| FOSBOL, E.L., L.P. PARK, V.H. CHU, E. ATHAN, F. DELAHAYE, Tomáš FREIBERGER, C. LAMAS, J.M. MIRO, J. STRAHILEVITZ, C. TRIBOUILLOY, E. DURANTE-MANGONI, J.M. PERICAS, N. FERNANDEZ-HIDALGO, F. NACINOVICH, H. RIZK, B. BARSIC, E. GIANNITSIOTI, J.P. HURLEY, M.M. HANNAN, A. WANG, L. CLARA, M. SANCHEZ, J.P. CASABE, F. NACINOVICH, P.F. OSES, R. RONDEROS, A. SUCARI, J. THIERER, J. ALTCLAS, S. KOGAN, D. SPELMAN, E. ATHAN, O. HARRIS, K. KENNEDY, R. TAN, D. GORDON, L. PAPANICOLAS, T. KORMAN, D. KOTSANAS, R. DEVER, P. JONES, P. KONECNY, R. LAWRENCE, D. REES, S. RYAN, M.P. FENELEY, J. HARKNESS, P. JONES, S. RYAN, P. JONES, S. RYAN, P. JONES, J. POST, P. REINBOTT, S. RYAN, R. GATTRINGER, F. WIESBAUER, A.R. ANDRADE, A.C.P. DE BRITO, A.C. GUIMARAES, M. GRINBERG, A.J. MANSUR, R.F. SICILIANO, T.M.V. STRABELLI, M.L.C. VIEIRA, R.A.D. TRANCHESI, M.G. PAIVA, C.Q. FORTES, A.D. RAMOS, C. WEKSLER, G. FERRAIUOLI, W. GOLEBIOVSKI, C. LAMAS, C.J.A. KARLOWSKY, Y. KEYNAN, A.M. MORRIS, E. RUBINSTEIN, S.B. JONES, P. GARCIA, M. CERECEDA, A. FICA, R.M. MELLA, R. FERNANDEZ, L. FRANCO, J. GONZALEZ, A.N. JARAMILLO, B. BARSIC, S. BUKOVSKI, V. KRAJINOVIC, A. PANGERCIC, I. RUDEZ, J. VINCELJ, Tomáš FREIBERGER, J. POL, B. ZALOUDIKOVA, Z. ASHOUR, A. ELKHOLY, M. MISHAAL, D. OSAMA, H. RIZK, N. AISSA, C. ALAUZET, F. ALLA, C. CAMPAGNAC, T. DOCO-LECOMPTE, C. SELTON-SUTY, J.P. CASALTA, P.E. FOURNIER, G. HABIB, D. RAOULT, F. THUNY, F. DELAHAYE, A. DELAHAYE, F. VANDENESCH, E. DONAL, P.Y. DONNIO, E. FLECHER, C. MICHELET, M. REVEST, P. TATTEVIN, F. CHEVALIER, A. JEU, J.P. REMADI, D. RUSINARU, C. TRIBOUILLOY, Y. BERNARD, C. CHIROUZE, B. HOEN, J. LEROY, P. PLESIAT, C. NABER, C. NEUERBURG, B. MAZAHERI, C. NABER, S. ATHANASIA, I. DELIOLANIS, H. GIAMARELLOU, T. THOMAS, E. GIANNITSIOTI, E. MYLONA, O. PANIARA, K. PAPANICOLAOU, J. PYROS, A. SKOUTELIS, E. MYLONA, O. PANIARA, K. PAPANIKOLAOU, J. PYROS, A. SKOUTELIS, G. SHARMA, J. FRANCIS, L. NAIR, V. THOMAS, K. VENUGOPAL, M.M. HANNAN, J.P. HURLEY, A. CAHAN, D. GILON, S. ISRAEL, M. KOREM, J. STRAHILEVITZ, E. RUBINSTEIN, J. STRAHILEVITZ, E. DURANTE-MANGONI, I. MATTUCCI, D. PINTO, F. AGRUSTA, A. SENESE, E. RAGONE, R. UTILI, E. CECCHI, F. DEROSA, D. FORNO, M. IMAZIO, R. TRINCHERO, P. GROSSI, M. LATTANZIO, A. TONIOLO, A. GOGLIO, A. RAGLIO, V. RAVASIO, M. RIZZI, F. SUTER, G. CAROSI, S. MAGRI, L. SIGNORINI, Z. KANAFANI, S.S. KANJ, A. SHARIF-YAKAN, I. ABIDIN, S.S. TAMIN, E.R. MARTINEZ, G.I.S. NIETO, J.T.M. VAN DER MEER, S. CHAMBERS, D. HOLLAND, A. MORRIS, N. RAYMOND, K. READ, D.R. MURDOCH, S. DRAGULESCU, A. IONAC, C. MORNOS, O.M. BUTKEVICH, N. CHIPIGINA, O. KIRILL, K. VADIM, T. VINOGRADOVA, J. EDATHODU, M. HALIM, Y.Y. LIEW, R.S. TAN, T. LEJKO-ZUPANC, M. LOGAR, M. MUELLER-PREMRU, P. COMMERFORD, A. COMMERFORD, E. DEETLEFS, C. HANSA, M. NTSEKHE, M. ALMELA, Y. ARMERO, M. AZQUETA, X. CASTANEDA, C. CERVERA, C. FALCES, C.G. DE-LA-MARIA, G. FITA, J.M. GATELL, M. HERAS, J. LLOPIS, F. MARCO, C.A. MESTRES, J.M. MIRO, A. MORENO, S. NINOT, C. PARE, J.M. PERICAS, J. RAMIREZ, I. ROVIRA, M. SITGES, I. ANGUERA, B. FONT, J.R. GUMA, J. BERMEJO, E. BOUZA, M.A.G. FERNANDEZ, V. GONZALEZ-RAMALLO, M. MARIN, P. MUNOZ, M. PEDROMINGO, J. RODA, M. RODRIGUEZ-CREIXEMS, J. SOLIS, B. ALMIRANTE, N. FERNANDEZ-HIDALGO, P. TORNOS, A. DE