabolic syndrome, hypertriglyceridaemia was identified in 82.3%, and hyperglycemia in 70.5%. 82.0% of the individuals were obese. Obesity or hypertriglycaeridemia were present in less than 30% and hyperglycemia was positive in 46.4% of a set of 28 patients (group without metabolic syndrome). The mean time interval between the diagnosis of acute pancreatitis and chronic pancreatitis was significantly shorter in the group with metabolic syndrome - 12 (0-14) vs. 20 (16-29) months. Conclusion: 1) Acute pancreatitis is an important factor for the development of chronic pancreatitis. 2) Alcoholic etiology is the most frequent factor, but biliary etiology could also be an important risk factor. 3) Hypertriglycaeridemia and diabetes mellitus type 2 are the most frequent positive components found in patients with chronic pancreatitis and metabolic syndrome. 4) Metabolic syndrome could accelerate the development from acute to chronic pancreatitis.
ER -
BLAHO, Martin, Lumír KUNOVSKÝ, Martina BOJKOVÁ a Petr DÍTĚ. The role of metabolic syndrome in patients with chronic pancreatitis after the first attack of acute pancreatitis. In \textit{The 51st Annual Meeting of the European Pancreatic Club}. 2019. Dostupné z: https://dx.doi.org/10.1016/j.pan.2019.05.134.
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