Tuberculosis in Elderly in the Czech Republic

J 2019

Tuberculosis in Elderly in the Czech Republic

FERNANDOVÁ, Emmanuela, Katarína BIELAKOVÁ a Hana MATĚJOVSKÁ KUBEŠOVÁ

Základní údaje

Originální název

Tuberculosis in Elderly in the Czech Republic

Název česky

Tuberkulóza u seniorů v České republice

Autoři

FERNANDOVÁ, Emmanuela (203 Česká republika, garant, domácí), Katarína BIELAKOVÁ (703 Slovensko, domácí) a Hana MATĚJOVSKÁ KUBEŠOVÁ (203 Česká republika, domácí)

Vydání

Epidemiologie, mikrobiologie, imunologie, Praha, ČLS JEP, 2019, 1210-7913

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30203 Respiratory systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.379

Kód RIV

RIV/00216224:14110/19:00112821

Organizační jednotka

Lékařská fakulta

UT WoS

000510477900004

Klíčová slova anglicky

tuberculosis; elderly; Czech Republic; epidemiology; immunity

Štítky

14110228, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 14. 4. 2020 14:38, Mgr. Tereza Miškechová

Anotace

V originále

The incidence of tuberculosis (TB) in the Czech Republic (CR) is decreasing since 1960s. (1965: 76.9; 1975: 60.4; 1985: 45.2; 1995: 17.7; 2005: 9.9; 2015: 4.9 per 100, 000 population). In 2017 men accounted for over than 70% of cases. People aged over 75 years are most frequently affected. Elderly patients tend to develop more of extrapulmonary and atypical manifestation of the disease, the diagnosis of TB can be difficult and consequently overlooked. Multimorbid seniors are suffering from chronic illnesses, malignancies and autoimmune diseases, which translate into higher degree of immunosuppression and add to the generally described process of immunosenescence. Furthermore, therapy of TB in the elderly is challenging because of the increased drug resistance and higher incidence of adverse drug reactions. This article reviews the epidemiology of TB in the CR, immunological aspects, clinical characteristics, diagnosis, management, prevention of TB infection and presents two clinical cases in hospitalized aging adults in the CR.

Návaznosti

MUNI/A/1382/2018, interní kód MU

Název: Optimalizace diagnostických a léčebných metod u multimorbidních seniorů (Akronym: Opdilem)

Investor: Masarykova univerzita, Optimalizace diagnostických a léčebných metod u multimorbidních seniorů, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

FERNANDOVÁ, Emmanuela, Katarína BIELAKOVÁ a Hana MATĚJOVSKÁ KUBEŠOVÁ. Tuberculosis in Elderly in the Czech Republic. Epidemiologie, mikrobiologie, imunologie. Praha: ČLS JEP, 2019, roč. 68, č. 4, s. 184-190. ISSN 1210-7913.

@article{1614116,
   author = {Fernandová, Emmanuela and Bielaková, Katarína and Matějovská Kubešová, Hana},
   article_location = {Praha},
   article_number = {4},
   keywords = {tuberculosis; elderly; Czech Republic; epidemiology; immunity},
   language = {eng},
   issn = {1210-7913},
   journal = {Epidemiologie, mikrobiologie, imunologie},
   title = {Tuberculosis in Elderly in the Czech Republic},
   url = {https://www.prolekare.cz/casopisy/epidemiologie/2019-4-15/tuberculosis-in-elderly-in-the-czech-republic-119840},
   volume = {68},
   year = {2019}
}

TY  - JOUR
ID  - 1614116
AU  - Fernandová, Emmanuela - Bielaková, Katarína - Matějovská Kubešová, Hana
PY  - 2019
TI  - Tuberculosis in Elderly in the Czech Republic
JF  - Epidemiologie, mikrobiologie, imunologie
VL  - 68
IS  - 4
SP  - 184-190
EP  - 184-190
PB  - ČLS JEP
SN  - 12107913
KW  - tuberculosis
KW  - elderly
KW  - Czech Republic
KW  - epidemiology
KW  - immunity
UR  - https://www.prolekare.cz/casopisy/epidemiologie/2019-4-15/tuberculosis-in-elderly-in-the-czech-republic-119840
L2  - https://www.prolekare.cz/casopisy/epidemiologie/2019-4-15/tuberculosis-in-elderly-in-the-czech-republic-119840
N2  - The incidence of tuberculosis (TB) in the Czech Republic (CR) is decreasing since 1960s. (1965: 76.9; 1975: 60.4; 1985: 45.2; 1995: 17.7; 2005: 9.9; 2015: 4.9 per 100, 000 population). In 2017 men accounted for over than 70% of cases. People aged over 75 years are most frequently affected. Elderly patients tend to develop more of extrapulmonary and atypical manifestation of the disease, the diagnosis of TB can be difficult and consequently overlooked. Multimorbid seniors are suffering from chronic illnesses, malignancies and autoimmune diseases, which translate into higher degree of immunosuppression and add to the generally described process of immunosenescence. Furthermore, therapy of TB in the elderly is challenging because of the increased drug resistance and higher incidence of adverse drug reactions. This article reviews the epidemiology of TB in the CR, immunological aspects, clinical characteristics, diagnosis, management, prevention of TB infection and presents two clinical cases in hospitalized aging adults in the CR.
ER  -

FERNANDOVÁ, Emmanuela, Katarína BIELAKOVÁ a Hana MATĚJOVSKÁ KUBEŠOVÁ. Tuberculosis in Elderly in the Czech Republic. \textit{Epidemiologie, mikrobiologie, imunologie}. Praha: ČLS JEP, 2019, roč.~68, č.~4, s.~184-190. ISSN~1210-7913.

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