Erectile Dysfunction Treatment Using Focused Linear
Low-Intensity Extracorporeal Shockwaves: Single-Blind,
Sham-Controlled, Randomized Clinical Trial

J 2020

Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial

ŠRÁMKOVÁ, Taťána; Igor MOTIL; Jiří JARKOVSKÝ and Kateřina ŠRÁMKOVÁ

Basic information

Original name

Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial

Authors

ŠRÁMKOVÁ, Taťána (203 Czech Republic, guarantor, belonging to the institution); Igor MOTIL (203 Czech Republic); Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution) and Kateřina ŠRÁMKOVÁ (203 Czech Republic)

Edition

Urologia Internationalis, Basel, Karger, 2020, 0042-1138

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30217 Urology and nephrology

Country of publisher

Switzerland

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Impact factor

Impact factor: 2.089

RIV identification code

RIV/00216224:14110/20:00115341

Organization unit

Faculty of Medicine

DOI

https://doi.org/10.1159/000504788

UT WoS

000543544500014

EID Scopus

2-s2.0-85076703161

Keywords in English

Erectile dysfunction; Cardiovascular disease; Low-intensity extracorporeal shockwave; Phosphodiesterase-5 inhibitors

Abstract

In the original language

Introduction:Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a new treatment modality for erectile dysfunction (ED). Our aim was to evaluate the treatment outcome of Li-ESWT for ED in single-blind, placebo controlled, randomized clinical trial.Methods:Sixty patients were randomized into 2 age-matched groups: Group A - treatment and Group B - placebo. Treatment consisted of 4 sessions on the PiezoWave2 unit (R. Wolf and ELvation Medical). Effectiveness was assessed according to the International Index of Erectile Function 5 (IIEF-5), Erectile Hardness Score (EHS), questions 2 and 3 of the Sexual Encounter Profile (SEP 2, SEP 3), and Global Assessment Question (GAQ) scores at baseline and 4 and 12 weeks after treatment. We evaluated patient's and partner's subjective satisfaction.Results:A statistically significant difference between the groups was found at 4 and 12 weeks after treatment with regard to the quality of erection as measured by the IIEF-5 (p= 0.049 andp< 0.001, respectively), the EHS after week 12 (p< 0.001), an increase in the EHS after 4 and 12 weeks (p= 0.030 andp< 0.001, respectively), after 12 weeks in GAQ (p< 0.001), SEP 2 (p= 0.05), SEP 3 (p< 0.001), and patient's satisfaction (p< 0.001) and partner's satisfaction (p< 0.001).Conclusions:The randomized single-blind study confirms that Li-ESWT significantly improves erectile function.

Cite

ŠRÁMKOVÁ, Taťána; Igor MOTIL; Jiří JARKOVSKÝ and Kateřina ŠRÁMKOVÁ. Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial. Urologia Internationalis. Basel: Karger, 2020, vol. 104, 5-6, p. 417-424. ISSN 0042-1138. Available from: https://doi.org/10.1159/000504788.

@article{1624556,
   author = {Šrámková, Taťána and Motil, Igor and Jarkovský, Jiří and Šrámková, Kateřina},
   article_location = {Basel},
   article_number = {5-6},
   doi = {https://doi.org/10.1159/000504788},
   keywords = {Erectile dysfunction; Cardiovascular disease; Low-intensity extracorporeal shockwave; Phosphodiesterase-5 inhibitors},
   language = {eng},
   issn = {0042-1138},
   journal = {Urologia Internationalis},
   title = {Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial},
   url = {https://www.karger.com/Article/FullText/504788},
   volume = {104},
   year = {2020}
}

TY  - JOUR
ID  - 1624556
AU  - Šrámková, Taťána - Motil, Igor - Jarkovský, Jiří - Šrámková, Kateřina
PY  - 2020
TI  - Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial
JF  - Urologia Internationalis
VL  - 104
IS  - 5-6
SP  - 417-424
EP  - 417-424
PB  - Karger
SN  - 00421138
KW  - Erectile dysfunction
KW  - Cardiovascular disease
KW  - Low-intensity extracorporeal shockwave
KW  - Phosphodiesterase-5 inhibitors
UR  - https://www.karger.com/Article/FullText/504788
L2  - https://www.karger.com/Article/FullText/504788
N2  - Introduction:Low-intensity extracorporeal shock wave therapy (Li-ESWT) is a new treatment modality for erectile dysfunction (ED). Our aim was to evaluate the treatment outcome of Li-ESWT for ED in single-blind, placebo controlled, randomized clinical trial.Methods:Sixty patients were randomized into 2 age-matched groups: Group A - treatment and Group B - placebo. Treatment consisted of 4 sessions on the PiezoWave2 unit (R. Wolf and ELvation Medical). Effectiveness was assessed according to the International Index of Erectile Function 5 (IIEF-5), Erectile Hardness Score (EHS), questions 2 and 3 of the Sexual Encounter Profile (SEP 2, SEP 3), and Global Assessment Question (GAQ) scores at baseline and 4 and 12 weeks after treatment. We evaluated patient's and partner's subjective satisfaction.Results:A statistically significant difference between the groups was found at 4 and 12 weeks after treatment with regard to the quality of erection as measured by the IIEF-5 (p= 0.049 andp< 0.001, respectively), the EHS after week 12 (p< 0.001), an increase in the EHS after 4 and 12 weeks (p= 0.030 andp< 0.001, respectively), after 12 weeks in GAQ (p< 0.001), SEP 2 (p= 0.05), SEP 3 (p< 0.001), and patient's satisfaction (p< 0.001) and partner's satisfaction (p< 0.001).Conclusions:The randomized single-blind study confirms that Li-ESWT significantly improves erectile function.
ER  -

ŠRÁMKOVÁ, Taťána; Igor MOTIL; Jiří JARKOVSKÝ and Kateřina ŠRÁMKOVÁ. Erectile Dysfunction Treatment Using Focused Linear Low-Intensity Extracorporeal Shockwaves: Single-Blind, Sham-Controlled, Randomized Clinical Trial. \textit{Urologia Internationalis}. Basel: Karger, 2020, vol.~104, 5-6, p.~417-424. ISSN~0042-1138. Available from: https://doi.org/10.1159/000504788.

Přehled o publikaci