ROSLI, Nur Farhanah, Michaela FOJTŮ, Adrian C. FISHER a Martin PUMERA. Graphene Oxide Nanoplatelets Potentiate Anticancer Effect of Cisplatin in Human Lung Cancer Cells. Langmuir. WASHINGTON: AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2019, roč. 35, č. 8, s. 3176-3182. ISSN 0743-7463. Dostupné z: https://dx.doi.org/10.1021/acs.langmuir.8b03086. |
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@article{1612196, author = {Rosli, Nur Farhanah and Fojtů, Michaela and Fisher, Adrian C. and Pumera, Martin}, article_location = {WASHINGTON}, article_number = {8}, doi = {http://dx.doi.org/10.1021/acs.langmuir.8b03086}, keywords = {TARGETED DELIVERY; CYTOTOXICITY; TOXICITY; NANOCARRIER; LABELS}, language = {eng}, issn = {0743-7463}, journal = {Langmuir}, title = {Graphene Oxide Nanoplatelets Potentiate Anticancer Effect of Cisplatin in Human Lung Cancer Cells}, url = {http://dx.doi.org/10.1021/acs.langmuir.8b03086}, volume = {35}, year = {2019} }
TY - JOUR ID - 1612196 AU - Rosli, Nur Farhanah - Fojtů, Michaela - Fisher, Adrian C. - Pumera, Martin PY - 2019 TI - Graphene Oxide Nanoplatelets Potentiate Anticancer Effect of Cisplatin in Human Lung Cancer Cells JF - Langmuir VL - 35 IS - 8 SP - 3176-3182 EP - 3176-3182 PB - AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA SN - 07437463 KW - TARGETED DELIVERY KW - CYTOTOXICITY KW - TOXICITY KW - NANOCARRIER KW - LABELS UR - http://dx.doi.org/10.1021/acs.langmuir.8b03086 L2 - http://dx.doi.org/10.1021/acs.langmuir.8b03086 N2 - Graphene oxide (GO) has been widely explored by many in drug delivery strategies and toxicity assays. The toxicity of graphene oxide depends on the size of the sheets. Smaller sheets show lower toxicity, a quality which is essential for utilization in biomedical applications. However, despite vast research on GO, anticancer properties and drug carrier capabilities of graphene oxide nanoplatelets have yet to be fully explored. Herein, we have uniquely prepared graphene oxide nanoplatelets (GONPs) from well-defined stacked graphite nanofibers (SGNF) with a base of 50 x 50 nm(2) for toxicity and drug potentiation studies when coadministered with the chemotherapeutic drug cisplatin (CP) in human lung cancer cells, A549 cells. Results obtained from our studies have found that not only were GONPs able to act as drug carriers, but they can also significantly potentiate anticancer effect of CP in A549 cells. ER -
ROSLI, Nur Farhanah, Michaela FOJTŮ, Adrian C. FISHER a Martin PUMERA. Graphene Oxide Nanoplatelets Potentiate Anticancer Effect of Cisplatin in Human Lung Cancer Cells. \textit{Langmuir}. WASHINGTON: AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2019, roč.~35, č.~8, s.~3176-3182. ISSN~0743-7463. Dostupné z: https://dx.doi.org/10.1021/acs.langmuir.8b03086.
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