| EINSPIELER, Christa, Arend F. BOS, Magdalena KRIEBER-TOMANT, Elsa ALVARADO, Vanessa M. BARBOSA, Natascia BERTONCELLI, Marlette BURGER, Olena CHORNA, Sabrina DEL SECCO, Raye-Ann DEREGNIER, Britta HÜNING, Jooyeon KO, Laura LUCACCIONI, Tomoki MAEDA, Viviana MARCHI, Erika MARTÍN, Catherine MORGAN, Akmer MUTLU, Alice NOGOLOVÁ, Jasmin PANSY, Colleen PEYTON, Florian B. POKORNY, Lucia R. PRINSLOO, Eileen RICCI, Lokesh SAINI, Anna SCHEUCHENEGGER, Cinthia R. D. SILVA, Marina SOLOVEICHICK, Alicia J. SPITTLE, Moreno TOLDO, Fabiana UTSCH, Jeanetta VAN ZYL, Carlos VIÑALS, Wang JUN, Yang HONG, Bilge N. YARDIMCI-LOKMANOĞLU, Giovanni CIONI, Fabrizio FERRARI, Andrea GUZZETTA a Peter B. MARSCHIK. Cerebral Palsy: Early Markers of Clinical Phenotype and Functional Outcome. Journal of Clinical Medicine. Basel: MDPI, 2019, roč. 8, č. 10, s. 1-27. ISSN 2077-0383. Dostupné z: https://dx.doi.org/10.3390/jcm8101616. |
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@article{1599457,
author = {Einspieler, Christa and Bos, Arend F. and KrieberandTomant, Magdalena and Alvarado, Elsa and Barbosa, Vanessa M. and Bertoncelli, Natascia and Burger, Marlette and Chorna, Olena and Del Secco, Sabrina and DeRegnier, RayeandAnn and Hüning, Britta and Ko, Jooyeon and Lucaccioni, Laura and Maeda, Tomoki and Marchi, Viviana and Martín, Erika and Morgan, Catherine and Mutlu, Akmer and Nogolová, Alice and Pansy, Jasmin and Peyton, Colleen and Pokorny, Florian B. and Prinsloo, Lucia R. and Ricci, Eileen and Saini, Lokesh and Scheuchenegger, Anna and Silva, Cinthia R. D. and Soloveichick, Marina and Spittle, Alicia J. and Toldo, Moreno and Utsch, Fabiana and van Zyl, Jeanetta and Viñals, Carlos and Jun, Wang and Hong, Yang and YardımcıandLokmanoğlu, Bilge N. and Cioni, Giovanni and Ferrari, Fabrizio and Guzzetta, Andrea and Marschik, Peter B.},
article_location = {Basel},
article_number = {10},
doi = {http://dx.doi.org/10.3390/jcm8101616},
keywords = {cerebral palsy; dyskinesi; fidgety movements; general movements; GMFCS; hemiplegia; hypotonia; identification; motor optimality score; segmental movements},
language = {eng},
issn = {2077-0383},
journal = {Journal of Clinical Medicine},
title = {Cerebral Palsy: Early Markers of Clinical Phenotype and Functional Outcome},
url = {http://dx.doi.org/10.3390/jcm8101616},
volume = {8},
year = {2019}
}
TY - JOUR
ID - 1599457
AU - Einspieler, Christa - Bos, Arend F. - Krieber-Tomant, Magdalena - Alvarado, Elsa - Barbosa, Vanessa M. - Bertoncelli, Natascia - Burger, Marlette - Chorna, Olena - Del Secco, Sabrina - DeRegnier, Raye-Ann - Hüning, Britta - Ko, Jooyeon - Lucaccioni, Laura - Maeda, Tomoki - Marchi, Viviana - Martín, Erika - Morgan, Catherine - Mutlu, Akmer - Nogolová, Alice - Pansy, Jasmin - Peyton, Colleen - Pokorny, Florian B. - Prinsloo, Lucia R. - Ricci, Eileen - Saini, Lokesh - Scheuchenegger, Anna - Silva, Cinthia R. D. - Soloveichick, Marina - Spittle, Alicia J. - Toldo, Moreno - Utsch, Fabiana - van Zyl, Jeanetta - Viñals, Carlos - Jun, Wang - Hong, Yang - Yardımcı-Lokmanoğlu, Bilge N. - Cioni, Giovanni - Ferrari, Fabrizio - Guzzetta, Andrea - Marschik, Peter B.
