2019
Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury
GRIVA, Martin, Jiri STASTNY, Petr KOPRIVA, Martin SLABAK, Zdenek COUFAL et. al.Základní údaje
Originální název
Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury
Autoři
GRIVA, Martin (203 Česká republika, garant), Jiri STASTNY (203 Česká republika), Petr KOPRIVA (203 Česká republika), Martin SLABAK (203 Česká republika), Zdenek COUFAL (203 Česká republika), Jiří JARKOVSKÝ (203 Česká republika, domácí), Michal SVOBODA (203 Česká republika, domácí), Tomas SALEK (203 Česká republika), Lucie SUKUPOVA (203 Česká republika) a Milos TABORSKY (203 Česká republika)
Vydání
Biomedical Papers, Olomouc, Palacky University, 2019, 1213-8118
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 1.000
Kód RIV
RIV/00216224:14110/19:00112748
Organizační jednotka
Lékařská fakulta
UT WoS
000506054400006
Klíčová slova anglicky
coronary angiography; percutaneous coronary intervention; high-sensitivity troponin; periprocedural myocardial injury
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 11. 5. 2020 13:25, Mgr. Tereza Miškechová
Anotace
V originále
Background. While there have been a number of studies reporting the incidence and implications of elevated troponin levels after percutaneous coronary intervention (PCI), the body of information about the incidence, associations, and implications of elevated troponin levels following coronary angiography (CAG) is limited. Materials and Methods. A total of 220 consecutive patients with stable coronary artery disease or intermediate or low-risk acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) were included in our study. High-sensitivity cardiac troponin I (hs-cTnI) levels were measured before and after coronary angiography (CAG) in patients with or without PCI and correlated with a number of clinical variables. Results. Hs-cTnl elevations above the 99th percentile upper reference limit (URL), or above 20% of the initially positive, yet already declining values, were found in 60 (37.2%) patients after CAG and in 45 (76.2%) patients undergoing PCI. Significant correlations of hs-cTnI elevation were found with the following variables: volume of contrast, fluoroscopy time, dose-area product, amount of contrast agent injected directly into the coronary arteries, total time of balloon dilation and the number and total length of implanted stents (P<0.001 for all). Conclusion. While an asymptomatic elevation of hs-cTnl is a common finding after PCI, it does occur, quite surprisingly, also after CAG. Despite contradictory views regarding the clinical relevance of asymptomatic post-procedural elevated hs-cTnl levels, it is generally believed that a mild elevation is not associated with an increased risk. Still, it may pose a diagnostic quandary following a successful interventional procedure and even more so after an uncomplicated CAG.