A review of microscopy-based evidence for the association of
Propionibacterium acnes biofilms in degenerative disc disease
and other diseased human tissue

J 2019

A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue

CAPOOR, Manu, C. BIRKENMAIER, J.C. WANG, A. MCDOWELL, F.S. AHMED et. al.

Základní údaje

Originální název

A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue

Autoři

CAPOOR, Manu (840 Spojené státy, domácí), C. BIRKENMAIER (276 Německo), J.C. WANG (840 Spojené státy), A. MCDOWELL (372 Irsko), F.S. AHMED (50 Bangladéš), H. BRGGEMANN (208 Dánsko), E. COSCIA (840 Spojené státy), D.G. DAVIES (840 Spojené státy), S. OHRT-NISSEN (208 Dánsko), A. RAZ (840 Spojené státy), Filip RŮŽIČKA (203 Česká republika, domácí), J.E. SCHMITZ (840 Spojené státy), V.A. FISCHETTI (840 Spojené státy) a Ondřej SLABÝ (203 Česká republika, garant, domácí)

Vydání

European Spine Journal, NEW YORK, Springer, 2019, 0940-6719

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.458

Kód RIV

RIV/00216224:14740/19:00112970

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1007/s00586-019-06086-y

UT WoS

000499770300002

Klíčová slova anglicky

Acne vulgaris; Arthroscopy; Atherosclerosis; Biofilm; Cutibacterium acnes; Degenerative disc disease; FISH-CLSM; Propionibacterium acnes; Prostate cancer

Štítky

14110113, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 3. 2020 21:09, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

Purpose Recent research shows an increasing recognition that organisms not traditionally considered infectious in nature contribute to disease processes. Propionibacterium acnes (P. acnes) is a gram-positive, aerotolerant anaerobe prevalent in the sebaceous gland-rich areas of the human skin. A ubiquitous slow-growing organism with the capacity to form biofilm, P. acnes, recognized for its role in acne vulgaris and medical device-related infections, is now also linked to a number of other human diseases. While bacterial culture and molecular techniques are used to investigate the involvement of P. acnes in such diseases, definitive demonstration of P. acnes infection requires a technique (or techniques) sensitive to the presence of biofilms and insensitive to the presence of potential contamination. Fortunately, there are imaging techniques meeting these criteria, in particular, fluorescence in situ hybridization and immunofluorescence coupled with confocal laser scanning microscopy, as well as immunohistochemistry. Methods Our literature review considers a range of microscopy-based studies that provides definitive evidence of P. acnes colonization within tissue from a number of human diseases (acne vulgaris, degenerative disc and prostate disease and atherosclerosis), some of which are currently not considered to have an infectious etiology. Results/Conclusion We conclude that P. acnes is an opportunistic pathogen with a likely underestimated role in the development of various human diseases associated with significant morbidity and, in some cases, mortality. As such, these findings offer the potential for new studies aimed at understanding the pathological mechanisms driving the observed disease associations, as well as novel diagnostic strategies and treatment strategies, particularly for degenerative disc disease. Graphic abstract These slides can be retrieved under Electronic Supplementary Material.

Návaznosti

MUNI/A/1189/2018, interní kód MU

Název: Původci nozokomiálních nákaz a možnosti jejich diagnostiky a terapie (Akronym: PNNMDT)

Investor: Masarykova univerzita, Původci nozokomiálních nákaz a možnosti jejich diagnostiky a terapie, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

CAPOOR, Manu, C. BIRKENMAIER, J.C. WANG, A. MCDOWELL, F.S. AHMED, H. BRGGEMANN, E. COSCIA, D.G. DAVIES, S. OHRT-NISSEN, A. RAZ, Filip RŮŽIČKA, J.E. SCHMITZ, V.A. FISCHETTI a Ondřej SLABÝ. A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue. European Spine Journal. NEW YORK: Springer, 2019, roč. 28, č. 12, s. 2951-2971. ISSN 0940-6719. Dostupné z: https://dx.doi.org/10.1007/s00586-019-06086-y.

