Prevalence and predictors of coronary artery disease in
patients undergoing carotid artery stenting

J 2019

Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting

SULŽENKO, Jakub, Piotr PALUSZEK, Roman MACHNÍK, Petr WIDIMSKÝ, Jiří JARKOVSKÝ et. al.

Základní údaje

Originální název

Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting

Autoři

SULŽENKO, Jakub (203 Česká republika, garant), Piotr PALUSZEK (616 Polsko), Roman MACHNÍK (616 Polsko), Petr WIDIMSKÝ (203 Česká republika), Jiří JARKOVSKÝ (203 Česká republika, domácí) a Piotr PIENIAZEK (616 Polsko)

Vydání

Coronary Artery Disease, Philadelphia, Lippincott, 2019, 0954-6928

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.335

Kód RIV

RIV/00216224:14110/19:00112685

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1097/MCA.0000000000000695

UT WoS

000465996500007

Klíčová slova anglicky

atherosclerosis; cardiovascular risk; peripheral artery disease

Štítky

14119612, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 6. 2020 07:51, Mgr. Tereza Miškechová

Anotace

V originále

Introduction A relationship between carotid stenosis and coronary arterial disease (CAD) is widely accepted; however, data on the exact prevalence of coronary disease in patients with severe carotid stenosis are lacking. Information on the prevalence and predictors of CAD among these patients could impact diagnostic and treatment approaches. Aim The primary aim of this study was to determine the prevalence of significant CAD among patients referred for carotid artery revascularization. The secondary objectives included characterizing the association between the level of advancement of carotid stenosis and the presence of CAD, and between atherosclerotic risk factors and the presence of CAD in patients with carotid stenosis, and also to determine whether there was a difference in the prevalence of CAD between patients with symptomatic versus asymptomatic carotid stenosis. Patients and methods We included 200 patients with severe carotid stenosis, of whom 77 (38.5%) had symptomatic stenosis. All patients underwent coronary angiography no more than 6 months before the scheduled carotid revascularization. Of the 200 total of patients, 192 underwent carotid stenting, six underwent carotid endarterectomy, and two were treated conservatively. CAD was defined as stenosis of at least 50% on recent coronary angiography or a history of previous percutaneous coronary intervention and/or coronary aortic bypass graft; the prevalence was 77.5% among our patients. There was no statistically significant difference in the prevalence of CAD between patients with unilateral versus bilateral carotid stenosis or contralateral carotid occlusion. The difference in the severity of coronary disease, which was given by the SYNTAX score, was not significant between these groups. Factors associated with the presence of CAD were male sex, a history of smoking, and global or regional wall motion disorder on echocardiography. We did not find any significant difference in the prevalence of CAD between patients with symptomatic versus asymptomatic carotid stenosis. Conclusion We observed a very high prevalence of concomitant CAD in patients with severe carotid stenosis. The results of our study suggest that routine preprocedural screening for CAD in patients with carotid artery stenosis could identify a large proportion of patients with silent CAD; whether treatment for CAD before carotid revascularization can prevent periprocedural myocardial infarction should be addressed in a randomized-controlled trial.

Citovat

SULŽENKO, Jakub, Piotr PALUSZEK, Roman MACHNÍK, Petr WIDIMSKÝ, Jiří JARKOVSKÝ a Piotr PIENIAZEK. Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting. Coronary Artery Disease. Philadelphia: Lippincott, 2019, roč. 30, č. 3, s. 204-210. ISSN 0954-6928. Dostupné z: https://dx.doi.org/10.1097/MCA.0000000000000695.

@article{1608281,
   author = {Sulženko, Jakub and Paluszek, Piotr and Machník, Roman and Widimský, Petr and Jarkovský, Jiří and Pieniazek, Piotr},
   article_location = {Philadelphia},
   article_number = {3},
   doi = {http://dx.doi.org/10.1097/MCA.0000000000000695},
   keywords = {atherosclerosis; cardiovascular risk; peripheral artery disease},
   language = {eng},
   issn = {0954-6928},
   journal = {Coronary Artery Disease},
   title = {Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting},
   url = {https://journals.lww.com/coronary-artery/Abstract/2019/05000/Prevalence_and_predictors_of_coronary_artery.7.aspx},
   volume = {30},
   year = {2019}
}

TY  - JOUR
ID  - 1608281
AU  - Sulženko, Jakub - Paluszek, Piotr - Machník, Roman - Widimský, Petr - Jarkovský, Jiří - Pieniazek, Piotr
PY  - 2019
TI  - Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting
JF  - Coronary Artery Disease
VL  - 30
IS  - 3
SP  - 204-210
EP  - 204-210
PB  - Lippincott
SN  - 09546928
KW  - atherosclerosis
KW  - cardiovascular risk
KW  - peripheral artery disease
UR  - https://journals.lww.com/coronary-artery/Abstract/2019/05000/Prevalence_and_predictors_of_coronary_artery.7.aspx
L2  - https://journals.lww.com/coronary-artery/Abstract/2019/05000/Prevalence_and_predictors_of_coronary_artery.7.aspx
N2  - Introduction A relationship between carotid stenosis and coronary arterial disease (CAD) is widely accepted; however, data on the exact prevalence of coronary disease in patients with severe carotid stenosis are lacking. Information on the prevalence and predictors of CAD among these patients could impact diagnostic and treatment approaches. Aim The primary aim of this study was to determine the prevalence of significant CAD among patients referred for carotid artery revascularization. The secondary objectives included characterizing the association between the level of advancement of carotid stenosis and the presence of CAD, and between atherosclerotic risk factors and the presence of CAD in patients with carotid stenosis, and also to determine whether there was a difference in the prevalence of CAD between patients with symptomatic versus asymptomatic carotid stenosis. Patients and methods We included 200 patients with severe carotid stenosis, of whom 77 (38.5%) had symptomatic stenosis. All patients underwent coronary angiography no more than 6 months before the scheduled carotid revascularization. Of the 200 total of patients, 192 underwent carotid stenting, six underwent carotid endarterectomy, and two were treated conservatively. CAD was defined as stenosis of at least 50% on recent coronary angiography or a history of previous percutaneous coronary intervention and/or coronary aortic bypass graft; the prevalence was 77.5% among our patients. There was no statistically significant difference in the prevalence of CAD between patients with unilateral versus bilateral carotid stenosis or contralateral carotid occlusion. The difference in the severity of coronary disease, which was given by the SYNTAX score, was not significant between these groups. Factors associated with the presence of CAD were male sex, a history of smoking, and global or regional wall motion disorder on echocardiography. We did not find any significant difference in the prevalence of CAD between patients with symptomatic versus asymptomatic carotid stenosis. Conclusion We observed a very high prevalence of concomitant CAD in patients with severe carotid stenosis. The results of our study suggest that routine preprocedural screening for CAD in patients with carotid artery stenosis could identify a large proportion of patients with silent CAD; whether treatment for CAD before carotid revascularization can prevent periprocedural myocardial infarction should be addressed in a randomized-controlled trial.
ER  -

SULŽENKO, Jakub, Piotr PALUSZEK, Roman MACHNÍK, Petr WIDIMSKÝ, Jiří JARKOVSKÝ a Piotr PIENIAZEK. Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting. \textit{Coronary Artery Disease}. Philadelphia: Lippincott, 2019, roč.~30, č.~3, s.~204-210. ISSN~0954-6928. Dostupné z: https://dx.doi.org/10.1097/MCA.0000000000000695.

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