Heart rate as an independent predictor of long term mortality
of acute heart failure patients in sinus rhythm according to
their ejection fraction: data from the AHEAD registry

J 2020

Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry

JARKOVSKÝ, Jiří, Jindřich ŠPINAR, Benoit TYL, Francoise FOUGEROUSSE, Jiří VÍTOVEC et. al.

Základní údaje

Originální název

Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry

Autoři

JARKOVSKÝ, Jiří (203 Česká republika, domácí), Jindřich ŠPINAR (203 Česká republika, domácí), Benoit TYL (250 Francie), Francoise FOUGEROUSSE (250 Francie), Jiří VÍTOVEC (203 Česká republika, domácí), Ales LINHART (203 Česká republika), Petr WIDIMSKY (203 Česká republika), Roman MIKLÍK (203 Česká republika), Lenka ŠPINAROVÁ (203 Česká republika, domácí), Jan BELOHLAVEK (203 Česká republika), Filip MALEK (203 Česká republika), Marián FELŠŐCI (703 Slovensko, domácí), Jiri KETTNER (203 Česká republika), Petr OSTADAL (203 Česká republika), Jan VACLAVIK (203 Česká republika), Ladislav DUŠEK (203 Česká republika, domácí), Petr LOKAJ (203 Česká republika, domácí), Alexandre MEBAZAA (250 Francie), Alain Cohen SOLAL (250 Francie) a Jiří PAŘENICA (203 Česká republika, domácí)

Vydání

European Journal of Internal Medicine, AMSTERDAM, ELSEVIER, 2020, 0953-6205

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30218 General and internal medicine

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.487

Kód RIV

RIV/00216224:14110/20:00116142

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.ejim.2020.04.022

UT WoS

000553841300018

Klíčová slova anglicky

Acute heart failure; AHEAD; Prognosis; Sinus rhythm; Heart rate; Preserved ejection fraction

Štítky

14110115, 14110211, 14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 8. 2020 09:37, Mgr. Tereza Miškechová

Anotace

V originále

Background: Heart rate (HR) at admission in patients with acute heart failure (AHF) has been shown to be an important risk marker of in-hospital mortality. However, its relation with mid and long-term prognosis as well as the impact of Ejection Fraction (EF) is unknown. Our objective was to study the relationship between long-term survival and HR at admission depending on EF in a cohort of patients hospitalized for AHF. Methods: We analyzed the data of 2335 patients in sinus rhythm hospitalized for AHF from AHEAD registry. Patients with cardiogenic shock and AHF from surgical or non-cardiac etiology were excluded. Results: Survival rates at 6 and 12 months were 84.8% and 78% respectively. Increased age, decreased diastolic BP, lack of PCI during hospitalization, increased creatinine level and increased HR (with different cut-offs according to EF categories) were found as predictors whatever the EF at 6 and 12 months. Optimal prognostic cut-offs of heart rate were identified for Heart Failure with reduced EF at 100 bpm, for Heart Failure with mid-range EF at 90 bpm and for Heart Failure with preserved EF at 80 bpm for both 6 and 12 months. Conclusion: Our study suggests that HR at admission appears to be an independent prognostic parameter in AHF patients in sinus rhythm irrespective of EF and can be used to classify patients according to the severity of the disease.

Citovat

JARKOVSKÝ, Jiří, Jindřich ŠPINAR, Benoit TYL, Francoise FOUGEROUSSE, Jiří VÍTOVEC, Ales LINHART, Petr WIDIMSKY, Roman MIKLÍK, Lenka ŠPINAROVÁ, Jan BELOHLAVEK, Filip MALEK, Marián FELŠŐCI, Jiri KETTNER, Petr OSTADAL, Jan VACLAVIK, Ladislav DUŠEK, Petr LOKAJ, Alexandre MEBAZAA, Alain Cohen SOLAL a Jiří PAŘENICA. Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry. European Journal of Internal Medicine. AMSTERDAM: ELSEVIER, 2020, roč. 78, AUG 2020, s. 88-94. ISSN 0953-6205. Dostupné z: https://dx.doi.org/10.1016/j.ejim.2020.04.022.

