Mussel-mimicking sulfobetaine-based copolymer with metal
tunable gelation, self-healing and antibacterial capability

J 2020

Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability

MRLIK, M., Mário ŠPÍREK, J. AL-KHORI, A. A. AHMAD, J. MOSNACEK et. al.

Základní údaje

Originální název

Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability

Autoři

MRLIK, M. (203 Česká republika, garant), Mário ŠPÍREK (703 Slovensko, domácí), J. AL-KHORI (634 Katar), A. A. AHMAD (634 Katar), J. MOSNACEK (703 Slovensko), M. A. ALMAADEED (634 Katar) a P. KASAK (634 Katar)

Vydání

Arabian Journal of Chemistry, Amsterdam, ELSEVIER, 2020, 1878-5352

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10404 Polymer science

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 5.165

Kód RIV

RIV/00216224:14110/20:00115979

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.arabjc.2017.03.009

UT WoS

000505076000018

Klíčová slova anglicky

Polysulfobetaine; Metal coordination; Antibacterial; Self-healing; Hydrogels; Catecholamine polymers

Štítky

14110513, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 7. 2020 08:23, Mgr. Tereza Miškechová

Anotace

V originále

In the present study, the sulfobetaine-based copolymer bearing a dopamine functionality showed gel formation adjusted by the application of metal salts for gelation and various values of pH. Normally, the liquid-like solution of the sulfobetaine-based copolymer and metal cross-linkers is transformed to a gel-like state upon increasing the pH values in the presence of Fe3+ and Ti3+. Metal-induced coordination is reversible by means of the application of EDTA as a chelating agent. In the case of Ag+ ions, the gel is formed through a redox process accompanied with the oxidative coupling of the dopamine moieties and Ag-0 particle formation. Mussel-mimicking and metal-dependent viscoelastic properties were observed for Fe3+, Ti3+, and Ag+ cross-linking agents, with additionally enhanced self-healing behavior in comparison with the covalently cross-linked IO4- analogues. Antibacterial properties can be achieved both in solution and on the surface using the proper concentration of Ag+ ions used for gelation; thus, a tunable amount of the Ag-0 particles are formed in the hydrogel. The cytotoxicity was elucidated by the both MTT assay on the NIH/3T3 fibroblast cell line and direct contact method using human dermal fibroblast cell (F121) and shows the non-toxic character of the synthesized copolymer. (C) 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.

Citovat

MRLIK, M., Mário ŠPÍREK, J. AL-KHORI, A. A. AHMAD, J. MOSNACEK, M. A. ALMAADEED a P. KASAK. Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability. Arabian Journal of Chemistry. Amsterdam: ELSEVIER, 2020, roč. 13, č. 1, s. 193-204. ISSN 1878-5352. Dostupné z: https://dx.doi.org/10.1016/j.arabjc.2017.03.009.

@article{1670344,
   author = {Mrlik, M. and Špírek, Mário and AlandKhori, J. and Ahmad, A. A. and Mosnacek, J. and AlMaadeed, M. A. and Kasak, P.},
   article_location = {Amsterdam},
   article_number = {1},
   doi = {http://dx.doi.org/10.1016/j.arabjc.2017.03.009},
   keywords = {Polysulfobetaine; Metal coordination; Antibacterial; Self-healing; Hydrogels; Catecholamine polymers},
   language = {eng},
   issn = {1878-5352},
   journal = {Arabian Journal of Chemistry},
   title = {Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability},
   url = {https://www.sciencedirect.com/science/article/pii/S1878535217300679?via%3Dihub},
   volume = {13},
   year = {2020}
}

TY  - JOUR
ID  - 1670344
AU  - Mrlik, M. - Špírek, Mário - Al-Khori, J. - Ahmad, A. A. - Mosnacek, J. - AlMaadeed, M. A. - Kasak, P.
PY  - 2020
TI  - Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability
JF  - Arabian Journal of Chemistry
VL  - 13
IS  - 1
SP  - 193-204
EP  - 193-204
PB  - ELSEVIER
SN  - 18785352
KW  - Polysulfobetaine
KW  - Metal coordination
KW  - Antibacterial
KW  - Self-healing
KW  - Hydrogels
KW  - Catecholamine polymers
UR  - https://www.sciencedirect.com/science/article/pii/S1878535217300679?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S1878535217300679?via%3Dihub
N2  - In the present study, the sulfobetaine-based copolymer bearing a dopamine functionality showed gel formation adjusted by the application of metal salts for gelation and various values of pH. Normally, the liquid-like solution of the sulfobetaine-based copolymer and metal cross-linkers is transformed to a gel-like state upon increasing the pH values in the presence of Fe3+ and Ti3+. Metal-induced coordination is reversible by means of the application of EDTA as a chelating agent. In the case of Ag+ ions, the gel is formed through a redox process accompanied with the oxidative coupling of the dopamine moieties and Ag-0 particle formation. Mussel-mimicking and metal-dependent viscoelastic properties were observed for Fe3+, Ti3+, and Ag+ cross-linking agents, with additionally enhanced self-healing behavior in comparison with the covalently cross-linked IO4- analogues. Antibacterial properties can be achieved both in solution and on the surface using the proper concentration of Ag+ ions used for gelation; thus, a tunable amount of the Ag-0 particles are formed in the hydrogel. The cytotoxicity was elucidated by the both MTT assay on the NIH/3T3 fibroblast cell line and direct contact method using human dermal fibroblast cell (F121) and shows the non-toxic character of the synthesized copolymer. (C) 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.
ER  -

MRLIK, M., Mário ŠPÍREK, J. AL-KHORI, A. A. AHMAD, J. MOSNACEK, M. A. ALMAADEED a P. KASAK. Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability. \textit{Arabian Journal of Chemistry}. Amsterdam: ELSEVIER, 2020, roč.~13, č.~1, s.~193-204. ISSN~1878-5352. Dostupné z: https://dx.doi.org/10.1016/j.arabjc.2017.03.009.

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