| KACEROVSKY, Marian, Lenka PLISKOVA, Radka BOLEHOVSKA, Romana GERYCHOVÁ, Petr JANKŮ, Petr MATLAK, Ondrej SIMETKA, Tomas FAIST, Jan MLS, Petr VESCICIK, Helena ZEMLICKOVA, Bo JACOBSSON a Ivana MUSILOVA. Lactobacilli-dominated cervical microbiota in women with preterm prelabor rupture of membranes. Pediatric Research. New York: Nature Publishing Group, 2020, roč. 87, č. 5, s. 952-960. ISSN 0031-3998. Dostupné z: https://dx.doi.org/10.1038/s41390-019-0692-1. |
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@article{1670597,
author = {Kacerovsky, Marian and Pliskova, Lenka and Bolehovska, Radka and Gerychová, Romana and Janků, Petr and Matlak, Petr and Simetka, Ondrej and Faist, Tomas and Mls, Jan and Vescicik, Petr and Zemlickova, Helena and Jacobsson, Bo and Musilova, Ivana},
article_location = {New York},
article_number = {5},
doi = {http://dx.doi.org/10.1038/s41390-019-0692-1},
keywords = {INTRAAMNIOTIC INFLAMMATION; PREMATURE RUPTURE; AMNIOTIC CAVITY; INTERLEUKIN-6; INVASION; FLUID},
language = {eng},
issn = {0031-3998},
journal = {Pediatric Research},
title = {Lactobacilli-dominated cervical microbiota in women with preterm prelabor rupture of membranes},
url = {https://www.nature.com/articles/s41390-019-0692-1},
volume = {87},
year = {2020}
}
TY - JOUR
ID - 1670597
AU - Kacerovsky, Marian - Pliskova, Lenka - Bolehovska, Radka - Gerychová, Romana - Janků, Petr - Matlak, Petr - Simetka, Ondrej - Faist, Tomas - Mls, Jan - Vescicik, Petr - Zemlickova, Helena - Jacobsson, Bo - Musilova, Ivana
PY - 2020
TI - Lactobacilli-dominated cervical microbiota in women with preterm prelabor rupture of membranes
JF - Pediatric Research
VL - 87
IS - 5
SP - 952-960
EP - 952-960
PB - Nature Publishing Group
SN - 00313998
KW - INTRAAMNIOTIC INFLAMMATION
KW - PREMATURE RUPTURE
KW - AMNIOTIC CAVITY
KW - INTERLEUKIN-6
KW - INVASION
KW - FLUID
UR - https://www.nature.com/articles/s41390-019-0692-1
L2 - https://www.nature.com/articles/s41390-019-0692-1
N2 - Background To determine the association between microbial invasion of the amniotic cavity (MIAC) and the presence of Lactobacillus crispatus- or Lactobacillus iners-dominated cervical microbiota in pregnancies with preterm prelabor rupture of membrane. Next, to assess the relationship between the presence of L. crispatus- or L. iners-dominated cervical microbiota and short-term neonatal morbidity. Method A total of 311 women were included. Cervical samples were obtained using a Dacron polyester swab and amniotic fluid samples were obtained by transabdominal amniocentesis. Bacterial DNA, L. crispatus, and L. iners in the cervical samples were assessed by PCR. Cervical microbiota was assigned as L. crispatus- or L. iners-dominated when the relative abundance of L. crispatus or L. iners was >= 50% of the whole cervical microbiota, respectively. Results Women with MIAC showed a lower rate of L. crispatus-dominated cervical microbiota (21% vs. 39%; p = 0.003) than those without MIAC. Lactobacillus crispatus-dominated cervical microbiota was associated with a lower rate of early-onset sepsis (0% vs. 5%; p = 0.02). Conclusions The presence of L. crispatus-dominated cervical microbiota in women with preterm prelabor rupture of membrane was associated with a lower risk of intra-amniotic complications and subsequent development of early-onset sepsis of newborns.
ER -
KACEROVSKY, Marian, Lenka PLISKOVA, Radka BOLEHOVSKA, Romana GERYCHOVÁ, Petr JANKŮ, Petr MATLAK, Ondrej SIMETKA, Tomas FAIST, Jan MLS, Petr VESCICIK, Helena ZEMLICKOVA, Bo JACOBSSON a Ivana MUSILOVA. Lactobacilli-dominated cervical microbiota in women with preterm prelabor rupture of membranes. \textit{Pediatric Research}. New York: Nature Publishing Group, 2020, roč.~87, č.~5, s.~952-960. ISSN~0031-3998. Dostupné z: https://dx.doi.org/10.1038/s41390-019-0692-1.
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