Psoas density is associated with postoperative mortality after
resection for colon cancer

a 2020

Psoas density is associated with postoperative mortality after resection for colon cancer

PEKAŘ, Matej, Anna PEKAŘOVÁ, Lucia HAVRLENTOVÁ, Zdeněk JANDA, Miloslav MAZUR et. al.

Základní údaje

Originální název

Psoas density is associated with postoperative mortality after resection for colon cancer

Autoři

PEKAŘ, Matej, Anna PEKAŘOVÁ, Lucia HAVRLENTOVÁ, Zdeněk JANDA, Miloslav MAZUR a Zuzana NOVÁKOVÁ

Vydání

PragueONCO 2020, 2020

Další údaje

Typ výsledku

Konferenční abstrakt

Utajení

není předmětem státního či obchodního tajemství

ISBN

978-80-87339-61-9

Klíčová slova anglicky

colon cancer, sarcopenia, 30-day mortality

Změněno: 29. 1. 2020 17:47, MUDr. Matej Pekař, Ph.D., MBA

Anotace

V originále

AIM: to evaluate computed tomography scans of total muscle area and radiation attenutation in patients before resection for colon cancer as a predictive factor for postoperative mortality. METHOD: In this retrospective study we examined 65 patients, who underwent a surgical curative resection for malignant colon carcinoma (mean age 68.5±10.8 years, BMI 28.51±5.9 kg/m2, 30-day mortality was 7.7%). Preoperative computed tomography scans were performed in every patient. We compared postoperative mortality in assotiation with an average psoas density (PD), total psoas muscle area (TPA) and total abdominal muscle area (TMA) at the third lumbar vertebra level. We used Mann-Whitney for statistical testing with 80 % power and the significance level of 0.05. RESULTS: We found statistically significant correlation in the psoas muscle radiation attenuation associated with postoperative 30-day mortality: survival vs. non-survival: PD: 42.7 vs. 34.0 HU, p=0.026. There were non-significant differences in TPA: 8.44 vs. 7.22 cm2/m2, p=0.39 and TMA: 72.66 vs. 71.26 cm2/m2, p=0.71. CONCLUSION: The results show the detectable changes in computed tomography scans associated with 30-day mortality in patients after colon cancer surgery. The significant difference is perceived only between the muscle radiation density and not the muscle area. This is caused by muscle´s fat infiltration, that does not affect the volume of muscle, however its function is impaired. Supported by: This publication was written with the support of the Specific University Research no. MUNI/A/1307/2019 provided by MŠMT.

Návaznosti

MUNI/A/1307/2019, interní kód MU

Název: Kardiovaskulární systém od A do Z (Akronym: KAVASAZ)

Investor: Masarykova univerzita, Kardiovaskulární systém od A do Z, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

PEKAŘ, Matej, Anna PEKAŘOVÁ, Lucia HAVRLENTOVÁ, Zdeněk JANDA, Miloslav MAZUR a Zuzana NOVÁKOVÁ. Psoas density is associated with postoperative mortality after resection for colon cancer. In PragueONCO 2020. 2020. ISBN 978-80-87339-61-9.

@proceedings{1611997,
   author = {Pekař, Matej and Pekařová, Anna and Havrlentová, Lucia and Janda, Zdeněk and Mazur, Miloslav and Nováková, Zuzana},
   booktitle = {PragueONCO 2020},
   keywords = {colon cancer, sarcopenia, 30-day mortality},
   isbn = {978-80-87339-61-9},
   title = {Psoas density is associated with postoperative mortality after resection for colon cancer},
   year = {2020}
}

TY  - CONF
ID  - 1611997
AU  - Pekař, Matej - Pekařová, Anna - Havrlentová, Lucia - Janda, Zdeněk - Mazur, Miloslav - Nováková, Zuzana
PY  - 2020
TI  - Psoas density is associated with postoperative mortality after resection for colon cancer
SN  - 9788087339619
KW  - colon cancer, sarcopenia, 30-day mortality
N2  - AIM: to evaluate computed tomography scans of total muscle area and radiation attenutation in patients before resection for colon cancer as a predictive factor for postoperative mortality. METHOD: In this retrospective study we examined 65 patients, who underwent a surgical curative resection for malignant colon carcinoma (mean age 68.5±10.8 years, BMI 28.51±5.9 kg/m2, 30-day mortality was 7.7%). Preoperative computed tomography scans were performed in every patient. We compared postoperative mortality in assotiation with an average psoas density (PD), total psoas muscle area (TPA) and total abdominal muscle area (TMA) at the third lumbar vertebra level. We used Mann-Whitney for statistical testing with 80 % power and the significance level of 0.05. RESULTS: We found statistically significant correlation in the psoas muscle radiation attenuation associated with postoperative 30-day mortality: survival vs. non-survival: PD: 42.7 vs. 34.0 HU, p=0.026. There were non-significant differences in TPA: 8.44 vs. 7.22 cm2/m2, p=0.39 and TMA: 72.66 vs. 71.26 cm2/m2, p=0.71. CONCLUSION: The results show the detectable changes in computed tomography scans associated with 30-day mortality in patients after colon cancer surgery. The significant difference is perceived only between the muscle radiation density and not the muscle area. This is caused by muscle´s fat infiltration, that does not affect the volume of muscle, however its function is impaired. Supported by: This publication was written with the support of the Specific University Research no. MUNI/A/1307/2019 provided by MŠMT.
ER  -

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