ALARCON, R. PARRA, E. ALESTIG, M. JOHANSSON, L. OLAISON, U. SNYGG-MARTIN, O. PACHIRAT, P. PACHIRAT, B. PUSSADHAMMA, V. SENTHONG, A. CASEY, T. ELLIOTT, P. LAMBERT, R. WATKIN, C. EYTON, J.L. KLEIN, S. BRADLEY, C. KAUFFMAN, R. BEDIMO, V.H. CHU, G.R. COREY, A.L. CROWLEY, P. DOUGLAS, L. DREW, V.G. FOWLER, T. HOLLAND, T. LALANI, D. MUDRICK, Z. SAMAD, D. SEXTON, M. STRYJEWSKI, A. WANG, C.W. WOODS, S. LERAKIS, R. CANTEY, L. STEED, D. WRAY, S.A. DICKERMAN, H. BONILLA, J. DIPERSIO, S.J. SALSTROM, J. BADDLEY, M. PATEL, G. PETERSON, A. STANCOVEN, D. LEVINE, J. RIDDLE a M. RYBAK. The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis. European heart journal. Oxford: Oxford University Press, 2019, roč. 40, č. 27, s. 2243-2251. ISSN 0195-668X. Dostupné z: https://dx.doi.org/10.1093/eurheartj/ehz204. |
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@article{1637999,
author = {Fosbol, E.L. and Park, L.P. and Chu, V.H. and Athan, E. and Delahaye, F. and Freiberger, Tomáš and Lamas, C. and Miro, J.M. and Strahilevitz, J. and Tribouilloy, C. and DuranteandMangoni, E. and Pericas, J.M. and FernandezandHidalgo, N. and Nacinovich, F. and Rizk, H. and Barsic, B. and Giannitsioti, E. and Hurley, J.P. and Hannan, M.M. and Wang, A. and Clara, L. and Sanchez, M. and Casabe, J.P. and Nacinovich, F. and Oses, P.F. and Ronderos, R. and Sucari, A. and Thierer, J. and Altclas, J. and Kogan, S. and Spelman, D. and Athan, E. and Harris, O. and Kennedy, K. and Tan, R. and Gordon, D. and Papanicolas, L. and Korman, T. and Kotsanas, D. and Dever, R. and Jones, P. and Konecny, P. and Lawrence, R. and Rees, D. and Ryan, S. and Feneley, M.P. and Harkness, J. and Jones, P. and Ryan, S. and Jones, P. and Ryan, S. and Jones, P. and Post, J. and Reinbott, P. and Ryan, S. and Gattringer, R. and Wiesbauer, F. and Andrade, A.R. and de Brito, A.C.P. and Guimaraes, A.C. and Grinberg, M. and Mansur, A.J. and Siciliano, R.F. and Strabelli, T.M.V. and Vieira, M.L.C. and Tranchesi, R.A.D. and Paiva, M.G. and Fortes, C.Q. and Ramos, A.D. and Weksler, C. and Ferraiuoli, G. and Golebiovski, W. and Lamas, C. and Karlowsky, C.J.A. and Keynan, Y. and Morris, A.M. and Rubinstein, E. and Jones, S.B. and Garcia, P. and Cereceda, M. and Fica, A. and Mella, R.M. and Fernandez, R. and Franco, L. and Gonzalez, J. and Jaramillo, A.N. and Barsic, B. and Bukovski, S. and Krajinovic, V. and Pangercic, A. and Rudez, I. and Vincelj, J. and Freiberger, Tomáš and Pol, J. and Zaloudikova, B. and Ashour, Z. and ElKholy, A. and Mishaal, M. and Osama, D. and Rizk, H. and Aissa, N. and