@article{1623459,
   author = {Capoor, Manu and Birkenmaier, C. and Wang, J.C. and McDowell, A. and Ahmed, F.S. and Brggemann, H. and Coscia, E. and Davies, D.G. and OhrtandNissen, S. and Raz, A. and Růžička, Filip and Schmitz, J.E. and Fischetti, V.A. and Slabý, Ondřej},
   article_location = {NEW YORK},
   article_number = {12},
   doi = {http://dx.doi.org/10.1007/s00586-019-06086-y},
   keywords = {Acne vulgaris; Arthroscopy; Atherosclerosis; Biofilm; Cutibacterium acnes; Degenerative disc disease; FISH-CLSM; Propionibacterium acnes; Prostate cancer},
   language = {eng},
   issn = {0940-6719},
   journal = {European Spine Journal},
   title = {A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue},
   url = {https://link.springer.com/article/10.1007%2Fs00586-019-06086-y#Ack1},
   volume = {28},
   year = {2019}
}

TY  - JOUR
ID  - 1623459
AU  - Capoor, Manu - Birkenmaier, C. - Wang, J.C. - McDowell, A. - Ahmed, F.S. - Brggemann, H. - Coscia, E. - Davies, D.G. - Ohrt-Nissen, S. - Raz, A. - Růžička, Filip - Schmitz, J.E. - Fischetti, V.A. - Slabý, Ondřej
PY  - 2019
TI  - A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue
JF  - European Spine Journal
VL  - 28
IS  - 12
SP  - 2951-2971
EP  - 2951-2971
PB  - Springer
SN  - 09406719
KW  - Acne vulgaris
KW  - Arthroscopy
KW  - Atherosclerosis
KW  - Biofilm
KW  - Cutibacterium acnes
KW  - Degenerative disc disease
KW  - FISH-CLSM
KW  - Propionibacterium acnes
KW  - Prostate cancer
UR  - https://link.springer.com/article/10.1007%2Fs00586-019-06086-y#Ack1
L2  - https://link.springer.com/article/10.1007%2Fs00586-019-06086-y#Ack1
N2  - Purpose Recent research shows an increasing recognition that organisms not traditionally considered infectious in nature contribute to disease processes. Propionibacterium acnes (P. acnes) is a gram-positive, aerotolerant anaerobe prevalent in the sebaceous gland-rich areas of the human skin. A ubiquitous slow-growing organism with the capacity to form biofilm, P. acnes, recognized for its role in acne vulgaris and medical device-related infections, is now also linked to a number of other human diseases. While bacterial culture and molecular techniques are used to investigate the involvement of P. acnes in such diseases, definitive demonstration of P. acnes infection requires a technique (or techniques) sensitive to the presence of biofilms and insensitive to the presence of potential contamination. Fortunately, there are imaging techniques meeting these criteria, in particular, fluorescence in situ hybridization and immunofluorescence coupled with confocal laser scanning microscopy, as well as immunohistochemistry. Methods Our literature review considers a range of microscopy-based studies that provides definitive evidence of P. acnes colonization within tissue from a number of human diseases (acne vulgaris, degenerative disc and prostate disease and atherosclerosis), some of which are currently not considered to have an infectious etiology. Results/Conclusion We conclude that P. acnes is an opportunistic pathogen with a likely underestimated role in the development of various human diseases associated with significant morbidity and, in some cases, mortality. As such, these findings offer the potential for new studies aimed at understanding the pathological mechanisms driving the observed disease associations, as well as novel diagnostic strategies and treatment strategies, particularly for degenerative disc disease. Graphic abstract These slides can be retrieved under Electronic Supplementary Material.
ER  -

CAPOOR, Manu, C. BIRKENMAIER, J.C. WANG, A. MCDOWELL, F.S. AHMED, H. BRGGEMANN, E. COSCIA, D.G. DAVIES, S. OHRT-NISSEN, A. RAZ, Filip RŮŽIČKA, J.E. SCHMITZ, V.A. FISCHETTI a Ondřej SLABÝ. A review of microscopy-based evidence for the association of Propionibacterium acnes biofilms in degenerative disc disease and other diseased human tissue. \textit{European Spine Journal}. NEW YORK: Springer, 2019, roč.~28, č.~12, s.~2951-2971. ISSN~0940-6719. Dostupné z: https://dx.doi.org/10.1007/s00586-019-06086-y.

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