2019
Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting
SULŽENKO, Jakub, Piotr PALUSZEK, Roman MACHNÍK, Petr WIDIMSKÝ, Jiří JARKOVSKÝ et. al.Základní údaje
Originální název
Prevalence and predictors of coronary artery disease in patients undergoing carotid artery stenting
Autoři
SULŽENKO, Jakub (203 Česká republika, garant), Piotr PALUSZEK (616 Polsko), Roman MACHNÍK (616 Polsko), Petr WIDIMSKÝ (203 Česká republika), Jiří JARKOVSKÝ (203 Česká republika, domácí) a Piotr PIENIAZEK (616 Polsko)
Vydání
Coronary Artery Disease, Philadelphia, Lippincott, 2019, 0954-6928
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 1.335
Kód RIV
RIV/00216224:14110/19:00112685
Organizační jednotka
Lékařská fakulta
UT WoS
000465996500007
Klíčová slova anglicky
atherosclerosis; cardiovascular risk; peripheral artery disease
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 22. 6. 2020 07:51, Mgr. Tereza Miškechová
Anotace
V originále
Introduction A relationship between carotid stenosis and coronary arterial disease (CAD) is widely accepted; however, data on the exact prevalence of coronary disease in patients with severe carotid stenosis are lacking. Information on the prevalence and predictors of CAD among these patients could impact diagnostic and treatment approaches. Aim The primary aim of this study was to determine the prevalence of significant CAD among patients referred for carotid artery revascularization. The secondary objectives included characterizing the association between the level of advancement of carotid stenosis and the presence of CAD, and between atherosclerotic risk factors and the presence of CAD in patients with carotid stenosis, and also to determine whether there was a difference in the prevalence of CAD between patients with symptomatic versus asymptomatic carotid stenosis. Patients and methods We included 200 patients with severe carotid stenosis, of whom 77 (38.5%) had symptomatic stenosis. All patients underwent coronary angiography no more than 6 months before the scheduled carotid revascularization. Of the 200 total of patients, 192 underwent carotid stenting, six underwent carotid endarterectomy, and two were treated conservatively. CAD was defined as stenosis of at least 50% on recent coronary angiography or a history of previous percutaneous coronary intervention and/or coronary aortic bypass graft; the prevalence was 77.5% among our patients. There was no statistically significant difference in the prevalence of CAD between patients with unilateral versus bilateral carotid stenosis or contralateral carotid occlusion. The difference in the severity of coronary disease, which was given by the SYNTAX score, was not significant between these groups. Factors associated with the presence of CAD were male sex, a history of smoking, and global or regional wall motion disorder on echocardiography. We did not find any significant difference in the prevalence of CAD between patients with symptomatic versus asymptomatic carotid stenosis. Conclusion We observed a very high prevalence of concomitant CAD in patients with severe carotid stenosis. The results of our study suggest that routine preprocedural screening for CAD in patients with carotid artery stenosis could identify a large proportion of patients with silent CAD; whether treatment for CAD before carotid revascularization can prevent periprocedural myocardial infarction should be addressed in a randomized-controlled trial.