Is PET MRI valuable in inflammation or fever of unknown
aetiology?

a 2019

Is PET MRI valuable in inflammation or fever of unknown aetiology?

ROHAN, Tomáš, Tomáš ANDRAŠINA, Alexandra LITAVCOVÁ, Tomáš JŮZA, Jan ZAVADIL et. al.

Základní údaje

Originální název

Is PET MRI valuable in inflammation or fever of unknown aetiology?

Autoři

ROHAN, Tomáš (203 Česká republika, garant, domácí), Tomáš ANDRAŠINA (703 Slovensko, domácí), Alexandra LITAVCOVÁ (703 Slovensko, domácí), Tomáš JŮZA (203 Česká republika, domácí), Jan ZAVADIL (203 Česká republika, domácí), Svatopluk RICHTER (203 Česká republika, domácí) a Vlastimil VÁLEK (203 Česká republika)

Vydání

ECR 2019, 2019

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30224 Radiology, nuclear medicine and medical imaging

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.579

Kód RIV

RIV/00216224:14110/19:00111855

Organizační jednotka

Lékařská fakulta

ISSN

DOI

http://dx.doi.org/10.1186/s13244-019-0713-y

UT WoS

000459898000001

Klíčová slova anglicky

PET/MRI; fever of unknown origin; rheumatic diseases

Štítky

rivok

Změněno: 31. 5. 2022 12:24, RNDr. Pavel Šmerk, Ph.D.

Anotace

V originále

Purpose: To evaluate the benefit of PET/MR imaging in diagnostic process of patients with inflammatory disease of unknown aetiology. Methods and Materials: 51 patients were selected for PET/MR imaging due to inflammation of unknown aetiology, these represent 2.5 % of all PET/MR examinations (total of 2056 examinations; Signa; GE) acquired in tertiary referral hospital since 7/2016. All patients underwent intensive investigation lasting at least 20 days (screening x-rays; abdominal ultrasound, dedicated CT or MRI focused in clinical suspect). Clinical (fever; artralgia; weight loss; night sweating) and laboratory (CRP, leukocytes) were monitored and correlated with PET/MR findings. Based on suspected aetiology patients were divided into 3 groups - fewer of unknown origin (26), unknown infection (13) and rheumatic disease (12). Patients were followed up until the aetiology was diagnosed or symptoms faded away. Results: In 26 (51%) patients diagnosis was proved, in 22 (43%) patients symptoms disappeared, in 3 patients symptoms persisted without explanation. PET/MR strongly supported or changed the diagnosis in 42% of cases (70% in subgroup of rheumatoid infections). As most important marker of conclusive PET/MR was shown artralgia and elevated level of CRP at the time of examination, which were present in 54% of diagnosed cases. PET/MR proved diagnosis of rheumatoid disease in 18 patients (50% without any clinical suspicion), overall sensitivity was up to 89% and specificity 100%, negative predictive value was 85%. Conclusion: PET-MRI is a useful tool in the evaluation of inflammatory disease of unknown aetiology especially in patients with suspected rheumatoid disease.

Návaznosti

MUNI/A/1574/2018, interní kód MU

Název: Onkologické radiologické intervence a jejich přínos v rámci komplexní onkologické léčby, srovnání s celorepublikovými výsledky onkologické léčby vybraných diagnóz II

Investor: Masarykova univerzita, Onkologické radiologické intervence a jejich přínos v rámci komplexní onkologické léčby, srovnání s celorepublikovými výsledky onkologické léčby vybraných diagnóz II, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

ROHAN, Tomáš, Tomáš ANDRAŠINA, Alexandra LITAVCOVÁ, Tomáš JŮZA, Jan ZAVADIL, Svatopluk RICHTER a Vlastimil VÁLEK. Is PET MRI valuable in inflammation or fever of unknown aetiology? In ECR 2019. 2019. ISSN 1869-4101. Dostupné z: https://dx.doi.org/10.1186/s13244-019-0713-y.

@proceedings{1595738,
   author = {Rohan, Tomáš and Andrašina, Tomáš and Litavcová, Alexandra and Jůza, Tomáš and Zavadil, Jan and Richter, Svatopluk and Válek, Vlastimil},
   booktitle = {ECR 2019},
   doi = {http://dx.doi.org/10.1186/s13244-019-0713-y},
   keywords = {PET/MRI; fever of unknown origin; rheumatic diseases},
   language = {eng},
   title = {Is PET MRI valuable in inflammation or fever of unknown aetiology?},
   url = {https://insightsimaging.springeropen.com/track/pdf/10.1186/s13244-019-0713-y},
   year = {2019}
}

TY  - CONF
ID  - 1595738
AU  - Rohan, Tomáš - Andrašina, Tomáš - Litavcová, Alexandra - Jůza, Tomáš - Zavadil, Jan - Richter, Svatopluk - Válek, Vlastimil
PY  - 2019
TI  - Is PET MRI valuable in inflammation or fever of unknown aetiology?
KW  - PET/MRI
KW  - fever of unknown origin
KW  - rheumatic diseases
UR  - https://insightsimaging.springeropen.com/track/pdf/10.1186/s13244-019-0713-y
L2  - https://insightsimaging.springeropen.com/track/pdf/10.1186/s13244-019-0713-y
N2  - Purpose: To evaluate the benefit of PET/MR imaging in diagnostic process of patients with inflammatory disease of unknown aetiology. Methods and Materials: 51 patients were selected for PET/MR imaging due to inflammation of unknown aetiology, these represent 2.5 % of all PET/MR examinations (total of 2056 examinations; Signa; GE) acquired in tertiary referral hospital since 7/2016. All patients underwent intensive investigation lasting at least 20 days (screening x-rays; abdominal ultrasound, dedicated CT or MRI focused in clinical suspect). Clinical (fever; artralgia; weight loss; night sweating) and laboratory (CRP, leukocytes) were monitored and correlated with PET/MR findings. Based on suspected aetiology patients were divided into 3 groups - fewer of unknown origin (26), unknown infection (13) and rheumatic disease (12). Patients were followed up until the aetiology was diagnosed or symptoms faded away. Results: In 26 (51%) patients diagnosis was proved, in 22 (43%) patients symptoms disappeared, in 3 patients symptoms persisted without explanation. PET/MR strongly supported or changed the diagnosis in 42% of cases (70% in subgroup of rheumatoid infections). As most important marker of conclusive PET/MR was shown artralgia and elevated level of CRP at the time of examination, which were present in 54% of diagnosed cases. PET/MR proved diagnosis of rheumatoid disease in 18 patients (50% without any clinical suspicion), overall sensitivity was up to 89% and specificity 100%, negative predictive value was 85%. Conclusion: PET-MRI is a useful tool in the evaluation of inflammatory disease of unknown aetiology especially in patients with suspected rheumatoid disease.
ER  -

ROHAN, Tomáš, Tomáš ANDRAŠINA, Alexandra LITAVCOVÁ, Tomáš JŮZA, Jan ZAVADIL, Svatopluk RICHTER a Vlastimil VÁLEK. Is PET MRI valuable in inflammation or fever of unknown aetiology? In \textit{ECR 2019}. 2019. ISSN~1869-4101. Dostupné z: https://dx.doi.org/10.1186/s13244-019-0713-y.

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