Differences in right-to-left vs left-to-right interventricular
conduction times in patients indicated to cardiac
resynchronization therapy

J 2020

Differences in right-to-left vs left-to-right interventricular conduction times in patients indicated to cardiac resynchronization therapy

POSPÍŠIL, David, Tomáš NOVOTNÝ, Jiří JARKOVSKÝ, Barbora FARKASOVÁ, Milan KOZÁK et. al.

Základní údaje

Originální název

Differences in right-to-left vs left-to-right interventricular conduction times in patients indicated to cardiac resynchronization therapy

Autoři

POSPÍŠIL, David (203 Česká republika, garant, domácí), Tomáš NOVOTNÝ (203 Česká republika, domácí), Jiří JARKOVSKÝ (203 Česká republika, domácí), Barbora FARKASOVÁ (203 Česká republika, domácí), Milan KOZÁK (203 Česká republika, domácí), Lubomír KŘIVAN (203 Česká republika, domácí), Jitka VLAŠÍNOVÁ (203 Česká republika, domácí), Petr KALA (203 Česká republika, domácí) a Milan SEPŠI (203 Česká republika, domácí)

Vydání

PLoS One, San Francisco, Public Library Science, 2020, 1932-6203

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.240

Kód RIV

RIV/00216224:14110/20:00115393

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1371/journal.pone.0228731

UT WoS

000535220600026

Klíčová slova anglicky

ELECTRICAL DELAY; HEART-FAILURE

Štítky

14110211, 14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 2. 2021 15:11, Mgr. Tereza Miškechová

Anotace

V originále

Introduction Differences in conduction times from right ventricle to left ventricle and from left ventricle to right ventricle respectively were observed during biventricular devices implantation when changing pacing vector direction. In this article the phenomenon of interventricular conduction time differences is described and assessed in relationship to various clinical and electrophysiological parameters. Methods In 62 consecutive patients (9 females) interventricular conduction times between right and left ventricle in both directions were measured during cardiac resynchronization therapy device implantation procedure. Complex pacing protocol was performed. Results Investigated individuals was divided into 3 subgroups according to type of interventricular conduction pattern and statistically tested with various clinical data. Substantial differences in right-to-left vs left-to-right conduction times (> 5 ms, range 7-72 ms) were observed in 24 (39%) of all patients. They were more common in patients with dilated cardiomyopathy (20 of 38, 53%) compared to 4 (17%) of 24 patients with coronary artery disease (p = 0.011). The phenomenon occurred more often in hypertensive patients (p = 0.012). Other tested factors were nonsignificant. Conclusions There are almost no data on this topic. The occurrence of conduction difference phenomenon is quite common in dilated cardiomyopathy while it is rare in coronary artery disease. We assume the diffuse nature of the disease and the way of remodeling of myocardium play the main role. Knowledge of this phenomenon could be useful in personalized cardiac resynchronization therapy optimization.

Návaznosti

LM2018128, projekt VaV

Název: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Akronym: CZECRIN)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Český národní uzel Evropské sítě infrastruktur klinického výzkumu (CZECRIN)

MUNI/A/1446/2019, interní kód MU

Název: Nevyřešené otázky a nové metody hodnocení elektrokardiografického signálu (Akronym: ECG2020)

Investor: Masarykova univerzita, Nevyřešené otázky a nové metody hodnocení elektrokardiografického signálu, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

POSPÍŠIL, David, Tomáš NOVOTNÝ, Jiří JARKOVSKÝ, Barbora FARKASOVÁ, Milan KOZÁK, Lubomír KŘIVAN, Jitka VLAŠÍNOVÁ, Petr KALA a Milan SEPŠI. Differences in right-to-left vs left-to-right interventricular conduction times in patients indicated to cardiac resynchronization therapy. PLoS One. San Francisco: Public Library Science, 2020, roč. 15, č. 2, s. 1-8. ISSN 1932-6203. Dostupné z: https://dx.doi.org/10.1371/journal.pone.0228731.

@article{1632520,
   author = {Pospíšil, David and Novotný, Tomáš and Jarkovský, Jiří and Farkasová, Barbora and Kozák, Milan and Křivan, Lubomír and Vlašínová, Jitka and Kala, Petr and Sepši, Milan},
   article_location = {San Francisco},
   article_number = {2},
   doi = {http://dx.doi.org/10.1371/journal.pone.0228731},
   keywords = {ELECTRICAL DELAY; HEART-FAILURE},
   language = {eng},
   issn = {1932-6203},
   journal = {PLoS One},
   title = {Differences in right-to-left vs left-to-right interventricular conduction times in patients indicated to cardiac resynchronization therapy},
   url = {https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0228731&type=printable},
   volume = {15},
   year = {2020}
}

TY  - JOUR
ID  - 1632520
AU  - Pospíšil, David - Novotný, Tomáš - Jarkovský, Jiří - Farkasová, Barbora - Kozák, Milan - Křivan, Lubomír - Vlašínová, Jitka - Kala, Petr - Sepši, Milan
PY  - 2020
TI  - Differences in right-to-left vs left-to-right interventricular conduction times in patients indicated to cardiac resynchronization therapy
JF  - PLoS One
VL  - 15
IS  - 2
SP  - 1-8
EP  - 1-8
PB  - Public Library Science
SN  - 19326203
KW  - ELECTRICAL DELAY
KW  - HEART-FAILURE
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0228731&type=printable
L2  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0228731&type=printable
N2  - Introduction Differences in conduction times from right ventricle to left ventricle and from left ventricle to right ventricle respectively were observed during biventricular devices implantation when changing pacing vector direction. In this article the phenomenon of interventricular conduction time differences is described and assessed in relationship to various clinical and electrophysiological parameters. Methods In 62 consecutive patients (9 females) interventricular conduction times between right and left ventricle in both directions were measured during cardiac resynchronization therapy device implantation procedure. Complex pacing protocol was performed. Results Investigated individuals was divided into 3 subgroups according to type of interventricular conduction pattern and statistically tested with various clinical data. Substantial differences in right-to-left vs left-to-right conduction times (> 5 ms, range 7-72 ms) were observed in 24 (39%) of all patients. They were more common in patients with dilated cardiomyopathy (20 of 38, 53%) compared to 4 (17%) of 24 patients with coronary artery disease (p = 0.011). The phenomenon occurred more often in hypertensive patients (p = 0.012). Other tested factors were nonsignificant. Conclusions There are almost no data on this topic. The occurrence of conduction difference phenomenon is quite common in dilated cardiomyopathy while it is rare in coronary artery disease. We assume the diffuse nature of the disease and the way of remodeling of myocardium play the main role. Knowledge of this phenomenon could be useful in personalized cardiac resynchronization therapy optimization.
ER  -

POSPÍŠIL, David, Tomáš NOVOTNÝ, Jiří JARKOVSKÝ, Barbora FARKASOVÁ, Milan KOZÁK, Lubomír KŘIVAN, Jitka VLAŠÍNOVÁ, Petr KALA a Milan SEPŠI. Differences in right-to-left vs left-to-right interventricular conduction times in patients indicated to cardiac resynchronization therapy. \textit{PLoS One}. San Francisco: Public Library Science, 2020, roč.~15, č.~2, s.~1-8. ISSN~1932-6203. Dostupné z: https://dx.doi.org/10.1371/journal.pone.0228731.

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