Alauzet, C. and Alla, F. and Campagnac, C. and DocoandLecompte, T. and SeltonandSuty, C. and Casalta, J.P. and Fournier, P.E. and Habib, G. and Raoult, D. and Thuny, F. and Delahaye, F. and Delahaye, A. and Vandenesch, F. and Donal, E. and Donnio, P.Y. and Flecher, E. and Michelet, C. and Revest, M. and Tattevin, P. and Chevalier, F. and Jeu, A. and Remadi, J.P. and Rusinaru, D. and Tribouilloy, C. and Bernard, Y. and Chirouze, C. and Hoen, B. and Leroy, J. and Plesiat, P. and Naber, C. and Neuerburg, C. and Mazaheri, B. and Naber, C. and Athanasia, S. and Deliolanis, I. and Giamarellou, H. and Thomas, T. and Giannitsioti, E. and Mylona, E. and Paniara, O. and Papanicolaou, K. and Pyros, J. and Skoutelis, A. and Mylona, E. and Paniara, O. and Papanikolaou, K. and Pyros, J. and Skoutelis, A. and Sharma, G. and Francis, J. and Nair, L. and Thomas, V. and Venugopal, K. and Hannan, M.M. and Hurley, J.P. and Cahan, A. and Gilon, D. and Israel, S. and Korem, M. and Strahilevitz, J. and Rubinstein, E. and Strahilevitz, J. and DuranteandMangoni, E. and Mattucci, I. and Pinto, D. and Agrusta, F. and Senese, A. and Ragone, E. and Utili, R. and Cecchi, E. and DeRosa, F. and Forno, D. and Imazio, M. and Trinchero, R. and Grossi, P. and Lattanzio, M. and Toniolo, A. and Goglio, A. and Raglio, A. and Ravasio, V. and Rizzi, M. and Suter, F. and Carosi, G. and Magri, S. and Signorini, L. and Kanafani, Z. and Kanj, S.S. and SharifandYakan, A. and Abidin, I. and Tamin, S.S. and Martinez, E.R. and Nieto, G.I.S. and van der Meer, J.T.M. and Chambers, S. and Holland, D. and Morris, A. and Raymond, N. and Read, K. and Murdoch, D.R. and Dragulescu, S. and Ionac, A. and Mornos, C. and Butkevich, O.M. and Chipigina, N. and Kirill, O. and Vadim, K. and Vinogradova, T. and Edathodu, J. and Halim, M. and Liew, Y.Y. and Tan, R.S. and LejkoandZupanc, T. and Logar, M. and MuellerandPremru, M. and Commerford, P. and Commerford, A. and Deetlefs, E. and Hansa, C. and Ntsekhe, M. and Almela, M. and Armero, Y. and Azqueta, M. and Castaneda, X. and Cervera, C. and Falces, C. and deandlaandMaria, C.G. and Fita, G. and Gatell, J.M. and Heras, M. and Llopis, J. and Marco, F. and Mestres, C.A. and Miro, J.M. and Moreno, A. and Ninot, S. and Pare, C. and Pericas, J.M. and Ramirez, J. and Rovira, I. and Sitges, M. and Anguera, I. et al.},
article_location = {Oxford},
article_number = {27},
doi = {http://dx.doi.org/10.1093/eurheartj/ehz204},
keywords = {Infective endocarditis; Vegetation size; Surgery; Antibiotics; Outcomes},
language = {eng},
issn = {0195-668X},
journal = {European heart journal},
title = {The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis},
url = {https://academic.oup.com/eurheartj/article-abstract/40/27/2243/5449384?redirectedFrom=fulltext},
volume = {40},
year = {2019}
}
TY - JOUR
ID - 1637999
