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@proceedings{1569436, author = {Chocholová, Eva and Fialová, Dana and Drozdová, Eva and Skoupý, Radim and Brzobohatá, Kristýna and Zwinsová, Barbora and Vídeňská, Petra and Chochola, Václav}, booktitle = {The Biomania Student Scientific Meeting & EUSynBioS Symposium 2019}, keywords = {ancient DNA; aDNA; pathogen; dental calculus; metagenomics}, language = {eng}, isbn = {978-80-210-9373-7}, title = {Looking at the health of past populations through the lens of human dental calculus}, year = {2019} }
TY - CONF ID - 1569436 AU - Chocholová, Eva - Fialová, Dana - Drozdová, Eva - Skoupý, Radim - Brzobohatá, Kristýna - Zwinsová, Barbora - Vídeňská, Petra - Chochola, Václav PY - 2019 TI - Looking at the health of past populations through the lens of human dental calculus SN - 9788021093737 KW - ancient DNA KW - aDNA KW - pathogen KW - dental calculus KW - metagenomics N2 - Connection of ancient human dental calculus and molecular biology has so far brought up more questions than answers. Dental calculus is a calcified dental plaque and as such, it is mostly composed of bacteria and their products. This opens a door to the research of oral health as well as pathogens found in blood or respiratory system. The presented study shows the potential of molecular research of ancient human dental calculus in connection with health and the problems with authentication of acquired results. Several potential pathogens were detected by sequencing of 16S rDNA in Early Medieval specimens, but an even greater quantity of contaminating organisms was found. How does that change the usefulness of the applied approach? Is there a right way for the interpretation of metagenomic data derived from ancient samples? ER -
CHOCHOLOVÁ, Eva, Dana FIALOVÁ, Eva DROZDOVÁ, Radim SKOUPÝ, Kristýna BRZOBOHATÁ, Barbora ZWINSOVÁ, Petra VÍDEŇSKÁ a Václav CHOCHOLA. Looking at the health of past populations through the lens of human dental calculus. In \textit{The Biomania Student Scientific Meeting \&{} EUSynBioS Symposium 2019}. 2019. ISBN~978-80-210-9373-7.
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