| MUSIL, Václav, Lukáš HOMOLA, M. VRBA, Adriana BRAUNOVÁ, Tamara KRAVALOVÁ, Miriam MALÁ and Lenka KRBKOVÁ. Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study. Čs. epidemiologie, mikrobiologie, imunologie. Praha: ČSL JEP, 2019, vol. 68, No 2, p. 59-64. ISSN 1210-7913. |
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@article{1551818,
author = {Musil, Václav and Homola, Lukáš and Vrba, M. and Braunová, Adriana and Kravalová, Tamara and Malá, Miriam and Krbková, Lenka},
article_location = {Praha},
article_number = {2},
keywords = {infants; neonates; Clostridium dlifklle; diarrhoea; paediatrics; colonisation},
language = {eng},
issn = {1210-7913},
journal = {Čs. epidemiologie, mikrobiologie, imunologie},
title = {Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study},
url = {https://www.ncbi.nlm.nih.gov/pubmed/31398977},
volume = {68},
year = {2019}
}
TY - JOUR
ID - 1551818
AU - Musil, Václav - Homola, Lukáš - Vrba, M. - Braunová, Adriana - Kravalová, Tamara - Malá, Miriam - Krbková, Lenka
PY - 2019
TI - Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study
JF - Čs. epidemiologie, mikrobiologie, imunologie
VL - 68
IS - 2
SP - 59-64
EP - 59-64
PB - ČSL JEP
SN - 12107913
KW - infants
KW - neonates
KW - Clostridium dlifklle
KW - diarrhoea
KW - paediatrics
KW - colonisation
UR - https://www.ncbi.nlm.nih.gov/pubmed/31398977
L2 - https://www.ncbi.nlm.nih.gov/pubmed/31398977
N2 - Aims: Despite an increasing trend in Clostridium difficile infections (CDI) and high C difficile colonization rate especially among younger children. infants remain quite resistant to the disease. The goals of this study were to distinguish whether there exists a difference in CDI between children with or without diarrhoea, ascertain the prevalence of CDI, and assess CDI severity in children under 3 years with diarrhoea in our institution. Methods: A prospective study was conducted from May 2015 to June 2016. Children 3 years of age or younger were enrolled and into two groups. Every faecal sample was tested using a diagnostic two step screening algorithm including an immunochromatographic test and polymerase chain reaction. Results: The study enrolled 147 children with diarrhoea and 75 control patients. I he prevalence of CDI in children with diarrhoea was 2% (3/147), the prevalence of toxigenic C. difficile in the diarrhoeal group compared to the control group was 11.6 % (17/147) vs. 10.6% (8/75) (p < 0.9999). Conclusions: No significant difference was observed between infants with diarrhoea and the control group. We recommend not examining for C. difficile children not exhibiting specific risk factors.
ER -
MUSIL, Václav, Lukáš HOMOLA, M. VRBA, Adriana BRAUNOVÁ, Tamara KRAVALOVÁ, Miriam MALÁ and Lenka KRBKOVÁ. Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study. \textit{Čs. epidemiologie, mikrobiologie, imunologie}. Praha: ČSL JEP, 2019, vol.~68, No~2, p.~59-64. ISSN~1210-7913.
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