Utility of Time-Variant Multiphase CTA Color Maps in Outcome
Prediction for Acute Ischemic Stroke Due to Anterior
Circulation Large Vessel Occlusion

J 2021

Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion

OSPEL, Johanna M., Petra CIMFLOVÁ, Ondřej VOLNÝ, Wu QIU, Moiz HAFEEZ et. al.

Basic information

Original name

Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion

Authors

OSPEL, Johanna M. (756 Switzerland), Petra CIMFLOVÁ (203 Czech Republic, belonging to the institution), Ondřej VOLNÝ (203 Czech Republic, belonging to the institution), Wu QIU, Moiz HAFEEZ, Arnuv MAYANK, Mohamed NAJM, Kevin CHUNG, Nima KASHANI, Mohammed A. ALMEKHLAFI, Bijoy K. MENON and Mayank GOYAL (guarantor)

Edition

CLINICAL NEURORADIOLOGY, HEIDELBERG, SPRINGER HEIDELBERG, 2021, 1869-1439

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.156

RIV identification code

RIV/00216224:14110/21:00120749

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s00062-020-00958-3

UT WoS

000572716700001

Keywords in English

Ischemic stroke; Collaterals; Large vessel occlusion

Abstract

V originále

Background Multiphase CTA (mCTA) is an established tool for endovascular treatment decision-making and outcome prediction in acute ischemic stroke, but its interpretation requires some degree of experience. We aimed to determine whether mCTA-based prediction of clinical outcome and final infarct volume can be improved by assessing collateral status on time-variant mCTA color maps rather than using a conventional mCTA display format. Methods Patients from the PRove-IT cohort study with anterior circulation large vessel occlusion were included in this study. Collateral status was assessed with a three-point scale using the conventional display format. Collateral extent and filling dynamics were then graded on a three-point scale using time-variant mCTA color-maps (FastStroke, GE Healthcare, Milwaukee, WI, USA). Multivariable logistic regression was performed to determine the association of conventional collateral score, color-coded collateral extent and color-coded collateral filling dynamics with good clinical outcome and final infarct volume (volume below vs. above median infarct volume in the study sample). Results A total of 285 patients were included in the analysis and 53% (152/285) of the patients achieved a good outcome. Median infarct volume on follow-up was 12.6ml. Color-coded collateral extent was significantly associated with good outcome (adjusted odds ratio [adjOR] 0.53, 95% confidence interval [CI]:0.36-0.77) while color-coded collateral filling dynamics (adjOR 1.30 [95%CI:0.88-1.95]) and conventional collateral scoring (adjOR 0.72 [95%C:0.48-1.08]) were not. Both color-coded collateral extent (adjOR 2.67 [95%CI:1.80-4.00]) and conventional collateral scoring (adjOR 1.84 [95%CI:1.21-2.79]) were significantly associated with follow-up infarct volume, while color-coded collateral filling dynamics were not (adjOR 1.21 [95%CI:0.83-1.78]). Conclusion In this study, collateral extent assessment on time-variant mCTA maps improved prediction of good outcome and has similar value in predicting follow-up infarct volume compared to conventional mCTA collateral grading.

Citovat

OSPEL, Johanna M., Petra CIMFLOVÁ, Ondřej VOLNÝ, Wu QIU, Moiz HAFEEZ, Arnuv MAYANK, Mohamed NAJM, Kevin CHUNG, Nima KASHANI, Mohammed A. ALMEKHLAFI, Bijoy K. MENON and Mayank GOYAL. Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion. CLINICAL NEURORADIOLOGY. HEIDELBERG: SPRINGER HEIDELBERG, 2021, vol. 31, No 3, p. 783-790. ISSN 1869-1439. Available from: https://dx.doi.org/10.1007/s00062-020-00958-3.

