Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma

ŠRÁMKOVÁ, Petra, Anna ZAHORANOVÁ, Jakub KELAR, Zlata KELAR TUČEKOVÁ, Monika STUPAVSKÁ, Jana JURMANOVÁ, Dušan KOVÁČIK and Mirko ČERNÁK. Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma. In 1st Plasma for Nanotechnology and Bioapplications Workshop. 2019. ISBN 978-80-210-9487-1.

Basic information

• Original name: Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma
• Name in Czech: Hydrofilné povrchy na báze poly(2-oxazolínu) pripravené pomocou nerovnovážnej "studenej" plazmy pri atmosférickom tlaku
• Authors: ŠRÁMKOVÁ, Petra (703 Slovakia, guarantor, belonging to the institution), Anna ZAHORANOVÁ (703 Slovakia), Jakub KELAR (203 Czech Republic, belonging to the institution), Zlata KELAR TUČEKOVÁ (703 Slovakia, belonging to the institution), Monika STUPAVSKÁ (703 Slovakia, belonging to the institution), Jana JURMANOVÁ (203 Czech Republic, belonging to the institution), Dušan KOVÁČIK (703 Slovakia, belonging to the institution) and Mirko ČERNÁK (703 Slovakia, belonging to the institution).
• Edition: 1st Plasma for Nanotechnology and Bioapplications Workshop, 2019.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10305 Fluids and plasma physics
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• WWW: Book of Abstracts, 1st Plasma for Nanotechnology and Bioapplications Workshop
• RIV identification code: RIV/00216224:14310/19:00112052
• Organization unit: Faculty of Science
• ISBN: 978-80-210-9487-1
• Keywords in English: poly(2-oxazoline); cold atmospheric pressure plasma; coplanar discharge; biological active coatings; cells adhesion
• Tags: 2-oxazoline, DCSBD, plasma activation, PTFE, rivok
• Tags: International impact, Reviewed

Abstract

Due to biological inertness and excellent stability, polytetrafluoroethylene (PTFE) is extensively used for the manufacturing of vascular grafts and various implants. However, its highly hydrophobic nature is disadvantageous for specific biomedical applications requiring the control of the proteins or cell adhesion. Hydrophobicity can be decreased by surface modification using the various biocompatible polymers. In our contribution, we proposed the new method for PTFE surface coating by synthetic hydrophilic polymers, so-called poly(2-oxazolines) (POx). Immobilization of the POx layer was performed employing non-equilibrium “cold” atmospheric pressure plasma generated by the diffuse coplanar surface barrier discharge (DCSBD). Our main objective was to achieve the stable and biologically active cross-linked POx layer immobilized on the PTFE surface. This study provides a new approach for the preparation of POx coatings, which is faster, easier, and more environmentally friendly in comparison to traditional grafting methods or plasma-assisted polymerization.

Links

• EF16_027/0008360, research and development project: Name: Postdoc@MUNI