AU - Fosbol, E.L. - Park, L.P. - Chu, V.H. - Athan, E. - Delahaye, F. - Freiberger, Tomáš - Lamas, C. - Miro, J.M. - Strahilevitz, J. - Tribouilloy, C. - Durante-Mangoni, E. - Pericas, J.M. - Fernandez-Hidalgo, N. - Nacinovich, F. - Rizk, H. - Barsic, B. - Giannitsioti, E. - Hurley, J.P. - Hannan, M.M. - Wang, A. - Clara, L. - Sanchez, M. - Casabe, J.P. - Nacinovich, F. - Oses, P.F. - Ronderos, R. - Sucari, A. - Thierer, J. - Altclas, J. - Kogan, S. - Spelman, D. - Athan, E. - Harris, O. - Kennedy, K. - Tan, R. - Gordon, D. - Papanicolas, L. - Korman, T. - Kotsanas, D. - Dever, R. - Jones, P. - Konecny, P. - Lawrence, R. - Rees, D. - Ryan, S. - Feneley, M.P. - Harkness, J. - Jones, P. - Ryan, S. - Jones, P. - Ryan, S. - Jones, P. - Post, J. - Reinbott, P. - Ryan, S. - Gattringer, R. - Wiesbauer, F. - Andrade, A.R. - de Brito, A.C.P. - Guimaraes, A.C. - Grinberg, M. - Mansur, A.J. - Siciliano, R.F. - Strabelli, T.M.V. - Vieira, M.L.C. - Tranchesi, R.A.D. - Paiva, M.G. - Fortes, C.Q. - Ramos, A.D. - Weksler, C. - Ferraiuoli, G. - Golebiovski, W. - Lamas, C. - Karlowsky, C.J.A. - Keynan, Y. - Morris, A.M. - Rubinstein, E. - Jones, S.B. - Garcia, P. - Cereceda, M. - Fica, A. - Mella, R.M. - Fernandez, R. - Franco, L. - Gonzalez, J. - Jaramillo, A.N. - Barsic, B. - Bukovski, S. - Krajinovic, V. - Pangercic, A. - Rudez, I. - Vincelj, J. - Freiberger, Tomáš - Pol, J. - Zaloudikova, B. - Ashour, Z. - ElKholy, A. - Mishaal, M. - Osama, D. - Rizk, H. - Aissa, N. - Alauzet, C. - Alla, F. - Campagnac, C. - Doco-Lecompte, T. - Selton-Suty, C. - Casalta, J.P. - Fournier, P.E. - Habib, G. - Raoult, D. - Thuny, F. - Delahaye, F. - Delahaye, A. - Vandenesch, F. - Donal, E. - Donnio, P.Y. - Flecher, E. - Michelet, C. - Revest, M. - Tattevin, P. - Chevalier, F. - Jeu, A. - Remadi, J.P. - Rusinaru, D. - Tribouilloy, C. - Bernard, Y. - Chirouze, C. - Hoen, B. - Leroy, J. - Plesiat, P. - Naber, C. - Neuerburg, C. - Mazaheri, B. - Naber, C. - Athanasia, S. - Deliolanis, I. - Giamarellou, H. - Thomas, T. - Giannitsioti, E. - Mylona, E. - Paniara, O. - Papanicolaou, K. - Pyros, J. - Skoutelis, A. - Mylona, E. - Paniara, O. - Papanikolaou, K. - Pyros, J. - Skoutelis, A. - Sharma, G. - Francis, J. - Nair, L. - Thomas, V. - Venugopal, K. - Hannan, M.M. - Hurley, J.P. - Cahan, A. - Gilon, D. - Israel, S. - Korem, M. - Strahilevitz, J. - Rubinstein, E. - Strahilevitz, J. - Durante-Mangoni, E. - Mattucci, I. - Pinto, D. - Agrusta, F. - Senese, A. - Ragone, E. - Utili, R. - Cecchi, E. - DeRosa, F. - Forno, D. - Imazio, M. - Trinchero, R. - Grossi, P. - Lattanzio, M. - Toniolo, A. - Goglio, A. - Raglio, A. - Ravasio, V. - Rizzi, M. - Suter, F. - Carosi, G. - Magri, S. - Signorini, L. - Kanafani, Z. - Kanj, S.S. - Sharif-Yakan, A. - Abidin, I. - Tamin, S.S. - Martinez, E.R. - Nieto, G.I.S. - van der