Nonalcoholic Fatty Pancreas Disease: Clinical Consequences

J 2020

Nonalcoholic Fatty Pancreas Disease: Clinical Consequences

DITE, Petr, Martin BLAHO, Martina BOJKOVA, Petr JABANDŽIEV, Lumír KUNOVSKÝ et. al.

Základní údaje

Originální název

Nonalcoholic Fatty Pancreas Disease: Clinical Consequences

Autoři

DITE, Petr (203 Česká republika), Martin BLAHO (203 Česká republika), Martina BOJKOVA (203 Česká republika), Petr JABANDŽIEV (203 Česká republika, domácí) a Lumír KUNOVSKÝ (203 Česká republika, garant, domácí)

Vydání

Digestive Diseases, BASEL, KARGER, 2020, 0257-2753

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30219 Gastroenterology and hepatology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.404

Kód RIV

RIV/00216224:14110/20:00115602

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1159/000505366

UT WoS

000522852200011

Klíčová slova anglicky

Pancreas steatosis; Nonalcoholic fatty pancreas disease; Nonalcoholic steatopancreatitis; Metabolic syndrome; Cardiovascular diseases; Diabetes mellitus; Obesity; Pancreatic carcinoma; Exocrine pancreatic insufficiency

Štítky

14110213, 14110223, 14110317, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 5. 2020 09:02, Mgr. Tereza Miškechová

Anotace

V originále

Metabolic syndrome and its components such as obesity, hypertriglyceridemia, type-2 diabetes mellitus (DM-T2), and arterial hypertension are unequivocally serious problems for every society. This is especially true in economically developed countries where the imbalance in lifestyle between caloric intake and caloric output still gets greater and greater. This fact is not only a concern for the adult population but for children as well. However, metabolic syndrome does not only affect society and health in regards to cardiovascular diseases, it significantly concerns gastroenterology where it is classified as nonalcoholic fatty pancreas disease (NAFPD). The data gained from several trials show that the prevalence of NAFDP is 33% (95% CI 24-41%). When it comes to the diagnostic procedures concerning the presence of pancreatic fat, a whole spectrum of suitable methods are recommended. Probably, the most exact method is the use of magnetic resonance imaging. However, for common clinical practice, the abdominal sonographic examination based on the comparison of the pancreatic parenchymatous echogenity versus renal or hepatic echogenity is used. The clinical consequences of pancreatic steatosis and steatopancreatitis are significant. These diseases are connected with DM-T2 and insulin resistance. In recent years, changes of exocrine pancreatic function, particularly its decrease, have also been described. It is known that there is a close correlation between NAFPD and nonalcoholic hepatic steatosis and also with the increased thickness of aortic intima-media. There is also an important relationship between NAFPD and pancreatic carcinoma. Pancreatic steatosis, and especially its NAFPD form, is a serious state which can be treatable by the possible effective management of metabolic syndrome parameters, including obesity.

Citovat

DITE, Petr, Martin BLAHO, Martina BOJKOVA, Petr JABANDŽIEV a Lumír KUNOVSKÝ. Nonalcoholic Fatty Pancreas Disease: Clinical Consequences. Digestive Diseases. BASEL: KARGER, 2020, roč. 38, č. 2, s. 143-149. ISSN 0257-2753. Dostupné z: https://dx.doi.org/10.1159/000505366.

@article{1652956,
   author = {Dite, Petr and Blaho, Martin and Bojkova, Martina and Jabandžiev, Petr and Kunovský, Lumír},
   article_location = {BASEL},
   article_number = {2},
   doi = {http://dx.doi.org/10.1159/000505366},
   keywords = {Pancreas steatosis; Nonalcoholic fatty pancreas disease; Nonalcoholic steatopancreatitis; Metabolic syndrome; Cardiovascular diseases; Diabetes mellitus; Obesity; Pancreatic carcinoma; Exocrine pancreatic insufficiency},
   language = {eng},
   issn = {0257-2753},
   journal = {Digestive Diseases},
   title = {Nonalcoholic Fatty Pancreas Disease: Clinical Consequences},
   url = {https://www.karger.com/Article/FullText/505366},
   volume = {38},
   year = {2020}
}

TY  - JOUR
ID  - 1652956
AU  - Dite, Petr - Blaho, Martin - Bojkova, Martina - Jabandžiev, Petr - Kunovský, Lumír
PY  - 2020
TI  - Nonalcoholic Fatty Pancreas Disease: Clinical Consequences
JF  - Digestive Diseases
VL  - 38
IS  - 2
SP  - 143-149
EP  - 143-149
PB  - KARGER
SN  - 02572753
KW  - Pancreas steatosis
KW  - Nonalcoholic fatty pancreas disease
KW  - Nonalcoholic steatopancreatitis
KW  - Metabolic syndrome
KW  - Cardiovascular diseases
KW  - Diabetes mellitus
KW  - Obesity
KW  - Pancreatic carcinoma
KW  - Exocrine pancreatic insufficiency
UR  - https://www.karger.com/Article/FullText/505366
L2  - https://www.karger.com/Article/FullText/505366
N2  - Metabolic syndrome and its components such as obesity, hypertriglyceridemia, type-2 diabetes mellitus (DM-T2), and arterial hypertension are unequivocally serious problems for every society. This is especially true in economically developed countries where the imbalance in lifestyle between caloric intake and caloric output still gets greater and greater. This fact is not only a concern for the adult population but for children as well. However, metabolic syndrome does not only affect society and health in regards to cardiovascular diseases, it significantly concerns gastroenterology where it is classified as nonalcoholic fatty pancreas disease (NAFPD). The data gained from several trials show that the prevalence of NAFDP is 33% (95% CI 24-41%). When it comes to the diagnostic procedures concerning the presence of pancreatic fat, a whole spectrum of suitable methods are recommended. Probably, the most exact method is the use of magnetic resonance imaging. However, for common clinical practice, the abdominal sonographic examination based on the comparison of the pancreatic parenchymatous echogenity versus renal or hepatic echogenity is used. The clinical consequences of pancreatic steatosis and steatopancreatitis are significant. These diseases are connected with DM-T2 and insulin resistance. In recent years, changes of exocrine pancreatic function, particularly its decrease, have also been described. It is known that there is a close correlation between NAFPD and nonalcoholic hepatic steatosis and also with the increased thickness of aortic intima-media. There is also an important relationship between NAFPD and pancreatic carcinoma. Pancreatic steatosis, and especially its NAFPD form, is a serious state which can be treatable by the possible effective management of metabolic syndrome parameters, including obesity.
ER  -

DITE, Petr, Martin BLAHO, Martina BOJKOVA, Petr JABANDŽIEV a Lumír KUNOVSKÝ. Nonalcoholic Fatty Pancreas Disease: Clinical Consequences. \textit{Digestive Diseases}. BASEL: KARGER, 2020, roč.~38, č.~2, s.~143-149. ISSN~0257-2753. Dostupné z: https://dx.doi.org/10.1159/000505366.

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