ANYZ, J., L. VYSLOUZILOVA, V. HORAK, O. STEPANKOVA, Tomáš VACULOVIČ and V. ADAM. Examination of the Spatial Structure of Pigs' Melanoma in Tissue Sections Based on Histology and Mass Spectrometry. In Lhotska, L Sukupova, L Lackovic, I Ibbott, GS. WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2018, VOL 1. NEW YORK: SPRINGER, 2019, p. 255-259. ISBN 978-981-10-9034-9. Available from: https://dx.doi.org/10.1007/978-981-10-9035-6_46.
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Basic information
Original name Examination of the Spatial Structure of Pigs' Melanoma in Tissue Sections Based on Histology and Mass Spectrometry
Authors ANYZ, J. (guarantor), L. VYSLOUZILOVA, V. HORAK, O. STEPANKOVA, Tomáš VACULOVIČ (203 Czech Republic, belonging to the institution) and V. ADAM.
Edition NEW YORK, WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2018, VOL 1, p. 255-259, 5 pp. 2019.
Publisher SPRINGER
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 20600 2.6 Medical engineering
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14310/19:00113731
Organization unit Faculty of Science
ISBN 978-981-10-9034-9
ISSN 1680-0737
Doi http://dx.doi.org/10.1007/978-981-10-9035-6_46
UT WoS 000450908300046
Keywords in English Clustering; Image processing; MeLiM; Melanoma 2D maximum overlap wavelet transform
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 11/5/2020 18:34.
Abstract
We examine the spatial structure of the melanoma in tissue sections. The pigs melanoma was examined in 10 tissue samples obtained from animals of age between 4 and 22 weeks. The tissue sections were measured by light microscopy and Laser Ablation Ion Inductively Coupled Plasma Mass Spectrometry to obtain spatial metal (Cu, Zn) distribution. The exploratory analysis of the tissue sections indicates there is clearly a pattern in the spatial structure. Different projections of the spatial structure of the melanoma are obtained by the different measurement methods. The spectral clustering on the data was utilized to describe the structure in the data. According to the clustering results, there are distinct clusters of observations in the histological data. The spatial elemental distribution of the metals Cu and Zn cannot be clustered -the data form one compact cluster. The clustering of the histological images produces clusters which are related to the annotation of the biological samples in broader terms -the differences between fibrous and cancerous tissue.
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