J 2020

Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention

LISKOVA, A., P. STEFANICKA, M. SAMEC, Karel ŠMEJKAL, P. ZUBOR et. al.

Základní údaje

Originální název

Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention

Autoři

LISKOVA, A. (703 Slovensko), P. STEFANICKA (703 Slovensko), M. SAMEC (703 Slovensko), Karel ŠMEJKAL (203 Česká republika, domácí), P. ZUBOR (703 Slovensko), T. BIELIK (703 Slovensko), K. BISKUPSKA-BODOVA (703 Slovensko), T. K. KWON (410 Korejská republika), J. DANKO (703 Slovensko), D. BUSSELBERG (634 Katar), M. ADAMEK (616 Polsko), L. RODRIGO (724 Španělsko), Peter KRUŽLIAK (703 Slovensko, garant, domácí), A. SHLEIKIN (643 Rusko) a P. KUBATKA (703 Slovensko)

Vydání

Clinical and Experimental Medicine, Milan, SPRINGER-VERLAG ITALIA SRL, 2020, 1591-8890

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30308 Nutrition, Dietetics

Stát vydavatele

Itálie

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 3.984

Kód RIV

RIV/00216224:14110/20:00115989

Organizační jednotka

Lékařská fakulta

UT WoS

000518152000001

Klíčová slova anglicky

Carcinogens; Dietary phytochemicals; Antioxidant; Scavenging effect; Detoxification; Metabolic activation; Chemoprevention

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 4. 5. 2021 13:03, Mgr. Tereza Miškechová

Anotace

V originále

Health-threatening consequences of carcinogen exposure are mediated via occurrence of electrophiles or reactive oxygen species. As a result, the accumulation of biomolecular damage leads to the cancer initiation, promotion or progression. Accordingly, there is an association between lifestyle factors including inappropriate diet or carcinogen formation during food processing, mainstream, second or third-hand tobacco smoke and other environmental or occupational carcinogens and malignant transformation. Nevertheless, increasing evidence supports the protective effects of naturally occurring phytochemicals against carcinogen exposure as well as carcinogenesis in general. Isolated phytochemicals or their mixtures present in the whole plant food demonstrate efficacy against malignancy induced by carcinogens widely spread in our environment. Phytochemicals also minimize the generation of carcinogenic substances during the processing of meat and meat products. Based on numerous data, selected phytochemicals or plant foods should be highly recommended to become a stable and regular part of the diet as the protectors against carcinogenesis.