Comparison of whole exome sequencing and FoundationOne Heme
sequencing panel as tools for precision oncology in paediatric
patients with difficult-to-treat solid tumours

a 2019

Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours

NOSKOVA, H., Soňa ADAMCOVÁ, Dana KNOFLÍČKOVÁ, Karol PÁL, Andrea GRIONI et. al.

Základní údaje

Originální název

Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours

Autoři

NOSKOVA, H., Soňa ADAMCOVÁ (703 Slovensko, domácí), Dana KNOFLÍČKOVÁ (203 Česká republika, domácí), Karol PÁL (703 Slovensko, domácí), Andrea GRIONI (380 Itálie, domácí), T. HORNAKOVA, T. MERTA, P. MUDRY, Z. PAVELKA, K. VEJMELKOVA, J. STERBA a Ondřej SLABÝ (203 Česká republika, garant, domácí)

Vydání

Conference on Molecular Analysis for Personalised Therapy (MAP), 2019

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30204 Oncology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 18.274

Kód RIV

RIV/00216224:14740/19:00108620

Organizační jednotka

Středoevropský technologický institut

ISSN

DOI

http://dx.doi.org/10.1093/annonc/mdz413.102

UT WoS

000496763900096

Klíčová slova anglicky

exome sequencing

Štítky

rivok

Příznaky

Mezinárodní význam

Změněno: 3. 4. 2020 19:42, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

The necessary condition for the application of precision oncology approach into the routine is a detailed molecular characterization of the tumour. In our study, we explored clinical applicability of both whole exome sequencing (WES) and FoundationOne Heme (F1Heme) panel (Foundation Medicine, Inc., MA, USA) as comprehensive genomic profiling tools in a cohort of 35 children with difficult-to-treat solid tumours.

Návaznosti

NV16-33209A, projekt VaV

Název: Sekvenování nové generace a expresní profilování jako diagnostický podklad pro návrhy individualizovaných léčebných plánů pro děti se solidními nádory

Citovat

NOSKOVA, H., Soňa ADAMCOVÁ, Dana KNOFLÍČKOVÁ, Karol PÁL, Andrea GRIONI, T. HORNAKOVA, T. MERTA, P. MUDRY, Z. PAVELKA, K. VEJMELKOVA, J. STERBA a Ondřej SLABÝ. Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours. In Conference on Molecular Analysis for Personalised Therapy (MAP). 2019. ISSN 0923-7534. Dostupné z: https://dx.doi.org/10.1093/annonc/mdz413.102.

@proceedings{1642620,
   author = {Noskova, H. and Adamcová, Soňa and Knoflíčková, Dana and Pál, Karol and Grioni, Andrea and Hornakova, T. and Merta, T. and Mudry, P. and Pavelka, Z. and Vejmelkova, K. and Sterba, J. and Slabý, Ondřej},
   booktitle = {Conference on Molecular Analysis for Personalised Therapy (MAP)},
   doi = {http://dx.doi.org/10.1093/annonc/mdz413.102},
   keywords = {exome sequencing},
   language = {eng},
   title = {Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours},
   year = {2019}
}

TY  - CONF
ID  - 1642620
AU  - Noskova, H. - Adamcová, Soňa - Knoflíčková, Dana - Pál, Karol - Grioni, Andrea - Hornakova, T. - Merta, T. - Mudry, P. - Pavelka, Z. - Vejmelkova, K. - Sterba, J. - Slabý, Ondřej
PY  - 2019
TI  - Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours
KW  - exome sequencing
N2  - The necessary condition for the application of precision oncology approach into the routine is a detailed molecular characterization of the tumour. In our study, we explored clinical applicability of both whole exome sequencing (WES) and FoundationOne Heme (F1Heme) panel (Foundation Medicine, Inc., MA, USA) as comprehensive genomic profiling tools in a cohort of 35 children with difficult-to-treat solid tumours.
ER  -

NOSKOVA, H., Soňa ADAMCOVÁ, Dana KNOFLÍČKOVÁ, Karol PÁL, Andrea GRIONI, T. HORNAKOVA, T. MERTA, P. MUDRY, Z. PAVELKA, K. VEJMELKOVA, J. STERBA a Ondřej SLABÝ. Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours. In \textit{Conference on Molecular Analysis for Personalised Therapy (MAP)}. 2019. ISSN~0923-7534. Dostupné z: https://dx.doi.org/10.1093/annonc/mdz413.102.

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