J 2019

Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury

GRIVA, Martin, Jiri STASTNY, Petr KOPRIVA, Martin SLABAK, Zdenek COUFAL et. al.

Základní údaje

Originální název

Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury

Autoři

GRIVA, Martin (203 Česká republika, garant), Jiri STASTNY (203 Česká republika), Petr KOPRIVA (203 Česká republika), Martin SLABAK (203 Česká republika), Zdenek COUFAL (203 Česká republika), Jiří JARKOVSKÝ (203 Česká republika, domácí), Michal SVOBODA (203 Česká republika, domácí), Tomas SALEK (203 Česká republika), Lucie SUKUPOVA (203 Česká republika) a Milos TABORSKY (203 Česká republika)

Vydání

Biomedical Papers, Olomouc, Palacky University, 2019, 1213-8118

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.000

Kód RIV

RIV/00216224:14110/19:00112748

Organizační jednotka

Lékařská fakulta

UT WoS

000506054400006

Klíčová slova anglicky

coronary angiography; percutaneous coronary intervention; high-sensitivity troponin; periprocedural myocardial injury

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 11. 5. 2020 13:25, Mgr. Tereza Miškechová

Anotace

V originále

Background. While there have been a number of studies reporting the incidence and implications of elevated troponin levels after percutaneous coronary intervention (PCI), the body of information about the incidence, associations, and implications of elevated troponin levels following coronary angiography (CAG) is limited. Materials and Methods. A total of 220 consecutive patients with stable coronary artery disease or intermediate or low-risk acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) were included in our study. High-sensitivity cardiac troponin I (hs-cTnI) levels were measured before and after coronary angiography (CAG) in patients with or without PCI and correlated with a number of clinical variables. Results. Hs-cTnl elevations above the 99th percentile upper reference limit (URL), or above 20% of the initially positive, yet already declining values, were found in 60 (37.2%) patients after CAG and in 45 (76.2%) patients undergoing PCI. Significant correlations of hs-cTnI elevation were found with the following variables: volume of contrast, fluoroscopy time, dose-area product, amount of contrast agent injected directly into the coronary arteries, total time of balloon dilation and the number and total length of implanted stents (P<0.001 for all). Conclusion. While an asymptomatic elevation of hs-cTnl is a common finding after PCI, it does occur, quite surprisingly, also after CAG. Despite contradictory views regarding the clinical relevance of asymptomatic post-procedural elevated hs-cTnl levels, it is generally believed that a mild elevation is not associated with an increased risk. Still, it may pose a diagnostic quandary following a successful interventional procedure and even more so after an uncomplicated CAG.