Endoscopic recurrence after ileocaecal resection for Crohn's
disease relating to microscopic inflammation at resection
margins

a 2020

Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins

KUNOVSKÝ, Lumír, Karolina POREDSKÁ, Filip MAREK, Zdeněk KALA, Vladimír PROCHÁZKA et. al.

Základní údaje

Originální název

Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins

Autoři

Vydání

ESGE Days 2020, 2020

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30219 Gastroenterology and hepatology

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1055/s-0040-1704693

Klíčová slova anglicky

Crohn's disease; ileocaecal resection; resection margins

Změněno: 8. 4. 2021 08:42, Mgr. Tereza Miškechová

Anotace

V originále

Aims An early postoperative endoscopic recurrence of Crohn´s disease after ileocaecal resection remains unclear concerning its pathogenesis and risk factors. In our study, we evaluated the influence of histological inflammation at the resection margins on endoscopic recurrence. Methods Patients with CD who underwent ileocaecal resection have been prospectively followed up in our study. The specimens were histologically analysed for inflammation at both of the resection margins (ileal and colonic). We evaluated whether histological results of the resection margins are correlated with endoscopic recurrence of CD based on colonoscopy 6 months after ileocaecal resection. Results We have included 107 patients in our study. Six months after ileocaecal resection, 23 patients (21.5 %) had an endoscopic recurrence of CD. The histological signs of CD at the resection margins were associated with a higher endoscopic recurrence (56.5 % versus 4.8 %, p < 0.001). Conclusions Microscopic inflammation at the resection margins was significantly associated with a higher risk of early postoperative endoscopic recurrence after an ileocaecal resection for CD.

Citovat

KUNOVSKÝ, Lumír, Karolina POREDSKÁ, Filip MAREK, Zdeněk KALA, Vladimír PROCHÁZKA, Jiří DOLINA, Vladimír ZBOŘIL, Radek KROUPA, Jitka VACULOVÁ, Tomáš PAVLÍK, Jakub VLAŽNÝ, Petr JABANDŽIEV, Dominika IVANECKÁ a Ladislav MITÁŠ. Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins. In ESGE Days 2020. 2020. Dostupné z: https://dx.doi.org/10.1055/s-0040-1704693.

@proceedings{1653436,
   author = {Kunovský, Lumír and Poredská, Karolina and Marek, Filip and Kala, Zdeněk and Procházka, Vladimír and Dolina, Jiří and Zbořil, Vladimír and Kroupa, Radek and Vaculová, Jitka and Pavlík, Tomáš and Vlažný, Jakub and Jabandžiev, Petr and Ivanecká, Dominika and Mitáš, Ladislav},
   booktitle = {ESGE Days 2020},
   doi = {http://dx.doi.org/10.1055/s-0040-1704693},
   keywords = {Crohn's disease; ileocaecal resection; resection margins},
   language = {eng},
   title = {Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins},
   url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1704693},
   year = {2020}
}

TY  - CONF
ID  - 1653436
AU  - Kunovský, Lumír - Poredská, Karolina - Marek, Filip - Kala, Zdeněk - Procházka, Vladimír - Dolina, Jiří - Zbořil, Vladimír - Kroupa, Radek - Vaculová, Jitka - Pavlík, Tomáš - Vlažný, Jakub - Jabandžiev, Petr - Ivanecká, Dominika - Mitáš, Ladislav
PY  - 2020
TI  - Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins
KW  - Crohn's disease
KW  - ileocaecal resection
KW  - resection margins
UR  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1704693
L2  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1704693
N2  - Aims An early postoperative endoscopic recurrence of Crohn´s disease after ileocaecal resection remains unclear concerning its pathogenesis and risk factors. In our study, we evaluated the influence of histological inflammation at the resection margins on endoscopic recurrence. Methods Patients with CD who underwent ileocaecal resection have been prospectively followed up in our study. The specimens were histologically analysed for inflammation at both of the resection margins (ileal and colonic). We evaluated whether histological results of the resection margins are correlated with endoscopic recurrence of CD based on colonoscopy 6 months after ileocaecal resection. Results We have included 107 patients in our study. Six months after ileocaecal resection, 23 patients (21.5 %) had an endoscopic recurrence of CD. The histological signs of CD at the resection margins were associated with a higher endoscopic recurrence (56.5 % versus 4.8 %, p < 0.001). Conclusions Microscopic inflammation at the resection margins was significantly associated with a higher risk of early postoperative endoscopic recurrence after an ileocaecal resection for CD.
ER  -

KUNOVSKÝ, Lumír, Karolina POREDSKÁ, Filip MAREK, Zdeněk KALA, Vladimír PROCHÁZKA, Jiří DOLINA, Vladimír ZBOŘIL, Radek KROUPA, Jitka VACULOVÁ, Tomáš PAVLÍK, Jakub VLAŽNÝ, Petr JABANDŽIEV, Dominika IVANECKÁ a Ladislav MITÁŠ. Endoscopic recurrence after ileocaecal resection for Crohn's disease relating to microscopic inflammation at resection margins. In \textit{ESGE Days 2020}. 2020. Dostupné z: https://dx.doi.org/10.1055/s-0040-1704693.

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