@article{1673238,
   author = {Jarkovský, Jiří and Špinar, Jindřich and Tyl, Benoit and Fougerousse, Francoise and Vítovec, Jiří and Linhart, Ales and Widimsky, Petr and Miklík, Roman and Špinarová, Lenka and Belohlavek, Jan and Malek, Filip and Felšőci, Marián and Kettner, Jiri and Ostadal, Petr and Vaclavik, Jan and Dušek, Ladislav and Lokaj, Petr and Mebazaa, Alexandre and Solal, Alain Cohen and Pařenica, Jiří},
   article_location = {AMSTERDAM},
   article_number = {AUG 2020},
   doi = {http://dx.doi.org/10.1016/j.ejim.2020.04.022},
   keywords = {Acute heart failure; AHEAD; Prognosis; Sinus rhythm; Heart rate; Preserved ejection fraction},
   language = {eng},
   issn = {0953-6205},
   journal = {European Journal of Internal Medicine},
   title = {Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry},
   url = {https://www.sciencedirect.com/science/article/pii/S0953620520301369?via%3Dihub},
   volume = {78},
   year = {2020}
}

TY  - JOUR
ID  - 1673238
AU  - Jarkovský, Jiří - Špinar, Jindřich - Tyl, Benoit - Fougerousse, Francoise - Vítovec, Jiří - Linhart, Ales - Widimsky, Petr - Miklík, Roman - Špinarová, Lenka - Belohlavek, Jan - Malek, Filip - Felšőci, Marián - Kettner, Jiri - Ostadal, Petr - Vaclavik, Jan - Dušek, Ladislav - Lokaj, Petr - Mebazaa, Alexandre - Solal, Alain Cohen - Pařenica, Jiří
PY  - 2020
TI  - Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry
JF  - European Journal of Internal Medicine
VL  - 78
IS  - AUG 2020
SP  - 88-94
EP  - 88-94
PB  - ELSEVIER
SN  - 09536205
KW  - Acute heart failure
KW  - AHEAD
KW  - Prognosis
KW  - Sinus rhythm
KW  - Heart rate
KW  - Preserved ejection fraction
UR  - https://www.sciencedirect.com/science/article/pii/S0953620520301369?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S0953620520301369?via%3Dihub
N2  - Background: Heart rate (HR) at admission in patients with acute heart failure (AHF) has been shown to be an important risk marker of in-hospital mortality. However, its relation with mid and long-term prognosis as well as the impact of Ejection Fraction (EF) is unknown. Our objective was to study the relationship between long-term survival and HR at admission depending on EF in a cohort of patients hospitalized for AHF. Methods: We analyzed the data of 2335 patients in sinus rhythm hospitalized for AHF from AHEAD registry. Patients with cardiogenic shock and AHF from surgical or non-cardiac etiology were excluded. Results: Survival rates at 6 and 12 months were 84.8% and 78% respectively. Increased age, decreased diastolic BP, lack of PCI during hospitalization, increased creatinine level and increased HR (with different cut-offs according to EF categories) were found as predictors whatever the EF at 6 and 12 months. Optimal prognostic cut-offs of heart rate were identified for Heart Failure with reduced EF at 100 bpm, for Heart Failure with mid-range EF at 90 bpm and for Heart Failure with preserved EF at 80 bpm for both 6 and 12 months. Conclusion: Our study suggests that HR at admission appears to be an independent prognostic parameter in AHF patients in sinus rhythm irrespective of EF and can be used to classify patients according to the severity of the disease.
ER  -

JARKOVSKÝ, Jiří, Jindřich ŠPINAR, Benoit TYL, Francoise FOUGEROUSSE, Jiří VÍTOVEC, Ales LINHART, Petr WIDIMSKY, Roman MIKLÍK, Lenka ŠPINAROVÁ, Jan BELOHLAVEK, Filip MALEK, Marián FELŠ$\backslash$H OCI, Jiri KETTNER, Petr OSTADAL, Jan VACLAVIK, Ladislav DUŠEK, Petr LOKAJ, Alexandre MEBAZAA, Alain Cohen SOLAL a Jiří PAŘENICA. Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry. \textit{European Journal of Internal Medicine}. AMSTERDAM: ELSEVIER, 2020, roč.~78, AUG 2020, s.~88-94. ISSN~0953-6205. Dostupné z: https://dx.doi.org/10.1016/j.ejim.2020.04.022.

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