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@article{1679495,
author = {Vargová, Lenka and Horáčková, Ladislava and Vymazalová, Kateřina and Němečková, Alena and Tvrdý, Zdeněk and Galuška, Luděk and Mitáček, Jiří and Fialová, Dana},
article_location = {New York},
article_number = {DEC 2020},
doi = {http://dx.doi.org/10.1016/j.ijpp.2020.09.001},
keywords = {Lower jaw; Early Middle Ages; Inflammation; Mycoses; Czech Republic},
language = {eng},
issn = {1879-9817},
journal = {International Journal of Paleopathology},
title = {A very rare case of possible actinomycosis of the mandible from the Middle Ages},
url = {https://www.sciencedirect.com/science/article/pii/S1879981720300462?via%3Dihub},
volume = {31},
year = {2020}
}
TY - JOUR
ID - 1679495
AU - Vargová, Lenka - Horáčková, Ladislava - Vymazalová, Kateřina - Němečková, Alena - Tvrdý, Zdeněk - Galuška, Luděk - Mitáček, Jiří - Fialová, Dana
PY - 2020
TI - A very rare case of possible actinomycosis of the mandible from the Middle Ages
JF - International Journal of Paleopathology
VL - 31
IS - DEC 2020
SP - 53-59
EP - 53-59
PB - Elsevier
SN - 18799817
KW - Lower jaw
KW - Early Middle Ages
KW - Inflammation
KW - Mycoses
KW - Czech Republic
UR - https://www.sciencedirect.com/science/article/pii/S1879981720300462?via%3Dihub
L2 - https://www.sciencedirect.com/science/article/pii/S1879981720300462?via%3Dihub
N2 - Objective Documented cases of actinomycosis in archaeological skeletons are very rare, especially from Central Europe. Our contribution will help facilitate the differential diagnosis of this disease for other paleopathologists. Material This paper describes a pathological finding of the skeleton of a 40-year-old male from a burial ground in Sady-Špitálky (Czech Republic) dated to the 10th-12th century. Methods The affected skeleton was evaluated as a probable case of actinomycosis on the basis of a detailed macroscopic, X-ray and histological examination. The osteolytic foci examined were compared with similar changes caused by tuberculosis, syphilis and mycoses. Results The character and location of the defect on the mandible is indicative of organ actinomycosis and is also reflected by the lytic lesion observed on a lumbar vertebra. Conclusions The described case can be considered one of the very rare paleopathological findings of possible actinomycosis in humans in Central Europe. Significance Good evidence of bone actinomycosis findings may be beneficial for further paleopathological and epidemiological studies, especially for research focused on the diachronic development of actinomycosis in Europe. In doing so, all available factors, such as hygiene habits, nutrition, social structure and overall health of the population that could be causally related to its origin, course and treatment, can be taken into account. Limitations The mandible of the studied individual was damaged, especially in the area affected by the lesion, so the paleopathological analysis was difficult to perform. Suggestion for the future research In future, actinomycosis in this skeleton may be confirmed by bio-molecular analysis.
ER -
VARGOVÁ, Lenka, Ladislava HORÁČKOVÁ, Kateřina VYMAZALOVÁ, Alena NĚMEČKOVÁ, Zdeněk TVRDÝ, Luděk GALUŠKA, Jiří MITÁČEK a Dana FIALOVÁ. A very rare case of possible actinomycosis of the mandible from the Middle Ages. \textit{International Journal of Paleopathology}. New York: Elsevier, 2020, roč.~31, DEC 2020, s.~53-59. ISSN~1879-9817. Dostupné z: https://dx.doi.org/10.1016/j.ijpp.2020.09.001.
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