Meer, J.T.M. - Chambers, S. - Holland, D. - Morris, A. - Raymond, N. - Read, K. - Murdoch, D.R. - Dragulescu, S. - Ionac, A. - Mornos, C. - Butkevich, O.M. - Chipigina, N. - Kirill, O. - Vadim, K. - Vinogradova, T. - Edathodu, J. - Halim, M. - Liew, Y.Y. - Tan, R.S. - Lejko-Zupanc, T. - Logar, M. - Mueller-Premru, M. - Commerford, P. - Commerford, A. - Deetlefs, E. - Hansa, C. - Ntsekhe, M. - Almela, M. - Armero, Y. - Azqueta, M. - Castaneda, X. - Cervera, C. - Falces, C. - de-la-Maria, C.G. - Fita, G. - Gatell, J.M. - Heras, M. - Llopis, J. - Marco, F. - Mestres, C.A. - Miro, J.M. - Moreno, A. - Ninot, S. - Pare, C. - Pericas, J.M. - Ramirez, J. - Rovira, I. - Sitges, M. - Anguera, I. et al.
PY - 2019
TI - The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis
JF - European heart journal
VL - 40
IS - 27
SP - 2243-2251
EP - 2243-2251
PB - Oxford University Press
SN - 0195668X
KW - Infective endocarditis
KW - Vegetation size
KW - Surgery
KW - Antibiotics
KW - Outcomes
UR - https://academic.oup.com/eurheartj/article-abstract/40/27/2243/5449384?redirectedFrom=fulltext
L2 - https://academic.oup.com/eurheartj/article-abstract/40/27/2243/5449384?redirectedFrom=fulltext
N2 - Aims In left-sided infective endocarditis (IE), a large vegetation >10mm is associated with higher mortality, yet it is unknown whether surgery during the acute phase opposed to medical therapy is associated with improved survival. We assessed the association between surgery and 6-month mortality as related to vegetation size. Methods and results Patients with definite, left-sided IE (2008-2012) from The International Collaboration on Endocarditis prospective, multinational registry were included. We compared clinical characteristics and 6-month mortality (by Cox regression with inverse propensity of treatment weighting) between patients with vegetation size <= 10mm vs. >10mm in maximum length by surgical treatment strategy. A total of 1006 patients with left sided IE were included; 422 with a vegetation size <= 10mm (median age 66.0 years, 33% women) and 584 (median age 58.4 years, 34% women) patients with a large vegetation >10 mm. Operative risk by STS-IE score was similar between groups. Embolic events occurred in 28.4% vs. 44.3% (P < 0.001), respectively. Patients with a vegetation >10mm was associated with higher 6-month mortality (25.1% vs. 19.4% for small vegetation, P = 0.035). However, after propensity adjustment, the association with higher mortality persisted only in patients with a large vegetation >10mm vs. <= 10 mm: hazard ratio (HR) 1.55 (1.27-1.90); but only in patients with large vegetation managed medically [HR 1.86 (1.48-2.34)] rather than surgically [HR 1.01 (0.69-1.49)]. Conclusion Left-sided IE with vegetation size >10mm was associated with an increased mortality at 6 months in this observational study but was dependent on treatment strategy. For patients with large vegetation undergoing surgical treatment, survival was similar to patients with smaller vegetation size.
ER -
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