RUFAQUA, R., M. VRBKA, D. CHOUDHURY, Dušan HEMZAL, I. KRUPKA and M. HARTL. THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT. In Fischer, C Naprstek, J. ENGINEERING MECHANICS 2018 PROCEEDINGS, VOL 24. PRAGUE 9: ACAD SCI CZECH REPUBLIC, INST THEORETICAL & APPLIED MECHANICS, 2018, p. 725-728. ISBN 978-80-86246-88-8. Available from: https://dx.doi.org/10.21495/91-8-725.
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Basic information
Original name THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT
Authors RUFAQUA, R., M. VRBKA, D. CHOUDHURY, Dušan HEMZAL (203 Czech Republic, guarantor, belonging to the institution), I. KRUPKA and M. HARTL.
Edition PRAGUE 9, ENGINEERING MECHANICS 2018 PROCEEDINGS, VOL 24, p. 725-728, 4 pp. 2018.
Publisher ACAD SCI CZECH REPUBLIC, INST THEORETICAL & APPLIED MECHANICS
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 20301 Mechanical engineering
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14310/18:00113181
Organization unit Faculty of Science
ISBN 978-80-86246-88-8
ISSN 1805-8248
Doi http://dx.doi.org/10.21495/91-8-725
UT WoS 000465489800181
Keywords in English synovial fluid; film formation; Raman spectroscopy; bio-tribology; tribo-chemistry
Tags rivok
Tags Reviewed
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 19/4/2020 11:58.
Abstract
The main objective of this study is to clarify the biochemical reactions of the formation of the lubricating film between the head and the cup of the joint replacement. The chemical changes taking place within the proteins of synovial fluid constitute after joint replacements need to be observed. Film formation is also dependent on the pH of the solution and static and rolling conditions, viscosity, concentration of the solution and other mechanical properties of the total environmental condition of joint replacement. The chemical composition of synovial fluid is predominantly considered to explain the development of film on the ball. The experiment was conducted in ball-on-cup configuration in a hip joint simulator, where the ball was made of cobalt chromium molybdenum alloy and the cup was of optical glass. The used proteins albumin, gamma-globulin and bovine serum were the reactants of this process. To analyze the products of the reaction, Raman spectroscopic method was used to observe the changes among proteins. After the analysis of the Raman spectra, it is assumed heterogeneous catalysis process could be taken place on the metal ball during chemical reaction. The results could have significant information regarding lubricating film development within the joint replacement.
Links
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 19/5/2024 23:11