PY - 2019
TI - Cerebral Palsy: Early Markers of Clinical Phenotype and Functional Outcome
JF - Journal of Clinical Medicine
VL - 8
IS - 10
SP - 1-27
EP - 1-27
PB - MDPI
SN - 20770383
KW - cerebral palsy
KW - dyskinesi
KW - fidgety movements
KW - general movements
KW - GMFCS
KW - hemiplegia
KW - hypotonia
KW - identification
KW - motor optimality score
KW - segmental movements
UR - http://dx.doi.org/10.3390/jcm8101616
L2 - http://dx.doi.org/10.3390/jcm8101616
N2 - The Prechtl General Movement Assessment (GMA) has become a cornerstone assessment in early identification of cerebral palsy (CP), particularly during the fidgety movement period at 3-5 months of age. Additionally, assessment of motor repertoire, such as antigravity movements and postural patterns, which form the Motor Optimality Score (MOS), may provide insight into an infant's later motor function. This study aimed to identify early specific markers for ambulation, gross motor function (using the Gross Motor Function Classification System, GMFCS), topography (unilateral, bilateral), and type (spastic, dyskinetic, ataxic, and hypotonic) of CP in a large worldwide cohort of 468 infants. We found that 95% of children with CP did not have fidgety movements, with 100% having non-optimal MOS. GMFCS level was strongly correlated to MOS. An MOS > 14 was most likely associated with GMFCS outcomes I or II, whereas GMFCS outcomes IV or V were hardly ever associated with an MOS > 8. A number of different movement patterns were associated with more severe functional impairment (GMFCS III-V), including atypical arching and persistent cramped-synchronized movements. Asymmetrical segmental movements were strongly associated with unilateral CP. Circular arm movements were associated with dyskinetic CP. This study demonstrated that use of the MOS contributes to understanding later CP prognosis, including early markers for type and severity.
ER -
EINSPIELER, Christa, Arend F. BOS, Magdalena KRIEBER-TOMANT, Elsa ALVARADO, Vanessa M. BARBOSA, Natascia BERTONCELLI, Marlette BURGER, Olena CHORNA, Sabrina DEL SECCO, Raye-Ann DEREGNIER, Britta HÜNING, Jooyeon KO, Laura LUCACCIONI, Tomoki MAEDA, Viviana MARCHI, Erika MARTÍN, Catherine MORGAN, Akmer MUTLU, Alice NOGOLOVÁ, Jasmin PANSY, Colleen PEYTON, Florian B. POKORNY, Lucia R. PRINSLOO, Eileen RICCI, Lokesh SAINI, Anna SCHEUCHENEGGER, Cinthia R. D. SILVA, Marina SOLOVEICHICK, Alicia J. SPITTLE, Moreno TOLDO, Fabiana UTSCH, Jeanetta VAN ZYL, Carlos VIÑALS, Wang JUN, Yang HONG, Bilge N. YARDIMCI-LOKMANOĞLU, Giovanni CIONI, Fabrizio FERRARI, Andrea GUZZETTA a Peter B. MARSCHIK. Cerebral Palsy: Early Markers of Clinical Phenotype and Functional Outcome. \textit{Journal of Clinical Medicine}. Basel: MDPI, 2019, roč.~8, č.~10, s.~1-27. ISSN~2077-0383. Dostupné z: https://dx.doi.org/10.3390/jcm8101616.
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