Well-Blended PCL/PEO Electrospun Nanofibers with Functional
Properties Enhanced by Plasma Processing

J 2020

Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing

KUPKA, Vojtěch, Eva DVOŘÁKOVÁ, Anton MANAKHOV, Miroslav MICHLÍČEK, Josef PETRUŠ et. al.

Základní údaje

Originální název

Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing

Autoři

KUPKA, Vojtěch (203 Česká republika), Eva DVOŘÁKOVÁ (203 Česká republika, domácí), Anton MANAKHOV (643 Rusko, domácí), Miroslav MICHLÍČEK (203 Česká republika, domácí), Josef PETRUŠ, Lucy VOJTOVÁ a Lenka ZAJÍČKOVÁ (203 Česká republika, garant, domácí)

Vydání

Polymers, Basel, MDPI, 2020, 2073-4360

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10305 Fluids and plasma physics

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.329

Kód RIV

RIV/00216224:14310/20:00114428

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.3390/polym12061403

UT WoS

000553918200001

Klíčová slova anglicky

polymer fibers; thin films; plasma enhanced CVD; mechanical properties; SEM

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 3. 2024 14:48, Mgr. Marie Šípková, DiS.

Anotace

V originále

Biodegradable composite nanofibers were electrospun from poly(epsilon-caprolactone) (PCL) and poly(ethylene oxide) (PEO) mixtures dissolved in acetic and formic acids. The variation of PCL:PEO concentration in the polymer blend, from 5:95 to 75:25, revealed the tunability of the hydrolytic stability and mechanical properties of the nanofibrous mats. The degradation rate of PCL/PEO nanofibers can be increased compared to pure PCL, and the mechanical properties can be improved compared to pure PEO. Although PCL and PEO have been previously reported as immiscible, the electrospinning into nanofibers having restricted dimensions (250-450 nm) led to a microscopically mixed PCL/PEO blend. However, the hydrolytic stability and tensile tests revealed the segregation of PCL into few-nanometers-thin fibrils in the PEO matrix of each nanofiber. A synergy phenomenon of increased stiffness appeared for the high concentration of PCL in PCL/PEO nanofibrous mats. The pure PCL and PEO mats had a Young's modulus of about 12 MPa, but the mats made of high concentration PCL in PCL/PEO solution exhibited 2.5-fold higher values. The increase in the PEO content led to faster degradation of mats in water and up to a 20-fold decrease in the nanofibers' ductility. The surface of the PCL/PEO nanofibers was functionalized by an amine plasma polymer thin film that is known to increase the hydrophilicity and attach proteins efficiently to the surface. The combination of different PCL/PEO blends and amine plasma polymer coating enabled us to tune the surface functionality, the hydrolytic stability, and the mechanical properties of biodegradable nanofibrous mats.

Návaznosti

GA18-12774S, projekt VaV

Název: Plazmové polymery připravené na nanovlákenných membránách pro inženýrství cévní tkáně

Investor: Grantová agentura ČR, Plazmové polymery připravené na nanovlákenných membránách pro inženýrství cévní tkáně

LQ1601, projekt VaV

Název: CEITEC 2020 (Akronym: CEITEC2020)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC 2020

Citovat

KUPKA, Vojtěch, Eva DVOŘÁKOVÁ, Anton MANAKHOV, Miroslav MICHLÍČEK, Josef PETRUŠ, Lucy VOJTOVÁ a Lenka ZAJÍČKOVÁ. Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing. Polymers. Basel: MDPI, 2020, roč. 12, č. 6, s. 1-16. ISSN 2073-4360. Dostupné z: https://dx.doi.org/10.3390/polym12061403.

@article{1689018,
   author = {Kupka, Vojtěch and Dvořáková, Eva and Manakhov, Anton and Michlíček, Miroslav and Petruš, Josef and Vojtová, Lucy and Zajíčková, Lenka},
   article_location = {Basel},
   article_number = {6},
   doi = {http://dx.doi.org/10.3390/polym12061403},
   keywords = {polymer fibers; thin films; plasma enhanced CVD; mechanical properties; SEM},
   language = {eng},
   issn = {2073-4360},
   journal = {Polymers},
   note = {doc. Zajíčková - dle rozhodnutí ředitelů 5.3.2024},
   title = {Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing},
   url = {https://www.mdpi.com/2073-4360/12/6/1403},
   volume = {12},
   year = {2020}
}

TY  - JOUR
ID  - 1689018
AU  - Kupka, Vojtěch - Dvořáková, Eva - Manakhov, Anton - Michlíček, Miroslav - Petruš, Josef - Vojtová, Lucy - Zajíčková, Lenka
PY  - 2020
TI  - Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing
JF  - Polymers
VL  - 12
IS  - 6
SP  - 1-16
EP  - 1-16
PB  - MDPI
SN  - 20734360
N1  - doc. Zajíčková - dle rozhodnutí ředitelů 5.3.2024
KW  - polymer fibers
KW  - thin films
KW  - plasma enhanced CVD
KW  - mechanical properties
KW  - SEM
UR  - https://www.mdpi.com/2073-4360/12/6/1403
L2  - https://www.mdpi.com/2073-4360/12/6/1403
N2  - Biodegradable composite nanofibers were electrospun from poly(epsilon-caprolactone) (PCL) and poly(ethylene oxide) (PEO) mixtures dissolved in acetic and formic acids. The variation of PCL:PEO concentration in the polymer blend, from 5:95 to 75:25, revealed the tunability of the hydrolytic stability and mechanical properties of the nanofibrous mats. The degradation rate of PCL/PEO nanofibers can be increased compared to pure PCL, and the mechanical properties can be improved compared to pure PEO. Although PCL and PEO have been previously reported as immiscible, the electrospinning into nanofibers having restricted dimensions (250-450 nm) led to a microscopically mixed PCL/PEO blend. However, the hydrolytic stability and tensile tests revealed the segregation of PCL into few-nanometers-thin fibrils in the PEO matrix of each nanofiber. A synergy phenomenon of increased stiffness appeared for the high concentration of PCL in PCL/PEO nanofibrous mats. The pure PCL and PEO mats had a Young's modulus of about 12 MPa, but the mats made of high concentration PCL in PCL/PEO solution exhibited 2.5-fold higher values. The increase in the PEO content led to faster degradation of mats in water and up to a 20-fold decrease in the nanofibers' ductility. The surface of the PCL/PEO nanofibers was functionalized by an amine plasma polymer thin film that is known to increase the hydrophilicity and attach proteins efficiently to the surface. The combination of different PCL/PEO blends and amine plasma polymer coating enabled us to tune the surface functionality, the hydrolytic stability, and the mechanical properties of biodegradable nanofibrous mats.
ER  -

KUPKA, Vojtěch, Eva DVOŘÁKOVÁ, Anton MANAKHOV, Miroslav MICHLÍČEK, Josef PETRUŠ, Lucy VOJTOVÁ a Lenka ZAJÍČKOVÁ. Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing. \textit{Polymers}. Basel: MDPI, 2020, roč.~12, č.~6, s.~1-16. ISSN~2073-4360. Dostupné z: https://dx.doi.org/10.3390/polym12061403.

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