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@inproceedings{1584738,
author = {Svačinová, Jana and Hidegová, Simona and Sieglová, Helena and Kaščáková, Zuzana and Fabšík, Martin and Jakubík, Juraj and Budinskaya, Ksenia and Novák, Jan and Nováková, Zuzana and Hrušková, Jana},
address = {Brno},
booktitle = {Noninvasive methods in cardiology 2019},
edition = {First edition},
editor = {Cornélissen, G.; Siegelová, J.; Dobšák, P.},
keywords = {pulse wave velocity; arterial compliance},
howpublished = {elektronická verze "online"},
language = {eng},
location = {Brno},
isbn = {978-80-210-9442-0},
pages = {107-111},
publisher = {Masaryk University Press},
title = {A different response of the upper and lower limb beat-to-beat pulse wave velocity to the orthostatic challenge},
url = {https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/noninvasive_methods_in_cardiology_2019.pdf},
year = {2019}
}
TY - JOUR
ID - 1584738
AU - Svačinová, Jana - Hidegová, Simona - Sieglová, Helena - Kaščáková, Zuzana - Fabšík, Martin - Jakubík, Juraj - Budinskaya, Ksenia - Novák, Jan - Nováková, Zuzana - Hrušková, Jana
PY - 2019
TI - A different response of the upper and lower limb beat-to-beat pulse wave velocity to the orthostatic challenge
VL - neuveden
PB - Masaryk University Press
CY - Brno
SN - 9788021094420
KW - pulse wave velocity
KW - arterial compliance
UR - https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/noninvasive_methods_in_cardiology_2019.pdf
L2 - https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/noninvasive_methods_in_cardiology_2019.pdf
N2 - Pulse wave velocity (PWV) increase is a marker of arterial stiffness. PWV increases with increased blood pressure (BP), due to endothelial dysfunction and structural changes of the arterial wall. Increased mean PWV is observed in diabetics as well as in hypertonics. Aim of this pilot study is analysis of arm and leg PWV in dependence of body position in diabetics and young healthy controls. PWV was measured in II. type diabetics (7m/8f, age 68±10 years, BP 158/90±19/9 mmHg) and healthy controls (5m/6f, age 23±2 years, BP 117/76±9/5 mmHg). PWV was recorded by method based on multichannel full body bioimpedance. Protocol consisted of 6 min of supine (sup) and 6 min of head up tilt in 45° (hut). PWV of left arm and left leg were measured. Results: Sup arm PWV was higher in diabetics than in controls regardless on posture. Hut increased leg PWV only in diabetics. Arm/leg PWV ratio vas significantly lower in diabetics during hut compared to controls. Hut/sup PWV ratio was increased in leg of diabetics compared to controls and arm. PWV in diabetics differ between arm and leg and it is significantly influenced by postural changes. Increased supine PWV in diabetics is a marker of increased arterial stiffness, both associated with aging and diabetes. Moreover PWV is directly increased by hypertension. Different response of arm/leg PWV to hut in diabetics is a sign of changed blood redistribution control. Increased hydrostatic pressure in the legs led to a PWV increase. Stronger PWV increase in diabetics suggests changes in endothelial function and autonomic system control over the arterial tonus, both responsible for blood redistribution. We suggest that arm/leg PWV ratio can be suitable parameter for the regular examination of the arterial function development in diabetics.
ER -
SVAČINOVÁ, Jana, Simona HIDEGOVÁ, Helena SIEGLOVÁ, Zuzana KAŠČÁKOVÁ, Martin FABŠÍK, Juraj JAKUBÍK, Ksenia BUDINSKAYA, Jan NOVÁK, Zuzana NOVÁKOVÁ a Jana HRUŠKOVÁ. A different response of the upper and lower limb beat-to-beat pulse wave velocity to the orthostatic challenge. Online. In Cornélissen, G.; Siegelová, J.; Dobšák, P. \textit{Noninvasive methods in cardiology 2019}. First edition. Brno: Masaryk University Press, 2019, s.~107-111. ISBN~978-80-210-9442-0.
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