| GREGOROVÁ, Jana, Lenka RADOVÁ, Natalia Anna GABŁO, M. ALMASI, M. STORK, Ondřej SLABÝ, L. POUR, J. MINARIK a Sabina ŠEVČÍKOVÁ. MicroRNA analysis in multiple myeloma and extramedullary disease. In 17th International Myeloma Workshop. 2019. ISSN 2152-2650. Dostupné z: https://dx.doi.org/10.1016/j.clml.2019.09.103. |
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@proceedings{1642622,
author = {Gregorová, Jana and Radová, Lenka and Gabło, Natalia Anna and Almasi, M. and Stork, M. and Slabý, Ondřej and Pour, L. and Minarik, J. and Ševčíková, Sabina},
booktitle = {17th International Myeloma Workshop},
doi = {http://dx.doi.org/10.1016/j.clml.2019.09.103},
keywords = {extramedullary disease; microRNA; Next Generation Sequencing},
language = {eng},
title = {MicroRNA analysis in multiple myeloma and extramedullary disease},
year = {2019}
}
TY - CONF
ID - 1642622
AU - Gregorová, Jana - Radová, Lenka - Gabło, Natalia Anna - Almasi, M. - Stork, M. - Slabý, Ondřej - Pour, L. - Minarik, J. - Ševčíková, Sabina
PY - 2019
TI - MicroRNA analysis in multiple myeloma and extramedullary disease
KW - extramedullary disease
KW - microRNA
KW - Next Generation Sequencing
N2 - MicroRNAs (miRNAs) are short non-coding RNA molecules that are involved in many physiological and pathological processes. Multiple myeloma (MM) is the second most common hematological malignancy of plasma cells (PCs). Survival of patients is negatively affected by extramedullary disease (EM). EM occurs when PCs migrate out of the bone marrow (BM) and lose the dependence to its microenvironment. The mechanism by which the EM occurs is not yet elucidated. The importance of miRNA in the pathogenesis of MM has been demonstrated by several studies. We assume that they are involved in the development of EM. Aims: The aim of this work was to analyze different expression of miRNA in BM PCs of EM vs MM patients.
ER -
GREGOROVÁ, Jana, Lenka RADOVÁ, Natalia Anna GABŁO, M. ALMASI, M. STORK, Ondřej SLABÝ, L. POUR, J. MINARIK a Sabina ŠEVČÍKOVÁ. MicroRNA analysis in multiple myeloma and extramedullary disease. In \textit{17th International Myeloma Workshop}. 2019. ISSN~2152-2650. Dostupné z: https://dx.doi.org/10.1016/j.clml.2019.09.103.
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