| SCHIRMER, K., J. STADNICKA-MICHALAK, S.E. BELANGER, Luděk BLÁHA, N.C. BOLS, S.D. DYER, M.R. EMBRY, M. FISCHER, M. HAIDER, J. HERMENS, M.T. HULTMAN, N. KRAMER, H. LAUE, L.E.J. LEE, A. LILLICRAP, A. NATSCH, H. SEGNER, K. TANNEBERGER, K.E. TOLLEFSEN, I. WERNER, H. WITTERS a A. ZUPANIC. Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482. Environmental Pollution. OXFORD, OXON, ENGLAND: ELSEVIER SCI LTD, 2019, roč. 254, NOV 2019, s. 1-3. ISSN 0269-7491. Dostupné z: https://dx.doi.org/10.1016/j.envpol.2019.113060. |
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@article{1641576,
author = {Schirmer, K. and StadnickaandMichalak, J. and Belanger, S.E. and Bláha, Luděk and Bols, N.C. and Dyer, S.D. and Embry, M.R. and Fischer, M. and Haider, M. and Hermens, J. and Hultman, M.T. and Kramer, N. and Laue, H. and Lee, L.E.J. and Lillicrap, A. and Natsch, A. and Segner, H. and Tanneberger, K. and Tollefsen, K.E. and Werner, I. and Witters, H. and Zupanic, A.},
article_location = {OXFORD, OXON, ENGLAND},
article_number = {NOV 2019},
doi = {http://dx.doi.org/10.1016/j.envpol.2019.113060},
keywords = {Metabolic activation},
language = {eng},
issn = {0269-7491},
journal = {Environmental Pollution},
title = {Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482},
url = {https://www.sciencedirect.com/science/article/pii/S0269749119337893?via%3Dihub},
volume = {254},
year = {2019}
}
TY - JOUR
ID - 1641576
AU - Schirmer, K. - Stadnicka-Michalak, J. - Belanger, S.E. - Bláha, Luděk - Bols, N.C. - Dyer, S.D. - Embry, M.R. - Fischer, M. - Haider, M. - Hermens, J. - Hultman, M.T. - Kramer, N. - Laue, H. - Lee, L.E.J. - Lillicrap, A. - Natsch, A. - Segner, H. - Tanneberger, K. - Tollefsen, K.E. - Werner, I. - Witters, H. - Zupanic, A.
PY - 2019
TI - Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482
JF - Environmental Pollution
VL - 254
IS - NOV 2019
SP - 1-3
EP - 1-3
PB - ELSEVIER SCI LTD
SN - 02697491
KW - Metabolic activation
UR - https://www.sciencedirect.com/science/article/pii/S0269749119337893?via%3Dihub
L2 - https://www.sciencedirect.com/science/article/pii/S0269749119337893?via%3Dihub
N2 - We would like to express strong concerns about the publication by Rodrigues et al., entitled: “Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides”, which was recently published in “Environmental Pollution” (2019, 252, pages 476–482, accepted May 07/2019, available online May 27/2019). The topic of the paper is of great interest to the toxicology community because it addresses the need to define alternatives to animals in chemical risk assessment. The authors collected a large amount of in vitro data on chemical testing and added some of their own – the entire data set being predominantly focused on mammalian cell systems - and then attempted a comparison with data for the same chemicals regarding their toxicity to fish. Unfortunately, the work presented is flawed in several ways, sending an undifferentiated, if not wrong, message. Because we fear that this publication can cause unjustified damage to the achievements already made and to the ongoing efforts of the growing community in academia, industry and regulation to further alternatives to animal testing, we wish to openly discuss our concerns.
ER -
SCHIRMER, K., J. STADNICKA-MICHALAK, S.E. BELANGER, Luděk BLÁHA, N.C. BOLS, S.D. DYER, M.R. EMBRY, M. FISCHER, M. HAIDER, J. HERMENS, M.T. HULTMAN, N. KRAMER, H. LAUE, L.E.J. LEE, A. LILLICRAP, A. NATSCH, H. SEGNER, K. TANNEBERGER, K.E. TOLLEFSEN, I. WERNER, H. WITTERS a A. ZUPANIC. Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482. \textit{Environmental Pollution}. OXFORD, OXON, ENGLAND: ELSEVIER SCI LTD, 2019, roč.~254, NOV 2019, s.~1-3. ISSN~0269-7491. Dostupné z: https://dx.doi.org/10.1016/j.envpol.2019.113060.
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