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@article{1565220, author = {Mrózek, Jan and Nečasová, Tereza and Svoboda, Michal and Šimková, Iveta and Jansa, Pavel}, article_location = {Olomouc}, article_number = {4}, doi = {http://dx.doi.org/10.5507/bp.2019.033}, keywords = {pulmonary embolism; prediction score; perfusion defects; reperfusion; risk score; classification}, language = {eng}, issn = {1213-8118}, journal = {Biomedical Papers}, title = {Prediction Score for persisting perfusion defects after pulmonary embolism}, url = {http://dx.doi.org/10.5507/bp.2019.033}, volume = {164}, year = {2020} }
TY - JOUR ID - 1565220 AU - Mrózek, Jan - Nečasová, Tereza - Svoboda, Michal - Šimková, Iveta - Jansa, Pavel PY - 2020 TI - Prediction Score for persisting perfusion defects after pulmonary embolism JF - Biomedical Papers VL - 164 IS - 4 SP - 394-400 EP - 394-400 PB - Univerzita Palackého v Olomouci SN - 12138118 KW - pulmonary embolism KW - prediction score KW - perfusion defects KW - reperfusion KW - risk score KW - classification UR - http://dx.doi.org/10.5507/bp.2019.033 L2 - http://dx.doi.org/10.5507/bp.2019.033 N2 - Long-term persistence of perfusion defect after pulmonary embolism (PE) may lead to the development of chronic thromboembolic pulmonary hypertension. Identification of patients at risk of such a complication using a scoring system would be beneficial in clinical practice. Here, we aimed to derive a score for predicting persistence of perfusion defects after PE.Methods. 83 patients after PE were re-examined 6, 12 and 24 months after the PE episode. Data collected at the time of PE and perfusion status during follow-ups were used for modelling perfusion defects persistence using the Cox proportional hazards model and validated using bootstrap method.Results. A simple scoring system utilizing two variables (hemoglobin levels and age at the time of PE) was developed. Patients with hemoglobin levels over 140 g/L who were older than 65 years were at the highest risk of perfusion defects; in patients with the same hemoglobin levels and age {\&}lt; 65 years, the risk was reduced by 79{\%}, and by 89{\%} in patients with hemoglobin {\&}lt; 140 g/L.Conclusion. The proposed scoring system may be useful in clinical practice for identifying patients with high risk of persisting perfusion defects, flagging them for closer follow up, thus improving the effectiveness of long-term treatment of patients after PE. ER -
MRÓZEK, Jan, Tereza NEČASOVÁ, Michal SVOBODA, Iveta ŠIMKOVÁ a Pavel JANSA. Prediction Score for persisting perfusion defects after pulmonary embolism. \textit{Biomedical Papers}. Olomouc: Univerzita Palackého v Olomouci, 2020, roč.~164, č.~4, s.~394-400. ISSN~1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2019.033.
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