@article{1684436,
   author = {Ospel, Johanna M. and Cimflová, Petra and Volný, Ondřej and Qiu, Wu and Hafeez, Moiz and Mayank, Arnuv and Najm, Mohamed and Chung, Kevin and Kashani, Nima and Almekhlafi, Mohammed A. and Menon, Bijoy K. and Goyal, Mayank},
   article_location = {HEIDELBERG},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s00062-020-00958-3},
   keywords = {Ischemic stroke; Collaterals; Large vessel occlusion},
   language = {eng},
   issn = {1869-1439},
   journal = {CLINICAL NEURORADIOLOGY},
   title = {Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion},
   url = {https://link.springer.com/article/10.1007/s00062-020-00958-3},
   volume = {31},
   year = {2021}
}

TY  - JOUR
ID  - 1684436
AU  - Ospel, Johanna M. - Cimflová, Petra - Volný, Ondřej - Qiu, Wu - Hafeez, Moiz - Mayank, Arnuv - Najm, Mohamed - Chung, Kevin - Kashani, Nima - Almekhlafi, Mohammed A. - Menon, Bijoy K. - Goyal, Mayank
PY  - 2021
TI  - Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion
JF  - CLINICAL NEURORADIOLOGY
VL  - 31
IS  - 3
SP  - 783-790
EP  - 783-790
PB  - SPRINGER HEIDELBERG
SN  - 18691439
KW  - Ischemic stroke
KW  - Collaterals
KW  - Large vessel occlusion
UR  - https://link.springer.com/article/10.1007/s00062-020-00958-3
L2  - https://link.springer.com/article/10.1007/s00062-020-00958-3
N2  - Background Multiphase CTA (mCTA) is an established tool for endovascular treatment decision-making and outcome prediction in acute ischemic stroke, but its interpretation requires some degree of experience. We aimed to determine whether mCTA-based prediction of clinical outcome and final infarct volume can be improved by assessing collateral status on time-variant mCTA color maps rather than using a conventional mCTA display format. Methods Patients from the PRove-IT cohort study with anterior circulation large vessel occlusion were included in this study. Collateral status was assessed with a three-point scale using the conventional display format. Collateral extent and filling dynamics were then graded on a three-point scale using time-variant mCTA color-maps (FastStroke, GE Healthcare, Milwaukee, WI, USA). Multivariable logistic regression was performed to determine the association of conventional collateral score, color-coded collateral extent and color-coded collateral filling dynamics with good clinical outcome and final infarct volume (volume below vs. above median infarct volume in the study sample). Results A total of 285 patients were included in the analysis and 53% (152/285) of the patients achieved a good outcome. Median infarct volume on follow-up was 12.6ml. Color-coded collateral extent was significantly associated with good outcome (adjusted odds ratio [adjOR] 0.53, 95% confidence interval [CI]:0.36-0.77) while color-coded collateral filling dynamics (adjOR 1.30 [95%CI:0.88-1.95]) and conventional collateral scoring (adjOR 0.72 [95%C:0.48-1.08]) were not. Both color-coded collateral extent (adjOR 2.67 [95%CI:1.80-4.00]) and conventional collateral scoring (adjOR 1.84 [95%CI:1.21-2.79]) were significantly associated with follow-up infarct volume, while color-coded collateral filling dynamics were not (adjOR 1.21 [95%CI:0.83-1.78]). Conclusion In this study, collateral extent assessment on time-variant mCTA maps improved prediction of good outcome and has similar value in predicting follow-up infarct volume compared to conventional mCTA collateral grading.
ER  -

OSPEL, Johanna M., Petra CIMFLOVÁ, Ondřej VOLNÝ, Wu QIU, Moiz HAFEEZ, Arnuv MAYANK, Mohamed NAJM, Kevin CHUNG, Nima KASHANI, Mohammed A. ALMEKHLAFI, Bijoy K. MENON and Mayank GOYAL. Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion. \textit{CLINICAL NEURORADIOLOGY}. HEIDELBERG: SPRINGER HEIDELBERG, 2021, vol.~31, No~3, p.~783-790. ISSN~1869-1439. Available from: https://dx.doi.org/10.1007/s00062-020-00958-3.

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