2020
Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention
LISKOVA, A., P. STEFANICKA, M. SAMEC, Karel ŠMEJKAL, P. ZUBOR et. al.Základní údaje
Originální název
Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention
Autoři
LISKOVA, A. (703 Slovensko), P. STEFANICKA (703 Slovensko), M. SAMEC (703 Slovensko), Karel ŠMEJKAL (203 Česká republika, domácí), P. ZUBOR (703 Slovensko), T. BIELIK (703 Slovensko), K. BISKUPSKA-BODOVA (703 Slovensko), T. K. KWON (410 Korejská republika), J. DANKO (703 Slovensko), D. BUSSELBERG (634 Katar), M. ADAMEK (616 Polsko), L. RODRIGO (724 Španělsko), Peter KRUŽLIAK (703 Slovensko, garant, domácí), A. SHLEIKIN (643 Rusko) a P. KUBATKA (703 Slovensko)
Vydání
Clinical and Experimental Medicine, Milan, SPRINGER-VERLAG ITALIA SRL, 2020, 1591-8890
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30308 Nutrition, Dietetics
Stát vydavatele
Itálie
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 3.984
Kód RIV
RIV/00216224:14110/20:00115989
Organizační jednotka
Lékařská fakulta
UT WoS
000518152000001
Klíčová slova anglicky
Carcinogens; Dietary phytochemicals; Antioxidant; Scavenging effect; Detoxification; Metabolic activation; Chemoprevention
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 4. 5. 2021 13:03, Mgr. Tereza Miškechová
Anotace
V originále
Health-threatening consequences of carcinogen exposure are mediated via occurrence of electrophiles or reactive oxygen species. As a result, the accumulation of biomolecular damage leads to the cancer initiation, promotion or progression. Accordingly, there is an association between lifestyle factors including inappropriate diet or carcinogen formation during food processing, mainstream, second or third-hand tobacco smoke and other environmental or occupational carcinogens and malignant transformation. Nevertheless, increasing evidence supports the protective effects of naturally occurring phytochemicals against carcinogen exposure as well as carcinogenesis in general. Isolated phytochemicals or their mixtures present in the whole plant food demonstrate efficacy against malignancy induced by carcinogens widely spread in our environment. Phytochemicals also minimize the generation of carcinogenic substances during the processing of meat and meat products. Based on numerous data, selected phytochemicals or plant foods should be highly recommended to become a stable and regular part of the diet as the protectors against carcinogenesis.