2019
Beat-to-beat variability of pulse wave velocity
SVAČINOVÁ, Jana, Simona HIDEGOVÁ, Helena SIEGLOVÁ, Zuzana KAŠČÁKOVÁ, Martin FABŠÍK et. al.Základní údaje
Originální název
Beat-to-beat variability of pulse wave velocity
Název česky
Variabilita rychlosti pulzové vlny
Autoři
SVAČINOVÁ, Jana (203 Česká republika, garant, domácí), Simona HIDEGOVÁ (703 Slovensko, domácí), Helena SIEGLOVÁ (203 Česká republika, domácí), Zuzana KAŠČÁKOVÁ (703 Slovensko, domácí), Martin FABŠÍK (703 Slovensko, domácí), Juraj JAKUBÍK (703 Slovensko, domácí), Jan NOVÁK (203 Česká republika, domácí), Zuzana NOVÁKOVÁ (203 Česká republika, domácí) a Jana HRUŠKOVÁ (203 Česká republika, domácí)
Vydání
Joint Meeting of the Federation of European Physiological Societies (FEPS) and the Italian Physiological Society (SIF) Bologna (Italy), September 10th – 13th 2019, 2019
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
30105 Physiology
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 5.542
Kód RIV
RIV/00216224:14110/19:00111488
Organizační jednotka
Lékařská fakulta
ISSN
Klíčová slova česky
rychlost pulzové vlny; arteriální compliance
Klíčová slova anglicky
pulse wave velocity; arterial compliance
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 7. 4. 2020 14:39, Mgr. Tereza Miškechová
Anotace
V originále
Pulse wave velocity (PWV) increase is a marker of decreased arterial compliance (C). C decreases with increased blood pressure (BP), due to endothelial dysfunction and structural changes of the arterial wall. Increased mean PWV is observed in diabetics as well as in hypertonics. Mean PWV was analysed in many studies, but beat-to-beat changes of the PWV were less described. Aim of this pilot study is analysis of PWV beat-to-beat variability in dependence of body position. PWV was measured in II. type diabetics (DM: 7m/8f, age 68±10 years, BP 158/90±19/9 mmHg) and healthy controls (Con: 5m/6f, age 23±2 years, BP 117/76±9/5 mmHg). PWV was recorded by method based on multichannel full body bioimpedance. Protocol consisted of 6 min of supine (sup) and 6 min of head up tilt in 45°(hut). PWV of left forearm (PWVlf) and left calf (PWVlc) were measured. Variability was counted as mean power spectra of PWV in frequency bands LF (0.04 – 0.15 Hz) and HF (0.15 – 0.5 Hz). Results: LF-PWVlf, HF-PWVlf and HF-PWVlc in sup were higher in DM than in Con. During hut LF-PWVlc and HF-PWVlc increased in both groups; LF-PWVlf and HF-PWVlf increased only in Con. During hut of DM, PWVlf was lower than PWVlc. Decreased ability of arterial wall to dampen blood pressure changes probably could lead to higher PWV variability. This could be caused by hypertension and changed arterial stiffness (differences between groups), or by blood redistribution during body position change (differences between sup/hut and lf/cl). This pilot study showed, that PWV variability was changed by health condition, body position and measured artery position. Clear understanding of mechanism influencing PWV variability requires further study.
Návaznosti
MUNI/A/1255/2018, interní kód MU |
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MUNI/A/1475/2018, interní kód MU |
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