Cardiac resynchronisation therapy optimisation of
interventricular delay by the systolic dyssynchrony index: A
comparative, randomised, 12-month follow-up study

J 2019

Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study

VONDRAK, Jiri, Dan MAREK, Jan VECERA, Klára BENEŠOVÁ, Jan MATEJKA et. al.

Základní údaje

Originální název

Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study

Autoři

VONDRAK, Jiri (203 Česká republika, garant), Dan MAREK, Jan VECERA, Klára BENEŠOVÁ (203 Česká republika, domácí) a Jan MATEJKA

Vydání

HELLENIC JOURNAL OF CARDIOLOGY, ATHENS, HELLENIC CARDIOLOGICAL SOC, 2019, 1109-9666

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Řecko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.047

Kód RIV

RIV/00216224:14110/19:00111775

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.hjc.2017.11.003

UT WoS

000473281500004

Klíčová slova anglicky

3D echocardiography; cardiac resynchronisation therapy; systolic dyssynchrony index

Štítky

14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 24. 1. 2020 14:44, Mgr. Tereza Miškechová

Anotace

V originále

Background: The aim of our study was to compare the effect of interventricular (VV) delay optimisation in CRT recipients on the basis of systolic dyssynchrony index (SDI) derived from the three-dimensional echocardiography (3DE) versus QRS width assessment on left ventricle volume reduction at the 12-month follow-up. Methods: We included 63 patients with recently implanted CRT in this randomised, open-label trial. Patients were randomised to VV delay optimisation according to QRS complex width measurement in group 1 (n = 31) to obtain the narrowest QRS complex and SDI in group 2 (n = 32) to achieve its lowest possible value. We evaluated left ventricular end-systolic volume (LVESv), left ventricular ejection fraction (LVEF) and SDI by 3DE before CRT implantation and at a 12-month follow-up in all the patients. We also obtained the New York Heart Association functional class, the 6-minute walk test, the quality of life questionnaire and the level of NT-proBNP. Results: The number of volumetric responders was similar in both groups (17 vs. 20, P = 0.786). There were also no significant differences in the reduction of LVESv (-41 +/- 55 mL vs. - 61 +/- 51 mL, P = 0.111), improvement in LVEF (+10.1 +/- 10.6% vs. + 13.0 +/- 9.9%, P = 0.213) or differences in clinical outcomes between both groups at the 12-month follow-up. Conclusion: CRT optimisation of interventricular delay using SDI compared with QRS width assessment did not reveal any significant difference in terms of volumetric and clinical response at the 12-month follow-up. (C) 2017 Hellenic Society of Cardiology. Publishing services by Elsevier B.V.

Citovat

VONDRAK, Jiri, Dan MAREK, Jan VECERA, Klára BENEŠOVÁ a Jan MATEJKA. Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study. HELLENIC JOURNAL OF CARDIOLOGY. ATHENS: HELLENIC CARDIOLOGICAL SOC, 2019, roč. 60, č. 1, s. 16-25. ISSN 1109-9666. Dostupné z: https://dx.doi.org/10.1016/j.hjc.2017.11.003.

@article{1593836,
   author = {Vondrak, Jiri and Marek, Dan and Vecera, Jan and Benešová, Klára and Matejka, Jan},
   article_location = {ATHENS},
   article_number = {1},
   doi = {http://dx.doi.org/10.1016/j.hjc.2017.11.003},
   keywords = {3D echocardiography; cardiac resynchronisation therapy; systolic dyssynchrony index},
   language = {eng},
   issn = {1109-9666},
   journal = {HELLENIC JOURNAL OF CARDIOLOGY},
   title = {Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study},
   url = {http://dx.doi.org/10.1016/j.hjc.2017.11.003},
   volume = {60},
   year = {2019}
}

TY  - JOUR
ID  - 1593836
AU  - Vondrak, Jiri - Marek, Dan - Vecera, Jan - Benešová, Klára - Matejka, Jan
PY  - 2019
TI  - Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study
JF  - HELLENIC JOURNAL OF CARDIOLOGY
VL  - 60
IS  - 1
SP  - 16-25
EP  - 16-25
PB  - HELLENIC CARDIOLOGICAL SOC
SN  - 11099666
KW  - 3D echocardiography
KW  - cardiac resynchronisation therapy
KW  - systolic dyssynchrony index
UR  - http://dx.doi.org/10.1016/j.hjc.2017.11.003
L2  - http://dx.doi.org/10.1016/j.hjc.2017.11.003
N2  - Background: The aim of our study was to compare the effect of interventricular (VV) delay optimisation in CRT recipients on the basis of systolic dyssynchrony index (SDI) derived from the three-dimensional echocardiography (3DE) versus QRS width assessment on left ventricle volume reduction at the 12-month follow-up. Methods: We included 63 patients with recently implanted CRT in this randomised, open-label trial. Patients were randomised to VV delay optimisation according to QRS complex width measurement in group 1 (n = 31) to obtain the narrowest QRS complex and SDI in group 2 (n = 32) to achieve its lowest possible value. We evaluated left ventricular end-systolic volume (LVESv), left ventricular ejection fraction (LVEF) and SDI by 3DE before CRT implantation and at a 12-month follow-up in all the patients. We also obtained the New York Heart Association functional class, the 6-minute walk test, the quality of life questionnaire and the level of NT-proBNP. Results: The number of volumetric responders was similar in both groups (17 vs. 20, P = 0.786). There were also no significant differences in the reduction of LVESv (-41 +/- 55 mL vs. - 61 +/- 51 mL, P = 0.111), improvement in LVEF (+10.1 +/- 10.6% vs. + 13.0 +/- 9.9%, P = 0.213) or differences in clinical outcomes between both groups at the 12-month follow-up. Conclusion: CRT optimisation of interventricular delay using SDI compared with QRS width assessment did not reveal any significant difference in terms of volumetric and clinical response at the 12-month follow-up. (C) 2017 Hellenic Society of Cardiology. Publishing services by Elsevier B.V.
ER  -

VONDRAK, Jiri, Dan MAREK, Jan VECERA, Klára BENEŠOVÁ a Jan MATEJKA. Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study. \textit{HELLENIC JOURNAL OF CARDIOLOGY}. ATHENS: HELLENIC CARDIOLOGICAL SOC, 2019, roč.~60, č.~1, s.~16-25. ISSN~1109-9666. Dostupné z: https://dx.doi.org/10.1016/j.hjc.2017.11.003.

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